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| Garraud, O.; Diouf, A.; Longacre, S.; Kaslow, D.C.; Holder, A.A.; Dieye, A.; Tall, A.; Roussihon, C.; Trape, Jean-François; Rogier, C.; Perraut, R.; Mercereau-Puijalon, O.. |
| To investigate the potential influence of antigen (Ag) presentation on the immune response to MSP1 19, the 19 kDa C-terminal domain of the #Plasmodium falciparum$ MSP1 Ag, 3 recombinant MSP 19 Ags expressed in baculovirus, #E. coli$ and #Saccharomyces cerevisiae$ were used to stimulate in vitro peripheral blood mononuclear cells (PBMCS) from #P. falciparum$ immune adults with no recent history of clinical malaria. Donors were recruited in 2 senegalese villages (Dielmo and Ndiop), where malaria transmission is perennial and seasonal, respectively. Each PBMC preparation was stimulated with a range of concentrations of the 3 recombinant Ags (cleaved from carrier molecules when appropriate). Most subjects responded to at least 1 recombinant Ag (SI > 3 in... |
| Tipo: Text |
Palavras-chave: PALUDISME; VECTEUR; INFESTATION; IMMUNOLOGIE; ANTIGENE; AGENT PATHOGENE; TRANSMISSION; REPONSE IMMUNE; ANTIGENE RECOMBINANT; ANTIGENE MSP1. |
| Ano: 1996 |
URL: http://www.documentation.ird.fr/hor/fdi:010007002 |
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| Tall, A.. |
| Background information is presented of the importance of the artisanal fisheries sector in West Africa in terms of income and employment generation, foreign exchange earning and as a major supplier of animal protein to low income urban dwellers and the rural poor. Processing methodologies of smoking, salting/drying and fermentation is still traditional although improved technologies are being introduced and gradually adopted and coupled with a few semi-industrial processors to produce a final product with preferred tastes and market preferences. West Africa artisanal fisheries could benefit considerably from increased trade to the so called "ethnic market" in Europe, USA and other developed countries. Some key trading routes have been identified for the... |
| Tipo: Conference Material |
Palavras-chave: Development; Cured products; Tariff bariers; Fish trade channels; Artisanal sector; Small scale fishing; Artisanal fishing. |
| Ano: 2002 |
URL: http://hdl.handle.net/1834/745 |
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| Rogier, C.; Brau, R.; Tall, A.; Cisse, B.; Trape, Jean-François. |
| A 3 d shortened course of the quinine-quinidine-cinchonin association Quinimax (trademark) was compared to the usual 7 d regimen for routinely treating 462 acute uncomplicated #Plasmodium falciparum$ malaria attacks in 72 children under the age of 10 years in Dielmo, a holoendemic village in Senegal. 25 mg/kg Quinimax (trademark) salt daily, given in 3 equal doses, improved clinical status in 99.6% of the patients receiving the course and in all of those treated for 7 d. Even if the 3 d course did not systematically eliminate parasitaemia, reducing oral Quinimax (trademark) treatment of uncomplicated malaria from 7 to 3 d did not increase the recurrence of attacks, even among the youngest children. Both the quinine sensitivity of the Senegalese strains of... |
| Tipo: Text |
Palavras-chave: PALUDISME; CHIMIOPROPHYLAXIE; TRAITEMENT MEDICAL; SENSIBILITE RESISTANCE; EFFICACITE; ENFANT; QUININE; QUINIDINE; CINCHONINE; QUINIMAX. |
| Ano: 1996 |
URL: http://www.documentation.ird.fr/hor/fdi:010005230 |
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| Pradines, B.; Rogier, C; Fusai, T.; Tall, A.; Trape, Jean-François; Parzy, D.. |
