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Association between molecular markers linked to the Leptin gene and weight gain in postpartum beef cows Ciência Rural
Almeida,Sabrina Esteves Matos; Almeida,Erik Amazonas de; Terra,Gustavo; Neves,Jairo Pereira; Gonçalves,Paulo Bayard Dias; Weimer,Tania de Azevedo.
Three short tandem repeats (STRs), BMS1074, BM1500, IDVGA-51, and three single nucleotide polymorphisms (SNPs), LEPSau3AI (A/B), LEPSau3AI (+/-) and LEPKpn2I linked to the LEP gene were investigated to verify associations with productive performance in postpartum cows of two beef cattle breeds, Aberdeen Angus (AA, n=98) and Charolais (C, n=83). After polymerase chain reaction, STRs were analyzed by vertical electrophoresis and SNPs in agarose gel after endonucleases cleavage. In AA herd 79% of BMS1074*151 carriers had a lower average daily weight gain (ADG) when compared with the population mean daily weight gain (103g), while 62% of BMS1074*151 non-carriers presented a higher ADG (P<0.01); AA animals with at least one BMS1074*151 allele showed a ADG...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptin; STRs; SNPs; Beef cattle; Weight gain; Post-partum.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782007000100033
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Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds Genet. Mol. Biol.
Almeida,Sabrina E.M.; Santos,Luciana B.S.; Passos,Daniel T.; Corbellini,Ângela O.; Lopes,Beatriz M.T.; Kirst,Cláudia; Terra,Gustavo; Neves,Jairo P.; Gonçalves,Paulo B.D.; Moraes,José C.F.; Weimer,Tania de Azevedo.
The genetic diversity of a single nucleotide polymorphism (SNP) at the exon 20 (T945M) of the leptin receptor gene (LEPR) and of three short tandem repeats (STRs BM7225, BMS694, and BMS2145) linked to LEPR was investigated in three beef cattle herds (Brangus Ibagé, Charolais, and Aberdeen Angus). A cheap and effective new method to analyze the T945M polymorphism in cattle populations was developed and the possible role of these polymorphisms in reproduction and weight gain of postpartum cows was evaluated. High levels of genetic diversity were observed with the average heterozygosity of STRs ranging from 0.71 to 0.81. No significant association was detected between LEPR markers and reproductive parameters or daily weight gain. These negative results...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Molecular markers; Genetic diversity; Cattle production; LEPR gene polymorphisms.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400013
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