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A new coumarin derivative, 4-acetatecoumarin, with antifungal activity and association study against Aspergillus spp. BJM
Guerra,Felipe Q.S.; Araújo,Rodrigo S.A.; Sousa,Janiere P.; Silva,Viviane A.; Pereira,Fillipe O.; Mendonça-Junior,Francisco J.B.; Barbosa-Filho,José M.; Pereira,Julio Abrantes; Lima,Edeltrudes O..
Abstract Fungal infections have become a concern for health professionals, and the emergence of resistant strains has been reported for all known classes of antifungal drugs. Among the fungi causing disease, we highlight those that belong to the genus Aspergillus. For these reasons, the search for new antifungals is important. This study examines the effects of a coumarin derivative, 4-acetatecoumarin (Cou-UMB16) both alone and together with antifungal drugs, and its mode of action against Aspergillus spp. Cou-UMB16 was tested to evaluate its effects on mycelia growth, and germination of Aspergillus spp. fungal conidia. We investigated its possible action on cell walls, on the cell membrane, and also the capacity of this coumarin derivative to enhance the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coumarin; Antifungal activity; A. flavus; A. fumigatus; Mode of action.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000200407
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Actinobactérias como agentes de controle biológico de fitopatógenos de trigo. Repositório Alice
VENTURA, J. P.; CASTELIANI, A. G. B.; VARGAS HOYOS, H. A.; SANTOS, S. N.; MELO, I. S. de.
Resumo: O trigo (Triticum aestivum L) constitui uma das principais culturas de importância agrícola para o Brasil. Contudo, a ocorrência de doenças como a brusone, tem limitado a produtividade dessa cultura nas regiões produtoras. Desse modo, o objetivo desse trabalho foi avaliar o potencial de uma linhagem Streptomyces sp. CMAA 1647, uma actinobacteria, no controle biológico de fungos fitopatogênicos, principalmente, Pyricularia grisea, agente causal da brusone. A linhagem modelo deste trabalho, Streptomyces sp. CMAA 1647, foi isolada a partir de solos supressivos à brusone e previamente selecionada por inibir o crescimento do agente causal. O potencial de antagonismo da linhagem CMAA 1647 foi avaliado pela técnica de pareamento direto contra os seguintes...
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Solos supressivos; Atividade antifúngica; Tratamento de sementes; Antifungal activity; Germination potential; Brusone; Doença de planta; Controle biológico; Trigo; Tratamento de semente; Streptomyces; Suppressive soils; Antifungal agents; Seed treatment; Suppressive soils.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1105031
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Alternative Control of Plant Pathogen Fungi Through Ethanolic Extracts of Avocado Seeds (Persea Americana Mill.) BABT
Fagundes,Miriã Cristina Pereira; Oliveira,Adelson Francisco de; Carvalho,Vicente Luiz de; Ramos,José Darlan; Santos,Verônica Andrade dos; Rufini,José Carlos Moraes.
ABSTRACT The aim of this study was to evaluate the antifungal action of ethanolic extracts of avocado seeds, by conducting two experiments in the laboratory of plant pathology of EPAMIG SUL/Lavras, MG, Brazil, in a completely randomized design with three replicates. The first consisted of the following treatments ('Breda' 3%, 'Breda' 2%, 'Margarida' 3%, 'Margarida' 2%, Control, and Ethanol) testing its inhibitory effect on two fungal species (Colletotrichum gloeosporioides and Monilinia fructicola) and the second consisted of different concentrations of extracts (0%, 0.25%, 0.50%, 0.75%, 1.0%, 1.5%, and 2.0%) on the fungus F fructicola. The evaluations were performed at three times (7, 14, and 21 days of incubation) by measurements of the mycelial diameter...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antifungal activity; Colletotrichum gloeosporioides; Monilinia fructicola; Postharvest.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100204
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Antibacterial and antifungal activities of fatty acid methyl esters of the blind-your-eye mangrove from India BJM
Agoramoorthy,G.; Chandrasekaran,M.; Venkatesalu,V.; Hsu,M.J..
