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Registros recuperados: 21
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Actividad antimicrobiana e irritabilidad vaginal y dérmica de extractos acuosos de hojas secas de Solanum americanum Mill. Plantas Medicinales
Martínez Guerra,María Julia; López Barreiro,Marisol; Morejón Rodríguez,Zulema; Boucourt Rodríguez,Elisa; García Hernández,Ana Ibis.
INTRODUCCIÓN: Solanum americanum Mill. (yerba mora) es usada de forma tradicional para el tratamiento de las úlceras en la piel, se utiliza además como antiinflamatorio y antiséptico en enfermedades de la piel y en cérvico-vaginitis. Sin embargo, existen pocos estudios preclínicos que validen su uso. OBJETIVO: evaluar la actividad antimicrobiana, la irritabilidad vaginal y dérmica de 2 decocciones de hojas secas de Solanum americanum Mill. MÉTODOS: se prepararon 2 extractos acuosos de: a) hojas secas al 20 % y se evaluó la actividad antimicrobiana mediante el método de difusión en agar, frente a los microorganismos Candida albicans, Escherichia coli, Klebsiella pneumoniae y Salmonella thyphymurium; así como la irritabilidad en vagina de coneja por el...
Tipo: Journal article Palavras-chave: Solanum americanum; Antimicrobiana; Irritabilidad dérmica; Irritabilidad vaginal; Solanum americanum; Antimicrobial; Skin irritability; Vaginal irritability.
Ano: 2009 URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962009000100003
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Antibacterial activity of the Antarctic bacterium Janthinobacterium sp: SMN 33.6 against multi-resistant Gram-negative bacteria Electron. J. Biotechnol.
Asencio,Geraldine; Lavin,Paris; Alegría,Karen; Domínguez,Mariana; Bello,Helia; González-Rocha,Gerardo; González-Aravena,Marcelo.
Background The increment of resistant strains to commonly used antibiotics in clinical practices places in evidence the urgent need to search for new compounds with antibacterial activity. The adaptations that Antarctic microorganisms have developed, due to the extreme environment that they inhabit, promote them as a potential new source of active compounds for the control of microorganisms causing infections associated with health care. The aim of this study was to evaluate the antibacterial activity of an ethanol extract of the Antarctic bacterium Janthinobacterium sp., strain SMN 33.6, against nosocomial multi-resistant Gram-negative bacteria. Results Inhibitory activity against human Gram-negative bacterial pathogens, with concentrations that varied...
Tipo: Journal article Palavras-chave: Antarctica; Antimicrobial; Antibiotic resistance; Bacterial pigment.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000100001
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Antimicrobial and molecular interaction studies on derivatives of curcumin against Streptococcus pneumoniae which caused pneumonia Electron. J. Biotechnol.
Li,Liang-Mei; Li,Jun; Zhang,Xiu-Ying.
Background: The antimicrobial properties and molecular interaction analysis of curcumin and its derivatives against three different strains of Streptococcus pneumoniae (Penicillin-susceptible, Penicillin-intermediate and Penicillin-resistant) are studied. Results: These properties were analyzed based on the measurement of the inhibition zone, minimum inhibitory concentration (MIC), and rate of kill revealed that curcumin monoglucoside, curcumin diglucoside and curcumin possessed strong antimicrobial properties even on the Penicillin-resistant strains. Additionally, the molecular docking simulation analyses against Penicillin Binding Protein of S. pneumoniae also confirm that these compounds docked at the active site of the enzyme. Further, the molecular...
Tipo: Journal article Palavras-chave: Antimicrobial; Curcumin; MIC; Molecular docking; Penicillin-resistant.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582016000100002
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Antimicrobial Compounds from Eukaryotic Microalgae against Human Pathogens and Diseases in Aquaculture ArchiMer
Falaise, Charlotte; Francois, Cyrille; Travers, Marie-agnes; Morga, Benjamin; Haure, Joel; Tremblay, Rejean; Turcotte, Francois; Pasetto, Pamela; Gastineau, Romain; Hardivillier, Yann; Leignel, Vincent; Mouget, Jean-luc.
