Sabiia Seb
PortuguêsEspañolEnglish
Embrapa
        Busca avançada

Botão Atualizar


Botão Atualizar

Ordenar por: RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 88
Primeira ... 12345 ... Última
Imagem não selecionada

Imprime registro no formato completo
A comparative study of aging of the elastic fiber system of the diaphragm and the rectus abdominis muscles in rats BJMBR
Rodrigues,C.J.; Rodrigues Junior,A.J..
In the present study the age-related changes of the striated muscle elastic fiber system were investigated in the diaphragm and rectus abdominis muscles of 1-, 4-, 8- and 18-month-old rats. The activation patterns of these muscles differ in that the diaphragm is regularly mobilized tens of times every minute during the entire life of the animal whereas the rectus abdominis, although mobilized in respiration, is much less and more irregularly activated. The elastic fibers were stained by the Verhoeff technique for mature elastic fibers. Weigert stain was used to stain mature and elaunin elastic fibers, and Weigert-oxone to stain mature, elaunin and oxytalan elastic fibers. The density of mature and elaunin elastic fibers showed a progressive increase with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; Elastin; Extracellular matrix; Diaphragm; Rectus abdominis.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001200008
Imagem não selecionada

Imprime registro no formato completo
Acute exercise performed close to the anaerobic threshold improves cognitive performance in elderly females BJMBR
Córdova,C.; Silva,V.C.; Moraes,C.F.; Simões,H.G.; Nóbrega,O.T..
The objective of the present study was to compare the effect of acute exercise performed at different intensities in relation to the anaerobic threshold (AT) on abilities requiring control of executive functions or alertness in physically active elderly females. Forty-eight physically active elderly females (63.8 ± 4.6 years old) were assigned to one of four groups by drawing lots: control group without exercise or trial groups with exercise performed at 60, 90, or 110% of AT (watts) and submitted to 5 cognitive tests before and after exercise. Following cognitive pretesting, an incremental cycle ergometer test was conducted to determine AT using a fixed blood lactate concentration of 3.5 mmol/L as cutoff. Acute exercise executed at 90% of AT resulted in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; Alert; Anaerobic threshold; Exercise; Executive functions; Response time test.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000500010
Imagem não selecionada

Imprime registro no formato completo
Administering ascorbic acid to rats undergoing ageing processes: effects on myosin-V immunoreactive myenteric neurons Anais da ABC (AABC)
Mello,Sônia A.; Marese,Angélica C.M.; Brancalhão,Rose M.C.; Zanoni,Jacqueline N.; Natali,Maria Raquel M..
During the ageing process the enteric nervous system undergoes morphofunctional changes, such as enteric neurodegeneration. Neuronal death can be attributed to increase radicals free, and ascorbic acid (AA), known antioxidant, could minimize damage cause by oxidative stress. The objective of this study is to analyse the behaviour of morphoquantative myenteric neurons in the duodenum of adult Wistar rats with aged 90 (C90), 345 (E345) and 428 (E428) days, as well as animals of the same age who received ascorbic acid supplementation for 120 days (EA345 and EA428). Whole-mount preparations of muscle layer from the duodenum of the animals were immunostained by the method myosin V. 80 microscopic fields were quantified (14.8 mm2/animal) and measured 100...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; Antioxidant; Enteric nervous system; Immunohistochemistry.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000100337
Imagem não selecionada

Imprime registro no formato completo
Age Effect in the Morphological Traits Performance for Sex Determination in Human Skulls and Mandibles International Journal of Morphology
Suazo Galdames,Iván; Zavando,Daniela.
In this study we tested the hypothesis that diagnostic performance of the morphological indicators for sexual dimorphism are reduced as they are applied in skull and mandibles of older subjects. We used 275 adult human skulls, 250 of these with mandible, all subjects with sex and age registry. Sixteen classic morphological indicators of sexual dimorphism were evaluated, this information was compared with the registry and results noted in terms of precision. The best general performance of morphological indicators of sexual dimorphism were recorded in the 31 - 40 and 61 - 70 years, age range groups. Lowest precision ws recorded in the group corresponding to subjects between 21 ­ 30 years. Our results do not support the proposed hypothesis and suggest a...
Tipo: Journal article Palavras-chave: Sexual dimorphism; Sex determination; Aging; Age; Skull.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100053
Imagem não selecionada

