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Registros recuperados: 12
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A comprehensive manually-curated compendium of bovine transcription factors. Repositório Alice
SOUZA, M. M. de; ZERLOTINI NETO, A.; GEISTLINGER, L.; TIZIOTO, P. C.; TAYLOR, J. F.; ROCHA, M. I. P.; DINIZ, W. J. S.; COUTINHO, L. L.; REGITANO, L. C. de A..
Transcription factors (TFs) are pivotal regulatory proteins that control gene expression in a contextdependent and tissue-specific manner. In contrast to human, where comprehensive curated TF collections exist, bovine TFs are only rudimentary recorded and characterized. In this article, we present a manually-curated compendium of 865 sequence-specific DNA-binding bovines TFs, which we analyzed for domain family distribution, evolutionary conservation, and tissue-specific expression. In addition, we provide a list of putative transcription cofactors derived from known interactions with the identified TFs. Since there is a general lack of knowledge concerning the regulation of gene expression in cattle, the curated list of TF should provide a basis for an...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: DNA bovino; Expressão gênica; Gene expression in cattle; Gene expression regulation.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1102174
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A comprehensive manually-curated compendium of bovine transcription factors. Repositório Alice
SOUZA, M. M. de; ZERLOTINI NETO, A.; GEISTLINGER, L.; TIZIOTO, P. C.; TAYLOR, J. F.; ROCHA, M. I. P.; DINIZ, W. J. S.; COUTINHO, L. L.; REGITANO, L. C. de A..
Transcription factors (TFs) are pivotal regulatory proteins that control gene expression in a contextdependent and tissue-specific manner. In contrast to human, where comprehensive curated TF collections exist, bovine TFs are only rudimentary recorded and characterized. In this article, we present a manually-curated compendium of 865 sequence-specific DNA-binding bovines TFs, which we analyzed for domain family distribution, evolutionary conservation, and tissue-specific expression. In addition, we provide a list of putative transcription cofactors derived from known interactions with the identified TFs. Since there is a general lack of knowledge concerning the regulation of gene expression in cattle, the curated list of TF should provide a basis for an...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: DNA bovine; Gene expression in cattle; Gene expression regulation.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1101203
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CRUMBLER: A tool for the prediction of ancestry in cattle. Repositório Alice
CRUM, T. E.; SCHNABEL, R. D.; DECKER, J. E.; REGITANO, L. C. de A.; TAYLOR, J. F..
In many beef and some dairy production systems, cross breedingis used to take advan-tage of breed complementarity and heterosis. Admixed animals are frequently identified by their coat color and body conformation phenotypes, however, without pedigree informa-tionit is not possible to identify the expected breed composition of an admixed animal and in the presence of selection, the actual composition may differ from expectation.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Dairy production systems; Pedigree information; Beef animals; Beef quality; Beef cattle.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1115504
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Effects of quantitative trait loci on iron content of bovine longissimus dorsi muscle. Repositório Alice
TIZIOTO, P. C.; TAYLOR, J. F.; DECKER, J. E.; GROMBONI, C. F.; MUDADU, M. de A.; SCHNABEL, R. D.; COUTINHO, L. L.; MOURÃO, G. B.; NASSU, R. T.; DONATONI, F. A. B.; THOLON, P.; SONSTEGARD, T. S.; ALENCAR, M. M. de; TULLIO, R. R.; REECY, J. M.; NOGUEIRA, A. R. de A.; REGITANO, L. C. de A..
2014
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Bos indicus; Fe; GWAS.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/997999
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Gene expression differences in Longissimus muscle of Nelore steers genetically divergent for residual feed intake. Repositório Alice
TIZIOTO, P. L.; COUTINHO, L. L.; OLIVEIRA, P. S. N.; CESAR, A. S. M.; DINIZ, W. J. S.; LIMA, A. O.; ROCHA, M. I.; DECKER, J. E.; SCHNABEL, R. D.; MOURÃO, G. B.; TULLIO, R. R.; ZERLOTINI NETO, A.; TAYLOR, J. F.; REGITANO, L. C. de A..