The search for novel compounds of marine origin has increased in the last decades for their application in various areas such as pharmaceutical, human or animal nutrition, cosmetics or bioenergy. In this context of blue technology development, microalgae are of particular interest due to their immense biodiversity and their relatively simple growth needs. In this review, we discuss about the promising use of microalgae and microalgal compounds as sources of natural antibiotics against human pathogens but also about their potential to limit microbial infections in aquaculture. An alternative to conventional antibiotics is needed as the microbial resistance to these drugs is increasing in humans and animals. Furthermore, using natural antibiotics for...
Tipo: Text Palavras-chave: Biological activity; Antimicrobial; Antibacterial; Antifungal; Antiviral; Biological activity; Haslea; Microalgae; Sustainable aquaculture.
Ano: 2016 URL: http://archimer.ifremer.fr/doc/00349/46052/45719.pdf
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Antioxidant, antimicrobial, toxicity and analgesic properties of ethanol extract of Solena amplexicaulis root Biol. Res.
Kabir,Md Golam; Rahman,Md Monsor; Ahmed,Nazim Uddin; Fakruddin,Md; Islam,Saiful; Mazumdar,Reaz Mohammad.
BACKGROUND: This study was subjected to investigate different pharmacological properties of ethanol extract ofSolena amplexicaulis root. RESULTS: The extract contains flavonoid, alkaloid, saponin and steroid compounds. The extract exhibited excellent antioxidant activity in DPPH radical scavenging activity. The extract also showed potent activity in brine shrimp lethality bioassay. The LC50 value was found to 44.677 µg/ml. The extract showed better anti-bacterial activity against gram-negative bacteria. In antifungal assay, the maximum 79.31% of anti-mycotic activity was observed against Aspergillus ochraceus while minimum 44.2% against Rhizopus oryzae. MIC value ranged between 1500 - 3000 µg/ml. The extract was found moderately toxic with a 24-hr LD50...
Tipo: Journal article Palavras-chave: Solena amplexicaulis; Antioxidant; Antimicrobial; Acute toxicity.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100036
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Assessment of natural vegetal extracts in the inhibition of Leuconostoc mesenteroides MSI Agriscientia (Córdoba)
Serra,M. A; Garnero,J. A; Nicolau,V. V; Andreatta,A. E.
The present study focuses on the assessment of natural vegetal extracts in the inhibition of bacteria altering Vienna sausages whose growth becomes evident in the vacuum packed product after two to three weeks of refrigerated storage causing packages to swell. The different natural extracts were obtained by means of steam stripping, microwave assisted extraction and ultrasound assisted extraction. Apart from these extracts, commercial essential oils, pure compounds present in the vegetal kingdom and solutions were also evaluated. For each of the extracts, microbial sensitivity tests were carried out in order to assess the inhibitory/bactericidal effect against Leuconostoc mesenteroides MS1. It has been found that the essential oils obtained from Citrus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Leuconostoc mesenteroides MS1; Antimicrobial; Essential oil; Inhibitor; Bactericide; Vienna sausage.
Ano: 2018 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-298X2018000100006
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Atividade antimicrobiana do óleo essencial de capim-limão contra Salmonella Typhimurium em repolho. Infoteca-e
MACHADO, T. F.; PEREIRA, R. de C. A.; REBOUÇAS, J. de O.; PONTES, C. M.; XAVIER, T. F..
2013
Tipo: Boletim de Pesquisa e Desenvolvimento (INFOTECA-E) Palavras-chave: Cymbopogon citratus; Óleo essencial; Antimicrobiano; Sanitização; Cymbopogon citratus; Essential oil; Antimicrobial.
Ano: 2013 URL: http://www.infoteca.cnptia.embrapa.br/handle/doc/981606
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Atividade in vitro do extrato de própolis contra agentes bacterianos da mastite bovina. Repositório Alice
LOGUERCIO, A.P.; GROFF, A.C.M.; PEDROZZO, A.F.; WITT, N.M.; SILVA, M.S. e; VARGAS, A.C. de.