| La sensibilité in vitro de 229 isolats de #Plasmodium falciparum$ prélevés dans la région de Fatick, Sénégal, a été étudiée vis-à-vis de 6 anti-paludiques classiques (chloroquine, cycloguanil, quinine, méfloquine, halofantrine et pyriméthamine) en utilisant le semi-microtest de Le Bras et Deloron dans sa version isotopique. Sur ces 229 souches, 39 % sont résistantes à la chloroquine (Cl 50 > 100 nM), 16 % au cycloguanil (Cl 50 > 500 nM), 1 % à la quinine (Cl 50 > 500 nM), 15 % à la méfloquine (Cl 50 > 20 nM), 10 % à l'halofantrine (Cl 50 > 5 nM) et 18 % à la pyriméthamine (Cl 50 > 2000 nM). On note en outre que 5 % des souches sont résistantes à la fois à la chloroquine et au cycloguanil. Une corrélation positive a été observée entre les... |
| Tipo: Text |
Palavras-chave: PALUDISME; AGENT PATHOGENE; SENSIBILITE RESISTANCE; TRAITEMENT MEDICAL; CHLOROQUINE; CYCLOGUANIL; QUININE; MEFLOQUINE; HALOFANTRINE; PYRIMETHAMINE. |
| Ano: 1996 |
URL: http://www.documentation.ird.fr/hor/fdi:010008028 |
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| Pradines, B.; Rogier, C.; Fusai, T.; Tall, A.; Trape, Jean-François; Doury, J.C.. |
| L'émergence de la chloroquino-résistance de #Plasmodium falciparum$ puis son extension à d'autres antimalariques ont été observées en Afrique. Cependant, nous ne disposons pour le Sénégal que de résultats fragmentaires. A la veille de la mise sur le marché de l'association chloroquine-proguanil, peu d'études sur la sensibilité d'isolats vis-à-vis de ces deux molécules ont été réalisées. La sensibilité in vitro de 85 isolats de #Plasmodium falciparum$ prélevés dans la région de Fatick au Sénégal, entre le 24 octobre et le 2 décembre 1995, a été étudiée vis-à-vis de cinq antimalariques classiques, la chloroquine, la cycloguanil, la quinine, la méfloquine et l'halofantrine en utilisant le semi-microtest isotopique. 29% des souches étaient résistantes à la... |
| Tipo: Text |
Palavras-chave: PALUDISME; AGENT PATHOGENE; SENSIBILITE RESISTANCE; CHIMIOPROPHYLAXIE; ETUDE COMPARATIVE; CHLOROQUINE; QUININE; CYCLOGUANIL; HALOFANTRINE; MEFLOQUINE. |
| Ano: 1996 |
URL: http://www.documentation.ird.fr/hor/fdi:010006534 |
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| Rogier, C.; Brau, R.; Tall, A.; Cisse, B.; Trape, Jean-François. |
| En cas de résistance de #Plasmodium falciparum$ aux amino-4-quinoléines et à la sulfadoxine-pyriméthamine, le traitement oral des accès palustres simples par la quinine peut avoir un intérêt en zone de forte endémie. La cure classique de 7 jours est cependant astreignante, relativement onéreuse et entraîne des effets secondaires (cinchonisme). Pour améliorer l'acceptabilité de ce traitement, nous avons comparé l'efficacité d'une cure courte de 3 jours par 25 mg/kg/jour de Quinimax (association de quinine, quinidine et cinchonine) à celle d'une cure de 7 jours au cours d'un essai thérapeutique randomisé portant sur 462 accès palustres simples à #Plasmodium falciparum$ chez 72 enfants âgés de moins de 10 ans. Le délai médian de guérison clinique avant la... |
| Tipo: Text |
Palavras-chave: PALUDISME; METHODE DE LUTTE; TRAITEMENT MEDICAL; EFFICACITE; QUININE. |
| Ano: 1995 |
URL: http://www.documentation.ird.fr/hor/fdi:010004249 |
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| Tall, A.. |
| World fisheries, which include fish and fishery products management, catches processing marketing and aquaculture, every year major fluctuations. Despite such variations, fishery products contribute significantly to human food consumption and constitute and important source of both employment, and income and had currency earnings, for a great number of countries and communities. |
| Tipo: Working Paper |
Palavras-chave: Fishery products; Fishery policy. |
| Ano: 2002 |
URL: http://hdl.handle.net/1834/380 |
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