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Effects of chronic heart disease on skeletal muscle fiber size BJMBR
Mattiello-Sverzut,A.C.; Chimelli,L.; Teixeira,S.; Pierre,M.; Oliveira,L..
Size changes in muscle fibers of subjects with chronic heart disease (CHD) have been reported, although a consensus has not been achieved. The aims of the present study were to investigate a possible association between CHD and fiber size changes in the brachial biceps compared to subjects without heart disease. Forty-six muscle samples were obtained in autopsies of individuals (13 to 84 years) without neuromuscular disorders, 19 (10 males and 9 females) with, and 27 (14 males and 13 females) without CHD. In all cases muscle sections were stained with hematoxylin and eosin and processed for the visualization of myofibrillar ATPase activity. The lesser diameter of type 1 and type 2 fibers was obtained tracing their outlines (at least 150 fibers of each type...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Morphometry; Brachial biceps; Chronic heart disease; Post mortem muscle; Type 1 fiber hypertrophy; Type 2 fiber hypertrophy.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000200019
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