Imprime registro no formato completo
Age related interaction of dopamine and serotonin synthesis in striatal synaptosomes Biocell
Messripour,Manoochehr; Mesripour,Azadeh.
Tyrosine hydroxylase and tryptophan hydroxylase are key rate limiting enzymes in the biosyn-thesis of dopamine and serotonin, respectively. Since both enzymes are active in striatum, and affected by age, this study was undertaken to investigate interaction between dopamine and serotonin synthesis in brain striatal synaptosomes of aging rat. Male Wistar rats (3 and 30 month old) were killed by decapitation and brain striatal synaptosomes were prepared by discontinuous Ficoll/sucrose gradient technique. Synaptosomes were incubated in the presence of added pargiline (monoamineoxidase inhibitor), dopamine or serotonin synthesized during 25 min was measured by HPLC, employing electrochemical detection. Dopamine synthesis in synaptosomes prepared from young...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; Nerve ending; Neurotransmitter; Tyrosine hydroxylase; Tryptophan hydroxylase.
Ano: 2013 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452013000200001
Imagem não selecionada

Imprime registro no formato completo
Age-related Changes in DNA Methylation Status of hTERT Gene Promoter of Oral Epithelial Cells BABT
Bezerra,Stephane Flaviane de Oliveira; Costa,Ludimila de Araújo; Freitas,Priscylla Alves Nascimento de; Oliveira,Naila Francis Paulo de.
The purpose of this study was to investigate the effect of aging on the DNA methylation status of two genes involved in tumorigenesis (telomerase gene hTERT and DNA repair gene- MLH1) and one in metabolism (methylenetetrahydrofolate reductase gene- MTHFR) in oral epithelial cells. DNA methylation analysis was performed by Methylation Sensitive Restriction Enzymes (MSRE) of healthy oral epithelial cells of child (6-10 years, n=21), young (20-25 years, n=19) and elderly (over 60 years, n=25). The results for the hTERT gene showed significant variation in the methylation frequency at CpG dinucleotides among the groups (p=0.0001), with the methylated condition more frequently in children and young people. In relation to MLH1 and MTHFR, no differences were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epigenetic; DNA methylation; Aging; DNA repair; Telomerase; MTHFR.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000100082
Imagem não selecionada

Imprime registro no formato completo
Aging alters the production of iNOS, arginase and cytokines in murine macrophages BJMBR
Cecílio,C.A.; Costa,E.H.; Simioni,P.U.; Gabriel,D.L.; Tamashiro,W.M.S.C..
The limited amount of information on the primary age-related deficiencies in the innate immune system led us to study the production of inducible nitric oxide synthase (iNOS), arginase, and cytokines in macrophages of young (8 weeks old) and old (72 weeks old) female BALB/c mice. We first evaluated iNOS and arginase inducers on peritoneal (PMΦ) and bone marrow-derived (BMMΦ) macrophages of young BALB/c and C57BL/6 mice, and then investigated their effects on macrophages of old mice. Upon stimulation with lipopolysaccharide (LPS), resident and thioglycolate-elicited PMΦ from young mice presented higher iNOS activity than those from old mice (54.4%). However, LPS-stimulated BMMΦ from old mice showed the highest NO levels (50.1%). Identical NO levels were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; INOS; Arginase; Cytokines; Murine macrophages; Inflammatory stimuli.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000700010
Imagem não selecionada

Imprime registro no formato completo
Aging and immunoglobulin isotype patterns in oral tolerance BJMBR
Faria,A.M.C.; Ficker,S.M.; Speziali,E.; Menezes,J.S.; Stransky,B.; Verdolin,B.A.; Lahmann,W.M.; Rodrigues,V.S.; Vaz,N.M..
In the present review we address oral tolerance as an important biological phenomenon and discuss how it is affected by aging. Other factors such as frequency of feeding and previous digestion of the antigen also seem to influence the establishment of oral tolerance. We also analyze immunoglobulin isotypes of specific antibodies formed by tolerant and immunized animals of different ages submitted to different conditions of oral antigen administration. Isotypic patterns were studied as a parameter for assessing the pathways of B and T cell interactions leading to antibody production
Tipo: Info:eu-repo/semantics/article Palavras-chave: Oral tolerance; Aging; Isotypes; Gut; Mucosa.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000100005
Imagem não selecionada

