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Registros recuperados: 25
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A Mechanism of Excessive Accumulation of Abomasal Gas in Vagotomized Cattle Determined using Fluoroscopy OAK
ITOH, Megumi; SASAKI, Naoki; KAWAMOTO, Satoshi; YAMADA, Haruo; INOKUMA, Hisashi; 佐々木, 直樹; 猪熊, 壽.
To better understand the mechanism of excessive gas accumulation in the abomasum in bovine abomasal displacement, we performed gastric fluoroscopy in vagotomized cattle. Fifteen 6-month-old Holstein steers were divided into three groups: a non-vagotomized control group (Group C; n=5), a ventral thoraco-vagotomized group (Group V; n=5), and a dorsal and ventral thoraco-vagotomized group (Group DV; n=5). These groups were examined by fluoroscopy before and during a 5-week observation period after surgery. In Group C, no change was observed throughout the observation period. In Group DV, immediately after surgery, reticuloruminal motility was completely absent and ruminal distention was seen. Two weeks after surgery, abnormal reticulum motility and increased...
Palavras-chave: Abomasum gas; Cattle; Displaced abomasum; Vagotomy.
Ano: 2011 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3888
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A Preliminary Study of 13C-Phenylalanine and 13C-Dipeptide Breath Tests in Horses OAK
SASAKI, Naoki; TSUZUKI, Nao; YAMADA, Michiaki; MINAMI, Takuto; YAMADA, Haruo; 佐々木, 直樹.
This study aimed to establish a standard dose and sample collection time for 13C phenylalanine and 13C-Dipeptide breath test in horses. To evaluate dose-dependent effects, healthy horses received 2.5 mg/kg, 5 mg/kg, and 10 mg/kg 13C phenylalanine dissolved in 1 ml/kg distilled water and 1.25 mg/kg, 2.5 mg/kg, and 5 mg/kg 13C dipeptide dissolved in 2 ml/kg distilled water. Tmax was observed during the sample collection time. For 13C phenylalanine, the standard deviation of Cmax at 5 mg/kg was lower than that of 10 mg/kg. For 13C dipeptide, the standard deviation of Tmax was the lowest at 5 mg/kg. This study revealed that an optimal dose for breath tests with 13C phenylalanine and 13C dipeptide may be 5 mg/kg in horses.
Palavras-chave: 13C-breath test; Dipeptide; Horses; Phenylalanine.
Ano: 2009 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3105
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Basic Assessment of Diagnosis by MDCT in Horses OAK
SASAKI, Naoki; KIKUCHI, Takuya; YAMADA, Kazutaka; HIGUCHI, Tohru; SATO, Motoyoshi; YAMADA, Haruo; 佐々木, 直樹; 山田, 一孝.
In this equine study, we used an MDCT unit and a trestle for large animals to assess the utility of MDCT in the diagnosis locomotor system disorders and problems in the head and spine. We used a mature thoroughbred horse under general anesthesia and 5 specimens. For specimens, MDCT images were compared with other images taken by a computed radiography X-ray unit. In the live horse, use of the trestle for large animals enabled scanning under general anesthesia. In specimens, MDCT created 3D images of the fractured lesions and evaluation of multiple cross-sectional and sagittal images was possible. Further, multiple sagittal images and virtual endoscopic images revealed details of a spinal canal stenosis in the swayback case. These results indicate that MDCT...
Palavras-chave: Equine; Locomotor system disorders; MDCT; 3D image analysis.
Ano: 2007 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3103
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Clinical Applications of Electrointestinography in the Horse OAK
SASAKI, Naoki; LEE, Inhyung; AYUKAWA, Yu; YAMADA, Haruo; 佐々木, 直樹.
It is thought that in order to effectively treat gastrointestinal dysfunction, it should be detected at an early stage. The present study aimed to observe the movement via Electrointestinography (EIG) in the small intestine, cecum, right ventral colon and right dorsal colon, and to examine the procedure for assessing gastrointestinal function. Seven healthy thoroughbred horses were used. They were allowed food twice a day. EIG was measured at ten-minute intervals over a 24 hr period, and running spectral analysis was used. As a result, it was clear that EIG could non-invasively assess gastrointestinal function by setting the cut-off value of the frequency band to 1.8-12.0 cpm for a part of the digestive tract which is in a comparatively fixed position. The...
Palavras-chave: Electrointestinography; Equine; Intestine; Power spectral analysis; Running spectral analysis.