Residual feed intake (RFI), a measure of feed efficiency (FE), is defined as the difference between the observed and the predictable feed intake considering size and growth of the animal. It is extremely important to beef production systems due to its impact on the allocation of land areas to alternative agricultural production, animal methane emissions, food demand and cost of production. Global differential gene expression analysis between high and low RFI groups (HRFI and LRFI: less and more efficient, respectively) revealed 73 differentially expressed (DE) annotated genes in Longissimus thoracis (LT) muscle of Nelore steers. These genes are involved in the overrepresented pathways Metabolism of Xenobiotics by Cytochrome P450 and Butanoate and...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Genome-wide association studies; Quantitative trait locus; Gado de corte; Gene expression; Feed conversion; Beef cattle; Nellore.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1073482
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Genome scan revealed new pathways related to meat tenderness in Nelore beef cattle. Repositório Alice
TIZIOTO, P. L.; DECKER, J. E.; SCHNABEL, R. D.; MUDADU, M. A.; SILVA, F. L.; MOURÃO, G. B.; COUTINHO, L. L.; THOLON, P.; SONSTEGARD, T. S.; ROSA, A. N.; ALENCAR, M. M.; TULLIO, R. R.; MEDEIROS, S. R.; NASSU, R. T.; FEIJÓ, G. L. D.; SILVA, L. O. C.; TORRES, R. A.; SIQUEIRA, F.; HIGA, R. H.; TAYLOR, J. F.; REGITANO, L. C. de A..
A genome wide-association study (GWAS) for Warner-Bratzler shear force (WBSF) measured at different times of meat aging was conducted using genotype data from the Illumina BovineHD BeadChip to identify QTLs in Nelore cattle (n=442).
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Genoma; Gado de corte; Genome; Beef cattle; Nellore.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/969364
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Genome scan revealed new pathways related to meat tenderness in Nelore beef cattle. Repositório Alice
TIZIOTO, P. C.; DECKER, J. E.; SCHNABEL, R. D.; MUDADU, M. de A.; SILVA, F. L.; MOURÃO, G. B.; COUTINHO. L. L.; THOLON, P.; SONSTEGARD, T. S; ROSA, A. do N.; ALENCAR, M. M. de; TULLIO, R. R.; MEDEIROS, S. R.; NASSU, R. T.; FEIJO, G. L. D.; SILVA, L. O. C. da; SIQUEIRA, F.; HIGA, R. H.; TAYLOR, J. F.; REGITANO, L. C. de A..
2013
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Genome scan; Nellore; Meat tenderness.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/988848
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Genomics in the United States beef industry. Repositório Alice
ROFL, M. M.; DECKER, J. E.; McKAY, S. D.; TIZIOTO, P. C.; BRANHAM, K. A.; WHITACRE, L. K.; HOFF, J. L.; REGITANO, L. C. de A.; TAYLOR, J. F..
While genetic evaluation systems which combine performance records and pedigree data have been utilized n the beef industry forover four decades,the incorporation of genomic information into genetic evaluation, and the effective implementation of genomic tools with in the industry is relatively novel. Genomic technologies have been effectively deployed in the dairy, swine, and poultry industries;however, the beef industry possesses unique challenges for technology transfer. In this paper, we discuss the current limitations of genomic technologies and hindr0ances to the transfer of these technologies to the beef industry, while also considering opportunities for improved genomic and epigenomic tools needed to surmount barriers to technology adoption.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Beef cattle; Bovine; Genomics selection; Genetic evaluation.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1002780
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Global liver gene expression differences in Nelore steers with divergent residual feed intake phenotypes. Repositório Alice
TIZIOTO, P.; COUTINHO, L. L.; DECKER, J. E.; SCHNABEL, R. D.; ROSA, C. O.; OLIVEIRA, P. S. N.; SOUZA, M. M.; MOURÃO, G. B.; TULLIO, R. R.; CHAVES, A. S.; LANNA, D. P. D.; ZERLOTINI NETO, A.; MUDADU, M. A.; TAYLOR, J. F.; REGITANO, L. C. A..