Este trabalho foi desenvolvido com o objetivo de avaliar a atividade in vitro do extrato alcoólico de própolis, contra agentes da mastite bovina, comparando-o aos principais antimicrobianos utilizados no tratamento convencional. Foram utilizados 36 isolados coagulase-positivos de Staphylococcus sp. e 27 isolados de Streptococcus sp.; 94,4% dos Staphylococcus sp. e 85,2% dos Streptococcus sp. foram susceptíveis ao extrato de própolis.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Staphylococcus; Streptococcus; Susceptibilidade; Antimicrobianos; Susceptibility; Antimicrobial.
Ano: 2006 URL: http://www.alice.cnptia.embrapa.br/handle/doc/118458
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Avaliação do revestimento de quitosana como carreador de nisina para prolongar a vida de prateleira de queijos caprinos. Repositório Alice
SOUSA, C. R. V.; BASTOS, M. do S. R.; BORGES, M. de F.; OLIVEIRA, M. de A.; MENDES, F. R. S.; ROSENTHAL, A.; BENEVIDES, S. D..
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Polymer; Biodegradable; Antimicrobial; Dairy goat products; Polímero; Biodegradável; Antimicrobiano; Lácteos caprinos.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1059214
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Clavanin bacterial sepsis control using a novel methacrylate nanocarrier. Repositório Alice
SAÚDE, A. C. M.; OMBREDANE, A. S.; SILVA, O. N.; BARBOSA, J. A. R. G.; MORENO, S. E.; ARAUJO, A. C. G.; FALCAO, R.; SILVA, L. P.; DIAS, S. C.; FRANCO, O. L..
2014
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Antimicrobial; Nanoparticles; Nanobiotechnology; Peptide.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1005987
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Differential distribution and defence involvement of antimicrobial peptides in mussel ArchiMer
Mitta, Guillaume; Vandenbulcke, Franck; Noel, Thierry; Romestand, Bernard; Beauvillain, Jean Claude; Salzet, Michel; Roch, Philippe.
In previous papers, we characterised 3 types of 4-kDa, cysteine-rich, cationic antimicrobial peptides: MGDs (for Mytilus galloprovincialis defensins), mytilins and myticins, which are abundant in the mussel hemocytes. In the present work, me revealed a differential distribution of the cells expressing the different genes. In addition, using confocal and electron microscopy, we confirmed that defensins and mytilins were partially located in different sub-types of circulating hemocytes although the peptides can be located in the same cell, and even in the same granule. We also demonstrated that mytilins exert their microbicidal effect within the cells through the process of phagosome-mytilin granule fusion leading to the co-location of ingested bacteria and...
Tipo: Text Palavras-chave: Innate immunity; Hemocyte; Mussel; Myticin; Mytilin; Defensin; Antimicrobial.
Ano: 2000 URL: http://archimer.ifremer.fr/doc/2000/publication-413.pdf
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Essential oil from Chenopodium ambrosioides L.: secretory structures, antibacterial and antioxidant activities Biological Sciences
Santiago, Juliana Andrade; Cardoso, Maria das Graças; Batista, Luís Roberto; Castro, Evaristo Mauro de; Teixeira, Maria Luisa; Pires, Marinês Ferreira.
The aim of this study was to evaluate the antibacterial and antioxidant activities of essential oil from Chenopodium ambrosioides L. and to determine its secretory structures. The essential oil was extracted through the hydrodistillation technique using a modified Clevenger apparatus (2 hours) and chemically characterized by GC/MS and GC-FID. The antioxidant activity was determined by monitoring the reduction of 2,2-diphenyl-1-picrylhydrazyl (DPPH) and by the oxidation of the β-carotene/linoleic acid system. The evaluation of antibacterial activity was performed by the agar cavity diffusion technique using the microorganisms Staphylococcus aureus, Listeria monocytogenes, Escherichia coli and Salmonella Cholerasuis. The characterization of trichomes was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Natural products; Antioxidant assays; Antimicrobial; Trichomes.