Ano: 2004 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3101
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Effect of Compound of Gelatin Hydrogel Microsphere Incorporated with Platelet-Rich-Plasma and Alginate on Sole Defect in Cattle OAK
TSUZUKI, Nao; SEO, Jong-Pil; YAMADA, Kazutaka; HANEDA, Shingo; TABATA, Yasuhiko; SASAKI, Naoki; 羽田, 真悟; 佐々木, 直樹.
Platelet-rich plasma (PRP) was administered to cattle with hoof defects (10-mm drill hole) to promote sole defect healing. Two types of gels were prepared. One was a mixed gel [compound of gelatin microspheres (GM) incorporated with PRP and alginate] and was used for the test group, while the other was an alginate gel used for the control group. Each hole was filled with one of these gels. The drill hole depth, pressure pain, and hardness of the regenerated tissue were measured for 3 weeks after treatment. These measurements improved significantly in the test group than in the control group. The results suggest that a compound of GM incorporated with PRP and alginate had a hoof-regenerating effect in cattle.
Ano: 2012 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3889
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Effects of Orally Administrated Mosapride, a 5-HT4 Receptor Agonist on the Digestive Tract of Horses OAK
SASAKI, Naoki; LEE, Inhyung; AYUKAWA, Yu; YAMADA, Haruo; 佐々木, 直樹.
The effects of mosapride, a 5-hydroxytryptamine 4 (5-HT4) receptor agonist, on the motility of horse small intestine were examined by means of electrointestinography (EIG). Six adult healthy thoroughbreds were used, in which EIG signals from the small intestine were measured by a Degetorappar EGG system. Mosapride, dissolved in 200 ml water, was orally administered at a dose of 2 mg/kg. The total power of EIG signals at a frequency band of 3 cpm was 419.1 ± 122.0 (μV) 2 × cpm (n=6) before, and 2,093.6 ± 850.0 (μV)2 × cpm (n=6) after the drug administration, the latter mean value being significantly greater than the former. This result suggests that mosapride has a prokinetic action on the motility of horse small intestine.
Palavras-chave: Equine; Gastrokinetic agent; Mosapride; Oral administration; 5-HT4 receptor agonist.
Ano: 2004 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3100
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Evaluation of Motion Correction Processing in Equine Bone Scintigraphy by Scheffé’s Method of Paired Comparisons OAK
YAMAGUCHI, Toshiro; ENDO, Yoshiro; NAMBO, Yasuo; SATO, Fumio; SASAKI, Naoki; YAMADA, Kazutaka; 南保, 泰雄; 佐々木, 直樹; 山田, 一孝.
Equine bone scintigraphy is usually performed with horses in standing position under sedation. However, swaying motion often leads to poor-quality images. To examine the usefulness of motion correction (MC) processing, equine bone scintigrams were evaluated using Scheffé’s method of paired comparisons. A significant difference in evaluation scores was detected by analysis of variance (F test, P<0.01). According to all observers, Yardstick analysis scores were higher for images use of MC processing than for those no use of MC processing, for all parts. Overall scores of 5 observers were as follows: without MC 100% acquisition time (AT, lowest), use of MC with 25% AT, MC 50% AT, MC 75% AT and MC 100% AT (highest). Thus, MC processing shortens AT in equine...
Palavras-chave: Bone scintigraphy; Equine; Motion correction; Scheffé’s method of paired comparisons.
Ano: 2013 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3894
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Evaluation of Techniques That Measure Hydrogen and Methane Levels in Breaths of Horses with Gastrointestinal Diseases OAK
SASAKI, Naoki; FUKUNAKA, Morito; YAMADA, Haruo; SENBA, Hiroyuki; HIGUCHI, Tohru; 佐々木, 直樹.
Techniques for measuring hydrogen (H2) and methane (CH4) levels in breaths were assessed in horses with gastrointestinal (GI) diseases. A total of 31 horses were studied: 11 healthy horses (Group A), 10 horses with GI diseases (Group B), and 10 horses with diseases without GI involvement (Group C). Expired gases were measured using gas chromatography. CH4 levels in Group A were significantly lower than those in Group B. In Group B, CH4 levels were significantly higher after treatment. Fluctuations in H2 and CH4 levels in breath were associated with changes in GI function.
Palavras-chave: Equine; Hydrogen; Methane.
Ano: 2006 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3102
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Evaluation of the Cranial Cruciate Ligament Repair System® in Surgery for Laryngeal Hemiplegia in Heavy Draft Horses OAK
SASAKI, Naoki; MORITA, Yoshinori; MORIYAMA, Tomoe; YAMADA, Haruo; 佐々木, 直樹.