Imprime registro no formato completo
Aging, neurocognitive impairment and adherence to antiretroviral therapy in human immunodeficiency virus-infected individuals BJID
Pinheiro,Cezar Arthur Tavares; Souza,Luciano Dias de Mattos; Motta,Janaína Vieira dos Santos; Kelbert,Evelin Franco; Martins,Clarissa de Souza Ribeiro; Souza,Marília Silva de; Pinheiro,Karen Amaral Tavares; Coelho,Fábio Monteiro da Cunha; Pinheiro,Ricardo Tavares.
ABSTRACT Background/objective: There is an increasing number of older patients with human immunodeficiency virus infection due to the success of antiretroviral therapy, the improved prognosis and life expectancy of patients, and the higher number of new infections among older individuals. The main objective of the present study was to compare the characteristics of older human immunodeficiency virus patients with those of younger patients. Materials and methods: We conducted a cross-sectional study with human immunodeficiency virus-infected patients who were treated at the Specialized Care Service (Serviço de Assistência Especializada) for human immunodeficiency virus/AIDS in the city of Pelotas, South Brazil. Sociodemographic information as well as data...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; HIV; Neurocognitive impairment; Adherence.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600599
Imagem não selecionada

Imprime registro no formato completo
Aging reduces the primary humoral response and the in vitro cytokine production in mice BJMBR
Simioni,P.U.; Costa,E.H.; Tamashiro,W.M.S.C..
Aging is accompanied by a decrease in several physiological functions that make older individuals less responsive to environmental challenges. In the present study, we analyzed the immune response of female BALB/c mice (N = 6) of different ages (from 2 to 96 weeks) and identified significant age-related alterations. Immunization with hapten-protein (trinitrophenyl-bovine serum albumin) conjugates resulted in lower antibody levels in the primary and secondary responses of old mice (72 weeks old). Moreover, young mice (2, 16, and 32 weeks old) maintained specific antibodies in their sera for longer periods after primary immunization than did old mice. However, a secondary challenge efficiently induced memory in old mice, as shown by the increased antibody...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; Cytokines; Antibody; Proliferation; T cell response; T cell subsets.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800012
Imagem não selecionada

Imprime registro no formato completo
Aging with HIV: a practical review BJID
Cardoso,Sandra Wagner; Torres,Thiago Silva; Santini-Oliveira,Marilia; Marins,Luana Monteiro Spindola; Veloso,Valdiléa Gonçalves; Grinsztejn,Beatriz.
The worldwide elderly population is expected to grow by an additional 694 million people by 2025. By that time, there will be approximately two billion elderly people in the world, most of whom (80%) will be living in developing countries. Based on recent estimates, this population will number over 40 million in 2030 in Brazil and a consequent increase in governmental spending for this population can be expected. Since highly active antiretroviral therapy became available in the mid-1990s, the life expectancy of people living with HIV has increased significantly. Approximately 12 million life years were added to the world between 1996 and 2008 as a consequence of wider access to highly active antiretroviral therapy. In Brazil, the incidence of AIDS among...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; AIDS; Aging; Elderly; Brazil; Comorbidity; HAART.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000400013
Imagem não selecionada

Imprime registro no formato completo
Aging with HIV: an overview of an urban cohort in Rio de Janeiro (Brazil) across decades of life BJID
Torres,Thiago Silva; Cardoso,Sandra Wagner; Velasque,Luciane de Souza; Marins,Luana Monteiro Spindola; Oliveira,Marília Santini de; Veloso,Valdilea Gonçalves; Grinsztejn,Beatriz.
The introduction of highly active antiretroviral therapy during the 1990s was crucial to the decline in the rates of morbidity and death related to the acquired immunodeficiency syndrome (AIDS) and turned human immunodeficiency virus (HIV) infection into a chronic condition. Consequently, the HIV/AIDS population is becoming older. The aim of this study was to describe the immunological, clinical and comorbidity profile of an urban cohort of patients with HIV/AIDS followed up at Instituto de Pesquisa Clinica Evandro Chagas, Oswaldo Cruz Foundation in Rio de Janeiro, Brazil. Retrospective data from 2307 patients during January 1st, 2008 and December 31st, 2008 were collected. For continuous variables, Cuzick's non-parametric test was used. For categorical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; AIDS; Aging; Elderly; Brazil; Comorbidity; HAART.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300004
Imagem não selecionada

