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Antibody responses to keyhole limpet hemocyanin, lipopolysaccharide and Newcastle disease virus vaccine in F2 and backcrosses of White Leghorn lines selected for two different immune response traits Inra
Minozzi, G.; PARMENTIER, H.K.; NIEUWLAND, M.G.B.; Bed'Hom, B.; Minvielle, F.; Gourichon, D.; PINARD-VAN DER LAAN, M.H..
Planned crosses were designed to producean F2 and 2 backcross populations from 2 lines of WhiteLeghorn chickens previously selected over 10 generationsfor 2 different in vivo immune responses. The selectioncriteria applied on the 2 grandparental lines were as follows:high antibody response to Newcastle disease virusvaccine 3 wk after vaccination (ND3) and high cell-mediatedimmune response [response to phytohemagglutinin].Furthermore a control line was kept by randombreeding. The objective of the study was to estimate ifthe 2 selection criteria applied on the pure lines hadchanged the level of and type of immune (humoral) responseto a new antigen, keyhole limpet hemocyanin(KLH), in the various second-generation progeny groups.In addition, correlations...
Tipo: Journal Article Palavras-chave: PRIMARY ANTIBODY RESPONSE; CHICKEN; KEYHOLE LIMPET HMOCYANIN; SALMONELLA ENTERIDITIS-DERIVED LIPOPOLYSACCHARIDE; SELECTION.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2008781c73d2&uri=/notices/prodinra1/2008/08/
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