The purpose of this study was to evaluate the effect of the canine cranial cruciate ligament repair system on laryngeal hemiplegia in heavy draft horses. Twenty-four heavy draft horses diagnosed with grade 4 laryngeal hemiplegia were allocated to either the prosthetic laryngoplasty (PL) group (n=14) or a canine cranial cruciate ligament repair system (CCCLRS) group (n=10). Right to left angle quotients (RLQs) of abductions of the arytenoid cartilages were endoscopically evaluated before and after surgery. Post-operative RLQs in the CCCLRS group were significantly lower than those of the PL group (P<0.01). The canine cranial cruciate ligament repair system was revealed to be a good surgical procedure for laryngeal hemiplegia in heavy draft horses.
Palavras-chave: Canine cranial cruciate ligament repair system; Equine; Laryngoplasty.
Ano: 2009 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3106
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Experimental investigation of bone mineral density in Thoroughbreds using quantitative computed tomography OAK
YAMADA, Kazutaka; SATO, Fumio; HIGUCHI, Tohru; NISHIHARA, Kaori; KAYANO, Mitsunori; SASAKI, Naoki; NAMBO, Yasuo.
Bone mineral density (BMD) is one of the indications of the strength and health. BMD measured by quantitative computed tomography (QCT) was compared with that measured by dual energy X-ray absorptiometry (DXA) and radiographic bone aluminum equivalence (RBAE). Limbs were removed from horses that had been euthanized for reasons not associated with this study. Sixteen limbs (left and right metacarpals and metatarsals) from 4 horses were used to compare BMD as measured by QCT with those measured by DXA and RBAE. There was a strong correlation between BMD values measured by QCT and those measured by DXA (R2=0.85); correlation was also observed between values obtained by QCT and those obtained by RBAE (R2=0.61). To investigate changes in BMD with age, 37 right...
Palavras-chave: Bone mineral density; Dual energy X-ray absorptiometry; Quantitative computed tomography; Radiographic bone aluminum equivalence; Thoroughbred.
Ano: 2015 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4182
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Four cases of equine motor neuron disease in Japan OAK
SASAKI, Naoki; IMAMURA, Yui; SEKIYA, Akio; ITOH, Megumi; FURUOKA, Hidefumi.
In this study, fasciculation of the limbs and tongue was observed in four horses kept by a riding club. Neurogenic muscle atrophy was also observed in biopsy of pathological tissues. In addition, in two cases that subjected to autopsy, Bunina-like bodies of inclusion in the cell bodies of neurons in the spinal cord ventral horn were confirmed, leading to a diagnosis of equine motor neuron disease (EMND). Serum vitamin E concentrations varied between 0.3 and 0.4µg/ml, which is significantly lower than the levels in normal horses. Although lack of vitamin E is speculated to be a contributory factor for development of EMND, no significant improvement was observed following administration of vitamin E.
Ano: 2016 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4376
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MDCT Images of the Head of a Horse with Malignant Melanoma OAK
SASAKI, Naoki; MINAMI, Takuto; YAMADA, Kazutaka; SATOH, Motoyoshi; INOKUMA, Hisashi; KOBAYASHI, Yoshiyasu; FURUOKA, Hidefumi; YAMADA, Haruo; 佐々木, 直樹; 山田, 一孝; 猪熊, 壽; 古林, 与志安; 古岡, 秀文.
A 17-year-old, gray Thoroughbred gelding was presented with recurrent epistaxis following exercise for over one year. Multidetector-row computed tomographic (MDCT) examination of the head performed under general anesthesia indicated the presence of malignant melanoma. MDCT examination revealed the exact location and size of masses in the right guttural pouch first identified by endoscopy and in the left guttural pouch unidentified by endoscopy. MDCT examination revealed the presence of a blood clot that filled the right maxillary sinus. The horse was euthanized due to poor prognosis as a riding horse and the owner's decision, and MDCT findings were confirmed by postmortem examination. MDCT is suggested as a useful technique for diagnosis of head problems...
Palavras-chave: Equine; Malignant melanoma; MDCT.
Ano: 2007 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3104
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Medicinal Treatment to Equine Gastrointestinal Dysfunctions OAK
SASAKI, Naoki; YAMADA, Haruo; HARA, Shigeo; 佐々木, 直樹.
This study was designed to investigate gastrointestinal dysfunctions, especially the effects of gastrointestinal prokinetic agents on digestive disorders involving lowered motility. The effects of α2-adrenergic agonists for treating acute abdominal disorders involving intestinal torsion in horses were also investigated. The results are as follows: (1) It appeared that the functions of migrating contractions (MC) in horses were to transfer the contents of the digestive tract as soon as possible to the cecum and colon, in addition to maintaining homeostatis in the digestive tract. (2) Motilin was seen to be involved in the regulation mechanism of intestinal motility in the horse as well as in humans and dogs, and brought about MC. (3) The intravenous...