Imprime registro no formato completo
Alternative mitochondrial functions in cell physiopathology: beyond ATP production BJMBR
Kowaltowski,A.J..
It is well known that mitochondria are the main site for ATP generation within most tissues. However, mitochondria also participate in a surprising number of alternative activities, including intracellular Ca2+ regulation, thermogenesis and the control of apoptosis. In addition, mitochondria are the main cellular generators of reactive oxygen species, and may trigger necrotic cell death under conditions of oxidative stress. This review concentrates on these alternative mitochondrial functions, and their role in cell physiopathology.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mitochondrial permeability transition; Uncoupling proteins; Alternative oxidase; Cardioprotection; Free radicals; Aging.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000200014
Imagem não selecionada

Imprime registro no formato completo
Application of atomic force microscopy in the analysis of time since deposition (TSD) of red blood cells in bloodstains: a forensic analysis. Repositório Alice
CAVALCANTI, D. R.; SILVA, L. P. da.
bitstream/item/201467/1/1-s2.0-S0379073818308387-main.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Red blood cells; Bloodstains; Aging; Time since deposition (TSD); Criminal analysis; Atomic force microscopy.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1111783
Imagem não selecionada

Imprime registro no formato completo
Assessing negative priming by attended distractors in a paper-and-pencil task BJMBR
Rosin,F.M..
The paper-and-pencil digit-comparison task for assessing negative priming (NP) was introduced, using a referent-size-selection procedure that was demonstrated to enhance the effect. NP is indicated by slower responses to recently ignored items, and proposed within the clinical-experimental framework as a major cognitive index of active suppression of distracting information, critical to executive functioning. The digit-comparison task requires circling digits of a list with digit-asterisk pairs (a baseline measure for digit-selection), and the larger of two digits in each pair of the unrelated (with different digits in successive digit-pairs) and related lists (in which the smaller digit subsequently became a target). A total of 56 students (18-38 years)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Negative priming; Selective attention; Paper-and-pencil tasks; Aging; Executive function.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000800004
Imagem não selecionada

Imprime registro no formato completo
Association of apolipoprotein E polymorphism in late-onset Alzheimer's disease and vascular dementia in Brazilians BJMBR
Souza,D.R.S.; De Godoy,M.R.; Hotta,J.; Tajara,E.H.; Brandão,A.C.; Pinheiro Júnior,S.; Tognola,W.A.; Dos Santos,J.E..
The genetic basis for dementias is complex. A common polymorphism in the apolipoprotein E (APOE) gene is considered to be the major risk factor in families with sporadic and late-onset Alzheimer's disease as well as in the general population. The distribution of alleles and genotypes of the APOE gene in late-onset Alzheimer's disease (N = 68), other late-life dementias (N = 39), and in cognitively normal controls (N = 58) was determined, as also was the risk for Alzheimer's disease associated with the epsilon4 allele. Peripheral blood samples were obtained from a total of 165 individuals living in Brazil aged 65-82 years. Genomic DNA was amplified by the polymerase chain reaction and the products were digested with HhaI restriction enzyme. APOE epsilon2...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Alzheimer's disease; Vascular dementia; Dementia; Apolipoprotein E; Aging; Genetic polymorphisms.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000700013
Imagem não selecionada

Imprime registro no formato completo
Autonomic modulation of heart rate of young and postmenopausal women undergoing estrogen therapy BJMBR
Neves,V.F.C.; Silva de Sá,M.F.; Gallo Jr.,L.; Catai,A.M.; Martins,L.E.B.; Crescêncio,J.C.; Perpétuo,N.M.; Silva,E..
The aim of the present study was to determine whether estrogen therapy (ET) reduces alterations of the autonomic control of heart rate (HR) due to hypoestrogenism and aging. Thirteen young (24 ± 2.6 years), 10 postmenopausal (53 ± 4.6 years) undergoing ET (PM-ET), and 14 postmenopausal (56 ± 2.6 years) women not undergoing ET (PM) were studied. ET consisted of 0.625 mg/day conjugated equine estrogen. HR was recorded continuously for 8 min at rest in the supine and sitting positions. HR variability (HRV) was analyzed by time (SDNN and rMSSD indices) and frequency domain methods. Power spectral components are reported as normalized units (nu) at low (LF) and high (HF) frequencies, and as LF/HF ratio. Intergroup comparisons: SDNN index was higher in young...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Heart rate variability; Aging; Menopause; Estrogen therapy.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000400007
Imagem não selecionada