Background: Efficiency of feed utilization is important for animal production because it can reduce greenhouse gas emissions and improve industry profitability. However, the genetic basis of feed utilization in livestock remains poorly understood. Recent developments in molecular genetics, such as platforms for genome-wide genotyping and sequencing, provide an opportunity to identify genes and pathways that influence production traits. It is known that transcriptional networks influence feed efficiency-related traits such as growth and energy balance. This study sought to identify differentially expressed genes in animals genetically divergent for Residual Feed Intake (RFI), using RNA sequencing methodology (RNA-seq) to obtain information from genome-wide...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Transcriptoma; Sequenciamento genético; Bioinformática; Bos indicus; RFI; Feed efficiency; Zebu; Feed conversion; Transcriptomics; Bioinformatics.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1034697
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Resolving the evolution of extant and extinct ruminants with hith-throughput phylogenomics. Repositório Alice
DECKER, J. E.; PIRES, J. C.; CONANT, G. C.; MCKAY, S. D.; HEATON, M. P.; CHEN, K.; COOPER, A.; VIKKI, J.; SEABURY, C. M.; CAETANO, A. R.; JOHNSON, G. D.; BRENNEMAN, R. A.; HANOTTE, O.; EGGERT, L. S.; WIENER, P.; KIM, J.-J.; KIM, K. S.; SONSTEGARD, T. S.; TASSELL, C. P. V.; NEIBERGS, H. L.; MCEWAN, J. C.; BRAUNING, R.; COUTINHO, L. L.; BABAR, M. E.; WILSON, G. A.; MCCLURE, M. C.; ROLF, M. M.; KIM, J. W.; SCHNABEL, R. D.; TAYLOR, J. F..
bitstream/item/178476/1/SP-19768-ID-31945.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Pecoran; Ancient DNA; Ruminant; Ruminante; Domestication.
Ano: 2009 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/577801
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Tissue tropism in host transcriptional response to members of the bovine respiratory disease complex. Repositório Alice
BEHURA, S. K.; TIZIOTO, P. C.; KIM, J.; GRUPIONI, N. V.; SEABURY, C. M.; SCHNABEL, R. D.; GERSHWIN, L. J.; VAN EEnenNAAM, A. L.; TOAF-FROSENSTEIN, R.; NEIBERGS, H. L.; REGITANO, L. C. de A.; TAYLOR, J. F..
Bovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens. We examined the global changes in mRNA abundance in healthy lung and lung lesions and in the lymphoid tissues bronchial lymph node, retropharyngeal lymph node, nasopharyngeal lymph node and pharyngeal tonsil collected at the peak of clinical disease from beef cattle experimentally challenged with either bovine respiratory syncytial virus, infectious bovine rhinotracheitis, bovine viral diarrhea virus, Mannheimia haemolytica or Mycoplasma bovis. We identified signatures of tissue-specific transcriptional responses indicative of tropism in the...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: MRNA; Bovinos de corte; BRD; Doença Respiratória; Gado de Corte; Beef cattle; Bovine respiratory disease.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1106292
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Variation in myogenic differentiation 1 mRNA abundance is associated with beef tenderness in Nelore cattle. Repositório Alice
TIZIOTO, P. C.; COUTINHO, L. L.; GASPARIN, G.; MALAGO JUNIOR, W.; DONATONI, F. A. B.; TULLIO, R. R.; NASSU, R. T.; TAYLOR, J. F.; REGITANO, L. C. de A..
The myogenic differentiation 1 gene (MYOD1) has a key role in skeletal muscle differentiation and composition through its regulation of the expression of several muscle-specific genes. We first used a general linear mixed model approach to evaluate the association of MYOD1 expression levels on individual beef tenderness phenotypes. MYOD1 mRNA levels measured by quantitative polymerase chain reactions in 136 Nelore steers were significantly associated (P ? 0.01) with Warner?Bratzler shear force, measured on the longissimus dorsi muscle after 7 and 14 days of beef aging. Transcript abundance for the muscle regulatory gene MYOD1 was lower in animals with more tender beef. We also performed a coexpression network analysis using whole transcriptome sequence...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Expressão gênica; Bos indicus; Qualidade da carne; MYOD1; SRF; Gado Nelore; Nellore.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1055157
Registros recuperados: 12
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