Fatty acids are widely occurring in natural fats and dietary oils and they are known to have antibacterial and antifungal properties. However, little is known on the antibacterial and antifungal properties of the blind-your-eye mangrove (Excoecaria agallocha) and this study for the first time determines the fatty acid composition and the antibacterial and antifungal activities of Fatty Acid Methyl Esters (FAME) of the blind-your-eye mangrove plant found along the coastal areas of south India.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Blind-your-eye mangrove; Excoecaria agallocha; Antibacterial activity; Antifungal activity; Fatty acid methyl esters.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000400028
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Antifungal Activity of Aerial Parts of Cenchrus pennisetiformis Against Fusarium oxysporum f. sp. lycopersici Planta Daninha
KHURSHID,S.; JAVAID,A.; SHOAIB,A.; JAVED,S.; QAISAR,U..
ABSTRACT: Antifungal potential of aerial parts of an allelopathic grass Cenchrus pennisetiformis (Hochst. & Steud.) Wipff. was evaluated against Fusarium oxysporum f. sp. lycopersici Snyder & Hansen, a fungal pathogen causing wilt disease in tomato (Solanum lycopersicum L.). Different concentrations (1% to 6%) of methanolic leaf, stem and inflorescence extract of the grass significantly reduced fungal biomass by 40-88%, 13-89%, and 26-76%, respectively. Methanolic shoot (leaf + stem) extract was fractionated using four organic solvents viz. n-hexane, chloroform, ethyl acetate and n-butanol. All the sub-fractions of methanolic shoot extract showed remarkable antifungal potential to variable extents. Different concentrations (1.56-200 mg mL-1) of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antifungal activity; GC-MS analysis; Methanolic extracts.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582018000100223
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Antifungal activity of bacterial strains from the rhizosphere of Stachytarpheta crassifolia. Repositório Alice
SANTOS, S. N.; OLIVEIRA, L. K. X.; MELO, I. S. de; VELOSO, E. da S.; ROQUE, M. R. de A..
This study evaluated the antifungal action of biomolecules produced from the secondary metabolism of bacterial strains found in the rhizosphere of semi arid plants against human pathogenic Candida albicans. Crude extracts were obtained using ethyl acetate as an organic solvent and the bioactivity was assessed with a bioautography technique. The results showed that bacterial strains, Alcaligenes faecalis MRbS12 and Bacillus cereus MRbS26, had compounds with antifungal bioactivity. The largest inhibition zones for both compounds were located on spots with Rf values below 0.500, indicating that the molecules possibly had polar characteristics. These results suggested that microorganisms found in the environment could have bioprospecting potential.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Biomolecules; Bioautoghaphy; Antifungal activity; Alcaligenes faecalis; Bacillus cereus; Candida albicans; Bactéria; Rizosfera; Controle biológico; Rhizobiales; Antifungal agents; Biological control.
Ano: 2011 URL: http://www.alice.cnptia.embrapa.br/handle/doc/898255
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ANTIFUNGAL ACTIVITY OF Cirsium arvense EXTRACTS AGAINST PHYTOPATHOGENIC FUNGUS Macrophomina phaseolina Planta Daninha
BANARAS,S.; JAVAID,A.; SHOAIB,A.; AHMED,E..
ABSTRACT Leaves, stems, roots and inflorescence of the asteraceous weed Circium arvense were extracted in methanol for two weeks. Methanol was evaporated in a rotary evaporator. Different concentrations (1, 2, 3, 4 and 5%) of methanolic extracts were prepared, and their antifungal activities were studied against Macrophomina phaseolina, using malt extract broth as growth medium. In general, extracts of all plant parts showed antifungal activities to variable extents. The highest antifungal activity occurred due to methanolic extract of leaves, followed by stem and root extracts, resulting in 10-74%, 6-57% and 11-39% reduction in fungal biomass over control, respectively. Inflorescence extract showed the least antifungal activity, resulting in 2-30%...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antifungal activity; Asteraceous weed; Cirsium arvense; Macrophomina phaseolina.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582017000100216
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Antifungal activity of essential oil isolated from Ocimum gratissimum L. (eugenol chemotype) against phytopathogenic fungi BABT
Faria,Terezinha de Jesus; Ferreira,Rafael Sottero; Yassumoto,Lidiane; Souza,José Roberto Pinto de; Ishikawa,Noemia Kazue; Barbosa,Aneli de Melo.