Imprime registro no formato completo
Baroreflex sensitivity in frailty syndrome BJMBR
Buto,M.S.S.; Catai,A.M.; Vassimon-Barroso,V.; Gois,M.O.; Porta,A.; Takahashi,A.C.M..
Frailty is related to a decrease in the physiological reserves, which causes difficulties in maintaining homeostasis. An example of physiological mechanisms for cardiovascular homeostasis is the baroreflex. The aim of this study was to compare baroreflex among frail, prefrail, and nonfrail individuals, in supine and orthostatic positions. Community-dwelling older adults were evaluated and categorized into frail, prefrail, or nonfrail groups, according to frailty phenotype. The RR interval (RRi) and systolic blood pressure (SBP) series were recorded for 15 min in the supine and 15 min in the orthostatic positions. Mean and variance of RRi and SBP, and baroreflex evaluated by phase, gain (α), and coherence (K2) were determined. A two-way repeated measures...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Baroreflex; Autonomic nervous system; Aging; Frailty.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000400602
Imagem não selecionada

Imprime registro no formato completo
Benefits of caloric restriction in the myenteric neuronal plasticity in aging rats Anais da ABC (AABC)
PEREIRA,JOICE N.B.; MARI,RENATA B.; STABILLE,SANDRA R.; FARIA,HAROLDO G. DE; MOTA,THAIS F.M.; FERREIRA,WALTER M..
Aging is a biologic process characterized by progressive damage of structures and functions of organic systems. In gastrointestinal tract, it can involve enteric nervous system, which plays an important role in digestion and absorption of nutrients, causing hastening of intestinal transit thus reducing its absorptive function. Caloric restriction has been used in several studies with the intention of delaying deleterious effects of aging. This study aimed to evaluate the effects of caloric restriction on myenteric neurons of ileum by aging in rats. 30 Wistar rats were grouped as follows: GI (animals aged 6 months fed with normal diet), GII (animals aged 18 months fed with normal diet) and GIII (animals aged 18 months subject to 31% of caloric restriction)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; Caloric restriction; Myenteric plexus; Small intestine.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301471
Imagem não selecionada

Imprime registro no formato completo
Blood pressure, heart rate and its autonomic modulation in malnourished rats at different ages Biological Sciences
Sant’Helena, Bruna da Rosa Maggi; Brasileiro-Santos, Maria do Socorro; Falcão, Elis Pereira; Duarte, Denia Palmeira Fittipaldi; Pontes Filho, Nicodemos Telles de; Costa, Carlos Peres da.
Malnutrition is responsible for a number of alterations that occur in the organism, including alterations in the cardiovascular system. We hypothesize that long periods of malnutrition occurring after weaning may also be responsible for alterations in the cardiovascular system. Wistar rats were separated into the two following experimental groups: a labina® diet-fed control group (CG) and a malnourished group (MG), fed a multi-deficient diet. Results showed that the mg presented significantly lower body weight (p < 0.001) in rats of all ages, higher heart rate (HR) (p < 0.05) when rats were 3, 4 and 5 months old and lower HR in rats from 6 to 9 months of age, in relation to the CG. Spectral analysis showed a significant increase in the low...
Tipo: Info:eu-repo/semantics/article Palavras-chave: 2.07.00.00-8; Aging; Multi-deficient diet; Eletrocardiography; Spectral analysis morphology of the ventricles Fisiologa.
Ano: 2014 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/21482
Registros recuperados: 88
Primeira ... 12345 ... Última
 

Empresa Brasileira de Pesquisa Agropecuária - Embrapa
Todos os direitos reservados, conforme Lei n° 9.610
Política de Privacidade
Área restrita

Embrapa
Parque Estação Biológica - PqEB s/n°
Brasília, DF - Brasil - CEP 70770-901
Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco

Valid HTML 4.01 Transitional