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Assessing signatures of selection through variation in linkage disequilibrium between taurine and indicine cattle. Repositório Alice
O'BRIEN, A. M. P.; UTSUNOMIYA, Y. T.; MÉSZÁROS, G.; BICKHART, D. M.; LIU, G. E.; TASSEL, C. P. V.; SONSTEGARD, T. S.; SILVA, M. V. G. B.; GARCIA, J. F.; SÖLKNER, J..
Signatures of selection are regions in the genome that have been preferentially increased in frequency and fixed in a population because of their functional importance in specific processes. These regions can be detected because of their lower genetic variability and specific regional linkage disequilibrium (LD) patterns. By comparing the differences in regional LD variation between dairy and beef cattle types, and between indicine and taurine subspecies, we aim at finding signatures of selection for production and adaptation in cattle breeds. The VarLD method was applied to compare the LD variation in the autosomal genome between breeds, including Angus and Brown Swiss, representing taurine breeds, and Nelore and Gir, representing indicine breeds. The...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Cattle - genetic improvement; Indicine; Linkage disequilibrium; Minor allele frequency; Taurine.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1006605
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Genome-wide scan of gastrointestinal nematode resistance in closed Angus population selected for minimized influence of MHC. Repositório Alice
KIM, E. S.; SONSTEGARD, T. S.; SILVA, M. V. G. B.; GASBARRE, L. C.; TASSEL, C. P. V..
Genetic markers associated with parasite indicator traits are ideal targets for study of marker assisted selection aimed at controlling infections that reduce herd use of anthelminthics. For this study, we collected gastrointestinal (GI) nematode fecal egg count (FEC) data from post-weaning animals of an Angus resource population challenged to a 26 week natural exposure on pasture. In all, data from 487 animals was collected over a 16 year period between 1992 and 2007, most of which were selected for a specific DRB1 allele to reduce the influence of potential allelic variant effects of the MHC locus. A genome-wide association study (GWAS) based on BovineSNP50 genotypes revealed six genomic regions located on bovine Chromosomes 3, 5, 8, 15 and 27; which...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Heritability; Cattle; Genetic markers.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1037193
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Validation of genomic regions influencing nematode resistance in a Bos taurus x Bos indicus cross population. Repositório Alice
BENAVIDES, M. V.; ECHEVARRIA, F. A. M.; SONSTEGARD, T. S.; TASSEL, C. P. V.; GASBARRE, L. C..
bitstream/item/180982/1/digitalizar0067.pdf
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bovino; Nematóide.
Ano: 2005 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1093939
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