An investigation of antifungal activity of the essential oil obtained by steam-distillation (1.1% w/w) of the aerial parts of Ocimum gratissimum and of an ethanolic extract from the steam-distillation residue was carried out using the agar diffusion method. The results revealed that the essential oil inhibited the growth of all fungi tested, including the phytopathogens, Botryosphaeria rhodina, Rhizoctonia sp. and two strains of Alternaria sp., while the extract from the residue was inactive. The essential oil was subjected to TLC bioautography used to detect fungitoxic constituents. The compound that showed antifungal activity was isolated and identified as eugenol. GC/MS analysis showed that eugenol was the main constituent of the essential oil studied....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ocimum gratissimum; Antifungal activity; Eugenol; Phytopathogenic fungi.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000700002
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Antifungal activity of extracts from Piper aduncum leaves prepared by different solvents and extraction techniques against dermatophytes Trichophyton rubrum and Trichophyton interdigitale BJM
Santos,Maximillan Leite; Magalhães,Chaiana Froés; Rosa,Marcelo Barcellos da; Santos,Daniel de Assis; Brasileiro,Beatriz Gonçalves; Carvalho,Leandro Machado de; Silva,Marcelo Barreto da; Zani,Carlos Leomar; Siqueira,Ezequias Pessoa de; Peres,Rodrigo Loreto; Andrade,Anderson Assunção.
The effects of different solvents and extraction techniques upon the phytochemical profile and anti-Trichophyton activity of extracts from Piper aduncum leaves were evaluated. Extract done by maceration method with ethanol has higher content of sesquiterpenes and antifungal activity. This extract may be useful as an alternative treatment for dermatophytosis.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antifungal activity; Piper aduncum L.; Dermatophytes; Trichophyton; Extraction techniques.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400035
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Antifungal activity of five species of Polygala BJM
Johann,Susana; Mendes,Beatriz G; Missau,Fabiana C; Resende,Maria A. de; Pizzolatti,Moacir G.
Crude extracts and fractions of five species of Polygala - P. campestris, P. cyparissias, P. paniculata, P. pulchella and P. sabulosa - were investigated for their in vitro antifungal activity against opportunistic Candida species, Cryptococcus gattii and Sporothrix schenckii with bioautographic and microdilution assays. In the bioautographic assays, the major extracts were active against the fungi tested. In the minimal concentration inhibitory (MIC) assay, the hexane extract of P. paniculata and EtOAc fraction of P. sabulosa showed the best antifungal activity, with MIC values of 60 and 30 µg/mL, respectively, against C. tropicalis, C. gattii and S. schenckii. The compounds isolated from P. sabulosa prenyloxycoumarin and 1,2,3,4,5,6-hexanehexol displayed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Polygalaceae; Polygala species; Antifungal activity; Rutin; Α-spinasterol.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000300027
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Antifungal activity of metabolites of the endophytic fungus Trichoderma brevicompactum from garlic BJM
Shentu,Xuping; Zhan,Xiaohuan; Ma,Zheng; Yu,Xiaoping; Zhang,Chuanxi.
The endophytic fungus strain 0248, isolated from garlic, was identified as Trichoderma brevicompactum based on morphological characteristics and the nucleotide sequences of ITS1-5.8SITS2 and tef1. The bioactive compound T2 was isolated from the culture extracts of this fungus by bioactivity-guided fractionation and identified as 4β-acetoxy-12,13-epoxy-Δ9-trichothecene (trichodermin) by spectral analysis and mass spectrometry. Trichodermin has a marked inhibitory activity on Rhizoctonia solani, with an EC50 of 0.25 µgmL-1. Strong inhibition by trichodermin was also found for Botrytis cinerea, with an EC50 of 2.02 µgmL-1. However, a relatively poor inhibitory effect was observed for trichodermin against Colletotrichum lindemuthianum (EC50 = 25.60 µgmL-1)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Trichoderma brevicompactum; Garlic; Endophytic fungus; Trichodermin; Antifungal activity.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000100036
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Antifungal activity of nanoemulsions encapsulating oregano (Origanum vulgare) essential oil: in vitro study and application in Minas Padrão cheese BJM
Bedoya-Serna,Carolina M.; Dacanal,Gustavo C.; Fernandes,Andrezza M.; Pinho,Samantha C..