Ano: 2016 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/28303
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Estimation of antioxidant, antimicrobial activity and brine shrimp toxicity of plants collected from Oymyakon region of the Republic of Sakha (Yakutia), Russia Biol. Res.
Paudel,Babita; Bhattarai,Hari Datta; Chan Kim,Il; Lee,Hyoungseok; Sofronov,Roman; Ivanova,Lena; Poryadina,Lena; Yim,Joung Han.
BACKGROUND: Several plants are reported to be produced various biological active compounds. Lichens from the extreme environments such as high altitude, high UV, drought and cold are believed to be synthesized unique types of secondary metabolites than the other one. Several human pathogenic bacteria and fungi have been muted into drug resistant strains. Various synthetic antioxidant compounds have posed carcinogenic effects. This phenomenon needs further research for new effective drugs of natural origin. This manuscript aimed to screen new source of biological active compounds from plants of subarctic origin. RESULTS: A total of 114 plant species, including 80 species of higher plants, 19 species of lichens and 15 species of mosses, were collected from...
Tipo: Journal article Palavras-chave: Antimicrobial; Antioxidant; Brine shrimp; DPPH; Lichen; Moss.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100010
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Evidence of a bactericidal permeability increasing protein in an invertebrate, the Crassostrea gigas Cg-BPI ArchiMer
Gonzalez, Marcelo; Gueguen, Yannick; Destoumieux Garzon, Delphine; Romestand, Bernard; Fievet, Julie; Pugniere, M; Roquet, F; Escoubas, Jean-michel; Vandenbulcke, F; Levy, O; Saune, Laure; Bulet, P; Bachere, Evelyne.
A cDNA sequence with homologies to members of the LPS-binding protein and bactericidal/permeability-increasing protein (BPI) family was identified in the oyster Crassostrea gigas. The recombinant protein was found to bind LIPS, to display bactericidal activity against Escherichia coli, and to increase the permeability of the bacterial cytoplasmic membrane. This indicated that it is a BPI rather than an LPS-binding protein. By in situ hybridization, the expression of the C gigas BPI (Cg-bpi) was found to be induced in hemocytes after oyster bacterial challenge and to be constitutive in various epithelia of unchallenged oysters. Thus, Cg-bpi transcripts were detected in the epithelial cells of tissues/organs in contact with the external environment (mantle,...
Tipo: Text Palavras-chave: Oyster innate immunity; Mollusk; Hemocyte; Epithelia; Antimicrobial.
Ano: 2007 URL: http://archimer.ifremer.fr/doc/2007/publication-3564.pdf
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Intein-mediated expression of cecropin in Escherichia coli Electron. J. Biotechnol.
Díaz,Mauricio; Venturini,Elena; Marchetti,Stefano; Arenas,Gloria; Marshall,Sergio H.
Different strategies have been used to overcome the difficulties to produce antimicrobial peptides. Here we used Intein Mediated Purification with an Affinity Chitin-binding Tag (IMPACT-System, New England Biolabs) for the expression of the antimicrobial peptide cecropin to reduce its sensitivity to intracellular proteases and use its inducible self-cleaving capability to remove the carrier. Cecropin was cloned into suitable expression vector pTYB11, and expression induced by IPTG in Escherichia coli ER2566. The use of 22ºC induction allowed the expression of cecropin with its intein carrier in soluble form. Cell extracts were purified by chitin affinity chromatography and intein-mediated splicing of the target protein was achieved by thiol addition,...