Palavras-chave: Α2-adrenergic agonist; Equine; Gastrointestinal dysfunction; Motility; Serotonin receptor agonist.
Ano: 2003 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3099
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Preliminary Experiment on the Suppression of Cesium Uptake into the Organs by Bentonite Using a Stable Isotope of Cesium in Calves OAK
山田, 一孝; 山口, 敏朗; 陳, 忠正; 稲沢, 直生実; 石井, 三都夫; 佐々木, 基樹; 木田, 克弥; 岸本, 海織; 古濱, 和久; YAMADA, Kazutaka; ISHII, Mitsuo; SASAKI, Naoki; KIDA, Katsuya.
ベントナイトのセシウム体内移行抑制効果について調べた。実験には,ホルスタイン種子牛6頭を使用し,28日の実験期間中,全頭に安定同位体の塩化セシウム(3.0mg/kg/day)を人工乳に溶解し,投与した。塩化セシウムに加えベントナイト0.5w/v%を人工乳に懸濁した投与群(n=3)と塩化セシウムのみの対照群(n=3)の2群を設定した。実験開始0,1,2,3,7,14,21および28日目に採血,28日目に骨格筋,心臓,肝臓,腎臓および糞便を採材し,ICP-MS (inductively coupled plasma mass spectrometry) によるセシウム濃度を測定した。臓器中のセシウム濃度からベントナイトの効果は明らかではなかったが,血球中セシウム濃度平均値は投与後14日まで投与群が対照群よりも低値を示した。このことから,ベントナイトによるセシウム体内移行抑制効果の可能性が示唆された。
Palavras-chave: ベントナイト; 子牛; 塩化セシウム.
Ano: 2013 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3898
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Use of Contrast-Enhanced CT in the Diagnosis of Abscesses in Cattle OAK
LEE, Ki-Ja; KISHIMOTO, Miori; SHIMIZU, Junichiro; KOBAYASHI, Yoshiyasu; MATSUMOTO, Kotaro; SASAKI, Naoki; ISHII, Mitsuo; INOKUMA, Hisashi; IWASAKI, Toshiroh; MIYAKE, Yoh-Ichi; YAMADA, Kazutaka; 古林, 与志安; 松本, 高太郎; 佐々木, 直樹; 石井, 三都夫; 猪熊, 壽; 山田, 一孝.
We report here the non-contrast and contrast-enhanced computed tomography performed in two calves with brain abscess and multiple pulmonary abscesses with pharyngeal abscess, respectively. Contrast-enhanced computed tomography was useful in the diagnosis of these diseases in both calves. The diseases were confirmed by histopathological examination.
Palavras-chave: Abscess; Cattle; Contrast-enhanced CT; Diagnosis.
Ano: 2011 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3891
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ウマの胃排出能に対するクエン酸モサプリドの促進効果(内科学) OAK
OKAMURA, Koichi; SASAKI, Naoki; FUKUNAKA, Morito; YAMADA, Haruo; INOKUMA, Hisashi; 佐々木, 直樹; 猪熊, 壽.
The prokinetic effect of the 5-HT4 receptor agonist mosapride was evaluated in seven healthy thoroughbreds. Mosapride was orally administerd at doses of 0.5, 1.0 or 1.5 mg/kg. The breath 13CO2/12CO2 rate (Δ13CO2), an indirect indicator for the rate of gastric empting, was measured at appropriate points for 4 hr after drug administration. There was a significant increase compared with the control value at 15, 20 and 165 min for 0.5 mg/kg, 30 min at 1.0 mg/kg and 165 min for 1.5 mg/kg. The results suggest that mosapride may facilitate the gastric emptying in horses.
Palavras-chave: Equine; Gastric emptying rate; Mosapride citrate.
Ano: 2008 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4019
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ホルスタイン種育成雄牛の中手骨粉骨折に対してダブル・ロッキング・コンプレッション・プレートを用いた一症例 OAK
今村, 唯; 長島, 剛史; 奥原, 秋津; 柳川, 将志; 伊藤, めぐみ; 佐々木, 直樹; YANAGAWA, Masashi; ITO, Megumi; SASAKI, Naoki.
