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Experimental Study on the Changing Rules of Coal Fire Indictor Gases of the Whole Combustion Phases in Confined Space BABT
Lei,Baiwei; Wu,Bing; Wang,Xuyang.
ABSTRACT When the coal mine fire occurs, it is crucial to judge the fire combustion state by analyzing indicator gases concentration and changing trends of various gas ratios in order to formulate proper rescue measures. It's an effective methodology to estimate the changes of combustion state in coal mine fire accurately by the trends analysis of indicator gases and gas ratios independent of the external environment disturbs, such as air leakage and inner gases injection. However, there are few experimental researches about the changing rules of indicator gases and gas ratios at different combustion phases at present. Therefore, this paper has established a small-sized coal combustion experimental platform in confined space, on which the experimental...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coal combustion; Indicator gases; Gas ratios; Trend analysis.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000200704
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Hydrogen sulfide protects H9c2 cardiomyoblasts against H2O2-induced apoptosis BJMBR
Zhang,You En; Huang,Guang Qing; Wu,Bing; Lin,Xin Duo; Yang,Wen Zi; Ke,Zun Yu; Liu,Jie.
Reactive oxygen species (ROS) are highly reactive chemical species that may cause irreversible tissue damage, and play a critical role in cardiovascular diseases. Hydrogen sulfide (H2S) is a gasotransmitter that acts as a ROS scavenger with cardio-protective effects. In this study, we investigated the cytoprotective effect of H2S against H2O2-induced apoptosis in cardiomyocytes. H9c2 rat cardiomyoblasts were treated with H2S (100 μM) 24 h before challenging with H2O2 (100 μM). Apoptosis was then assessed by annexin V and PI, and mitochondrial membrane potential was measured using a fluorescent probe, JC-1. Our results revealed that H2S improved cell viability, reduced the apoptotic rate, and preserved mitochondrial membrane potential. An increased Bcl-2 to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Reactive oxygen species; ROS; Hydrogen sulfide; H2O2-induced apoptosis; Cardiomyocytes.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000400608
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SAD-B modulates epileptic seizure by regulating AMPA receptors in patients with temporal lobe epilepsy and in the PTZ-induced epileptic model BJMBR
Li,Rong; He,Miaoqing; Wu,Bing; Zhang,Peng; Zhang,Qinbin; Chen,Yangmei.
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the predominant mediators of glutamate-induced excitatory neurotransmission. It is widely accepted that AMPA receptors are critical for the generation and spread of epileptic seizure activity. Dysfunction of AMPA receptors as a causal factor in patients with intractable epilepsy results in neurotransmission failure. Brain-specific serine/threonine-protein kinase 1 (SAD-B), a serine-threonine kinase specifically expressed in the brain, has been shown to regulate AMPA receptor-mediated neurotransmission through a presynaptic mechanism. In cultured rat hippocampal neurons, the overexpression of SAD-B significantly increases the frequency of miniature excitatory postsynaptic currents...
Tipo: Info:eu-repo/semantics/article Palavras-chave: SAD-B; AMPA receptor; Temporal lobe epilepsy; PTZ.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000400602
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