ABSTRACT The objective of this study was to evaluate the antifungal activity of nanoemulsions encapsulating essential oil of oregano (Origanum vulgare), both in vitro and after application on Minas Padrão cheese. Nanodispersions were obtained by the phase inversion temperature method. Cladosporium sp., Fusarium sp., and Penicillium sp. genera were isolated from cheese samples and used to evaluate antifungal activity. Minimal inhibitory concentrations of non-encapsulated and encapsulated oregano essential oil were determined, and they were influenced by the encapsulation of the essential oil depending on the type of fungus. The antifungal activity of the nanoencapsulated oregano essential oil in cheese slices showed no evidence of an effect of the MICs,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hard cheese; Antifungal activity; Oregano essential oil; Nanodispersions.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000400929
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Antifungal activity of Piper diospyrifolium Kunth (Piperaceae) essential oil BJM
Vieira,Silvia Cristina Heredia; Paulo,Luis Fernando de; Svidzinski,Terezinha Inez Estivaleti; Dias Filho,Benedito Prado; Nakamura,Celso Vataru; Souza,Amanda de; Young,Maria Cláudia Marx; Cortez,Diógenes Aparício Garcia.
In vitro activity of the essential oil from Piper diospyrifolium leaves was tested using disk diffusion techniques. The antifungal assay showed significant potencial antifungal activity: the oil was effective against several clinical fungal strains. The majority compounds in the essential oil were identified as sesquiterpenoids by GC-MS and GC-FID techniques.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Piper diospyrifolium; Essential oil; Antifungal activity.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000300020
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Antifungal activity of some Sternbergia taxa: effects on germ tube and biofilm formation BJPS
Kaskatepe,Banu; Yilmaz,Betul Sever; Acikara,Ozlem Bahadir; Iscan,Gulcin Saltan; Vlainic,Josipa; Kosalec,Ivan.
Natural products are rapidly becoming the primary sources of novel antimicrobial agents, as resistance to existing antimicrobial agents is increasing. Apart from determining the antimicrobial activity of natural products, it is also important to understand their effects on the virulence factors of microorganisms. This study aimed to determine the antimicrobial activity of Sternbergia species prevalent in Turkey and investigate their role in the inhibition of germination tube and biofilm formation, both of which are known to be important virulence factors of Candida albicans. The antimicrobial activities of the plant extracts were evaluated using bore-plate and broth microdilution method. The extracts’ capacity to inhibit the formation of the germ-tube was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antifungal activity; Biofilm inhibition; Candida albicans; Germ tube formation; Virulence factor; Sternbergia spp.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100546
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Antifungal activity of the essential oil from Calendula officinalis L. (asteraceae) growing in Brazil BJM
Gazim,Zilda Cristiane; Rezende,Claudia Moraes; Fraga,Sandra Regina; Svidzinski,Terezinha Inez Estivaleti; Cortez,Diógenes Aparicio Garcia.
This study tested in vitro activity of the essential oil from flowers of Calendula officinalis using disk-diffusion techniques. The antifungal assay results showed for the first time that the essential oil has good potential antifungal activity: it was effective against all 23 clinical fungi strains tested.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Calendula officinalis; Essential oil; Antifungal activity.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000100015
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Antifungal activity of the ethanolic extracts of Punica granatum L. and evaluation of the morphological and structural modifications of its compounds upon the cells of Candida spp. BJM
Anibal,Paula Cristina; Peixoto,Iza Teixeira Alves; Foglio,Mary Ann; Höfling,José Francisco.
Ethanolic crude extracts prepared from the arils and seeds, pericarp, peels and from the whole fruit of Punica granatum, known as pomegranate, had their antifungal activity tested against Candida spp. The ethanolic crude extracts were analyzed by Mass Spectrometry and yielded many compounds such as punicalagin and galladydilacton. The extracts from the pericarp and peel showed activity against Candida spp., with MICs of 125 µg/mL. The effect of pericarp and peel extracts upon the morphological and structure of C. albicans and C. krusei were examined by scanning and transmission electron microscopy, with the visualization of an irregular membrane and hyphae, formation of vacuoles and thickening of the cell wall. The data obtained revealed potential...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Punica granatum; Punicalagin; Antifungal activity; Candida spp.; Electron microscopy.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300027
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Antifungal activity of the extracts and saponins from Sapindus saponaria L. Anais da ABC (AABC)
Tsuzuki,Joyce K.; Svidzinski,Terezinha I.E.; Shinobu,Cristiane S.; Silva,Luiz F.A.; Rodrigues-Filho,Edson; Cortez,Diógenes A.G.; Ferreira,Izabel C.P..