Tipo: Journal article Palavras-chave: Antimicrobial; Cecropin; Fusion; Intein; Peptide; Soluble.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582012000200003
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Psidium cattleianum fruits: A review on its composition and bioactivity. Repositório Alice
PEREIRA, E. dos S.; VINHOLES, J.; FRANZON, R. C.; DALMAZO, G.; VIZZOTTO, M.; NORA, L..
bitstream/item/181667/1/Marcia-Vizzotto-Food-Chemistry-araca-review.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Antidiabetic; Anticancer; Antimicrobial; Anti-inflammatory; Anti-aging; Araçá; Antioxidante; Chemical composition.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1094287
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Recombinant Cry1la protein is highly toxic to cotton boll weevil (Anthonomus grandis boheman) and fall armyworm (Spodoptera frugiperda). Repositório Alice
MARTINS, E. S.; AGUIAR, R. W. D. S.; MARTINS, N. F.; MELATTI, V. M.; FALCÃO, R.; GOMES, A. C. M. M.; RIBEIRO, B. M.; MONNERAT, R. G..
bitstream/item/177852/1/SP-19622-ID-30910.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Antimicrobial; Bacillus; Biocontrol; Genes; Pests.
Ano: 2008 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/190641
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Synthesis of pure stereoisomers of benzo[b]thienyl dehydrophenylalanines by Suzuki cross-coupling. Preliminary studies of antimicrobial activity IPB - Escola Superior Agrária
Abreu, Ana S.; Ferreira, Paula M.T.; Monteiro, Luís S.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Leticia M..
Several benzo[b]thienyldehydrophenylalanines were synthesized from pure stereoisomers of the methyl ester of N-(tertbutoxycarbonyl)- b-bromodehydrophenylalanine as an extension of our previously reported method for the synthesis of dehydrotryptophan analogues to dehydrophenylalanine derivatives. The latter were obtained in high yields by N-deprotection and bromination of N,N-bis-(tertbutoxycarbonyl)-( Z)-dehydrophenylalanine using TFA and NBS. This was carried out in two steps or in a one pot procedure resulting in different E/Z ratios. These compounds were coupled under Suzuki cross-coupling conditions [Pd(PPh3)4, Na2CO3, DME/H2O] with several boronic benzo[b]thienyl acids in good to high yields maintaining the stereochemistry of the starting materials....
Tipo: Article Palavras-chave: Amino acids; Dehydrophenylalanines; Benzo[b]thiophenes; Suzuki coupling; Palladium; Antimicrobial.
Ano: 2004 URL: http://hdl.handle.net/10198/822
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Teste de susceptibilidade a antimicrobianos de isolados de Escherichia coli provenientes de queijos a base de leite não pasteurizado. Repositório Alice
RIBEIRO, L. R; BARBOSA, M. M. C.; PINTO, F. R.; SOUZA, V. de; OLIVEIRA, M. C.; BORGES, L. A.; MEDEIROS, M. I. M.; AMARAL, L. A.; FAIRBROTHER, J. M..
2013
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Antimicrobiano; Susceptibilidade; Resistência antimicrobiana; Escherichia coli; Bactéria patogênica; Queijo; Produto derivado do leite; Pasteurização; Patogenicidade; Segurança alimentar; Food security; Milk; Antimicrobial; Chesse; Pathogenicity; Resistance to antibiotics; Pathogenic bacteria; Pasteurization; Milk byproducts.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/969531
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Toxic, antimicrobial and hemagglutinating activities of the purple fluid of the sea hare Aplysia dactylomela Rang, 1828 BJMBR
Melo,V.M.M.; Fonseca,A.M.; Vasconcelos,I.M.; Carvalho,A.F.F.U..
The antimicrobial, hemagglutinating and toxic activities of the purple fluid of the sea hare Aplysia dactylomela are described. Intact or dialyzed purple fluid inhibited the growth of species of Gram-positive and Gram-negative bacteria and the action was not bactericidal but bacteriostatic. The active factor or factors were heat labile and sensitive to extreme pH values. The fluid preferentially agglutinated rabbit erythrocytes and, to a lesser extent, human blood cells, and this activity was inhibited by the glycoprotein fetuin, a fact suggesting the presence of a lectin. The fluid was also toxic to brine shrimp nauplii (LD50 141.25 µg protein/ml) and to mice injected intraperitoneally (LD50 201.8 ± 8.6 mg protein/kg), in a dose-dependent fashion. These...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aplysia; Antimicrobial; Purple fluid; Toxicity; Hemagglutinating activity.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000600010
Registros recuperados: 21
Primeira ... 12 ... Última
 

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