Ano: 2016 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4379
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ポータブルX線撮影装置を用いた牛の Computed Radiography 画像化因子が画質に与える影響 OAK
岸本, 海織; 住谷, 峻; 李, 奇子; 清水, 純一郎; 山川, 和宏; 滄木, 孝弘; 羽田, 真悟; 松本, 高太郎; 石井, 三都夫; 佐々木, 直樹; 猪熊, 壽; 山田, 一孝; KISHIMOTO, Miori; SUMIYA, Takashi; LEE, Ki-Ja; SHIMIZU, Junichiro; YAMAKAWA, Kazuhiro; AOKI, Takahiro; HANEDA, Shingo; MATSUMOTO, Kotaro; ISHII, Mitsuo; SASAKI, Naoki; INOKUMA, Hisashi; YAMADA, Kazutaka.
牛臨床におけるComputed Radiography (CR) の有用性を確立するため,管球-カセッテ間距離およびImaging Plate (IP) の読み取り時間が画質に与える影響について検討した.管球-カセッテ間距離は画質の視覚的スコア(粒状性,鮮鋭性)に影響しなかった. IPの読み取り時間は画質の鮮鋭性と相関しなかったが,粒状性と相関が認められた.しかし読み取り時聞が12時間以内の場合には問題にならない程度であると考えられた.管球-力セッテ間距離を再現よく保つことが難しく, IP読み取り時間のばらつきが想定される牛の臨床画像診断においてCRは有用なX線撮影システムであると考えられた. The purpose of this study was to investigate the effect of X-ray tube-cassette distance and image scanning time on image quality to establish the benefit of Computed Radiography (CR) in bovine clinical practice. The tube-cassette distance had no effect on the visual evaluation score (graininess and sharpness). The image scanning time correlated with graininess but not sharpness. From these results,it was concluded that accidental variations in the tube-cassette...
Palavras-chave: ; Computed Radiography (CR); フェーデイング; Imaging Plate (IP); ポータブルX線発生装置; Bovine; Computed Radiography (CR); Fading; Imaging Plate (lP); Portable x-ray generator.
Ano: 2010 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2939
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乳牛の蹄底潰瘍に対する多血小板血漿含浸ゼラチンマイクロスフィアの効果 OAK
内山, 裕貴; 都築, 直; 徐, 鍾筆; 山田, 一孝; 羽田, 真悟; 眞鍋, 弘行; 田畑, 泰彦; 佐々木, 直樹; HANEDA, Shingo; SASAKI, Naoki.
自家血液から作製された多血小板血漿(Platelet rich plasma,以下PRP)は,アルギン酸ゲル剤として患部に塗布することで蹄底潰瘍への良好な治癒効果が認められた.しかし,効果を持続させるという点で不十分な方法であった.そこで本研究では,徐放剤としてゼラチンマイクロスフィア(以下 GM)を用いた新しい塗布剤を作製し,治療効果を検討した.PRP含浸GM混合アルギン酸ゲル処置群(PRP群,n=10)とアルギン酸ゲルのみ処置群 (対照群,n=9)を比較した.蹄底潰瘍面積の欠損割合は,PRP群で処置後1,2及び3週目で約45%,17%及び5%と推移し,対照群と比較して有意な角質再生効果がみられた.また,PRP群では処置後2週目に圧痛が消失したが,対照群では痛みは継続していた.以上のことから,PRP含浸GM混合アルギン酸ゲルは乳牛の蹄底潰瘍に有効であることが明らかとなった.
Palavras-chave: ゼラチンマイクロスフィア; 多血小板血漿 蹄底潰瘍.
Ano: 2013 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3886
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十勝地区における馬の疝痛発症状況 OAK
上林, 義範; 都築, 直; 徐, 鍾筆; 大下, のえ; 中尾, 奨吾; 田邊, 貴史; 山家, 崇史; 内山, 裕貴; 佐々木, 直樹; SASAKI, Naoki.
十勝地区において疝痛を発症した馬36頭を対象として、疝痛発症の危険因子および疝痛を発症した馬の予後 に関する疫学調査を実施した。調査の結果から、十勝地区における馬の疝痛発症には、過去の疝痛既往歴、駆 虫剤投与歴、飼養管理の急変などが関連していることが推測された。疝痛の種類別に来院時のヘマトクリット 値を比較すると、便秘疝の馬では変位疝や風気疝の馬と比較して有意に高値を示した。手術実施馬において、 疝痛発症から来院までの時間が長いほど予後が悪化する傾向がみられた。また、予後不良となった馬では術後 経過が良好で退院した馬と比較して、心拍数が有意に高値を示すということが判明した。
Palavras-chave: ; 疝痛; 調査.
Ano: 2012 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4023
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