Extracts from the dried pericarp of Sapindus saponaria L. (Sapindaceae) fruits were investigated for their antifungal activity against clinical isolates of yeasts Candida albicans and C. non-albicans from vaginal secretions of women with Vulvovaginal Candidiasis. Four clinical isolates of C. albicans, a single clinical isolated of each of the species C. parapsilosis, C. glabrata, C. tropicalis, and the strain of C. albicans ATCC 90028 were used. The hydroalcoholic extract was bioactivity-directed against a clinical isolate of C. parapsilosis, and showed strong activity. The n-BuOH extract and one fraction showed strong activity against all isolates tested. Further column-chromatography on silica gel separation of this fraction afforded two pure triterpene...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sapindaceae; Sapindus saponaria; Saponins; Antifungal activity; Candida.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000400002
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Antifungal activity of the lemongrass oil and citral against Candida spp. BJID
Silva,Cristiane de Bona da; Guterres,Sílvia S.; Weisheimer,Vanessa; Schapoval,Elfrides E.S..
Superficial mycoses of the skin are among the most common dermatological infections, and causative organisms include dermatophytic, yeasts, and non-dermatophytic filamentous fungi. The treatment is limited, for many reasons, and new drugs are necessary. Numerous essential oils have been tested for both in vitro and in vivo antifungal activity and some pose much potential as antifungal agents. By using disk diffusion assay, we evaluated the antifungal activity of lemongrass oil and citral against yeasts of Candida species (Candida albicans, C. glabrata, C. krusei, C. parapsilosis and C. tropicalis). This study showed that lemongrass oil and citral have a potent in vitro activity against Candida spp.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lemongrass oil; Citral; Antifungal activity; Candida spp.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100014
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ANTIFUNGAL POTENTIAL OF A BRASSICACEOUS WEED Sisymbrium irio AGAINST Macrophomina phaseolina Planta Daninha
JAVAID,A.; AFZAL,L.; SHOAIB,A..
ABSTRACT Macrophomina phaseolina, a soil-borne plant pathogen, has the ability to cause diseases in about 500 plant species. Unfortunately, so far no registered fungicide is available against this fungal pathogen. In the present study, different extracts of Sisymbrium irio, a weed of family Brassicaceae, were tested for evaluation of their antifungal activity against M. phaseolina. In screening bioassays, antifungal activity of methanolic extracts of 1% to 6% concentrations of different parts (leaf, stem, root and fruit) of the weed was assessed against the fungal pathogen. Methanolic leaf and root extracts significantly reduced fungal biomass up to 59% and 69% over control, respectively. Methanolic leaf and root extracts were further partitioned using...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antifungal activity; London rocket; Plant extracts.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582017000100255
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Antifungal properties of Brazilian cerrado plants BJM
Souza,Lúcia Kioko Hasimoto e; Oliveira,Cecília Maria Alves de; Ferri,Pedro Henrique; Santos,Suzana Costa; Oliveira Júnior,Juldásio Galdino de; Miranda,André Thiago Borges; Lião,Luciano Morais; Silva,Maria do Rosário Rodrigues.
Ethanolic extracts from leaves of Hyptis ovalifolia, H. suaveolens, H. saxatilis, Hyptidendrum canum, Eugenia uniflora, E. dysenterica, Caryocar brasiliensis and Lafoensia pacari were investigated for their antifungal activity against dermatophytes. The most effective plants were H. ovalifolia and E. uniflora, while Trichophyton rubrum was the most sensitive among the four dermatophytes species evaluated. This study has demonstrated antifungal properties of Brazilian Cerrado plant extracts in "in vitro" assays.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dermatophytes; Antifungal activity; Plant extracts; Susceptibility tests.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822002000300012
Registros recuperados: 51
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