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Registros recuperados: 7
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A direct contact between astrocyte and vitreous body is possible in the rabbit eye due to discontinuities in the basement membrane of the retinal inner limiting membrane BJMBR
Haddad,A.; Salazar,J.J.; Laicine,E.M.; Ramírez,A.I.; Ramírez,J.M.; Triviño,A..
Different from most mammalian species, the optic nerve of the rabbit eye is initially formed inside the retina where myelination of the axons of the ganglion cells starts and vascularization occurs. Astrocytes are confined to these regions. The aforementioned nerve fibers known as medullated nerve fibers form two bundles that may be identified with the naked eye. The blood vessels run on the inner surface of these nerve fiber bundles (epivascularization) and, accordingly, the accompanying astrocytes lie mostly facing the vitreous body from which they are separated only by the inner limiting membrane of the retina. The arrangement of the astrocytes around blood vessels leads to the formation of structures known as glial tufts. Fragments (N = 3) or whole...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Astrocyte; Basement membrane; Inner limiting membrane; Vitreous body; Rabbit retina; Plasma membrane.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000200007
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Alteration of Dentate Gyrus Astrocytes in Diabetic Rats: Protective Role of Urtica dioica International Journal of Morphology
Golalipour,Mohammad Jafar; Ghafari,Soraya; Latifimoghadam,Mohammad Hossein; Kaboli,Sakineh.
Diabetes mellitus can cause astrocytes alterations in the central nervous system. Urtica dioica (Nettle) is among several species listed for their use against diabetes in folk medicine. Therefore, this study was done to evaluate the protective effect of Urtica dioica on astrocytes density of the dentate gyrus in STZ induced diabetic rats. In this experimental study, 21 male albino Wistar rats were randomly allocated equally into normal, diabetic and protective (nettle treated diabetic) groups. Hyperglycemia was induced by streptozotocin (80 mg/kg) in the animals of diabetic and treatment groups. Before induction of diabetes in animals, animals in protective group received hydroalcoholic extract of Urtica dioica (100 mg/kg/BW /day) for five days...
Tipo: Journal article Palavras-chave: Diabetes; Astrocyte; Urtica dioica; Dentate gyrus.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400039
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Analysis of trophic responses in lesioned brain: focus on basic fibroblast growth factor mechanisms BJMBR
Chadi,G.; Fuxe,K..
The actions of fibroblast growth factors (FGFs), particularly the basic form (bFGF), have been described in a large number of cells and include mitogenicity, angiogenicity and wound repair. The present review discusses the presence of the bFGF protein and messenger RNA as well as the presence of the FGF receptor messenger RNA in the rodent brain by means of semiquantitative radioactive in situ hybridization in combination with immunohistochemistry. Chemical and mechanical injuries to the brain trigger a reduction in neurotransmitter synthesis and neuronal death which are accompanied by astroglial reaction. The altered synthesis of bFGF following brain lesions or stimulation was analyzed. Lesions of the central nervous system trigger bFGF gene expression by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Radioautography; In situ hybridization; Basic fibroblast growth factor; FGF receptor; Astrocyte; Image analysis; Central nervous system; Brain lesion.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000200007
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Cross-talk between neurons and glia: highlights on soluble factors BJMBR
Gomes,F.C.A.; Spohr,T.C.L.S.; Martinez,R.; Moura Neto,V..
The development of the nervous system is guided by a balanced action between intrinsic factors represented by the genetic program and epigenetic factors characterized by cell-cell interactions which neural cells might perform throughout nervous system morphogenesis. Highly relevant among them are neuron-glia interactions. Several soluble factors secreted by either glial or neuronal cells have been implicated in the mutual influence these cells exert on each other. In this review, we will focus our attention on recent advances in the understanding of the role of glial and neuronal trophic factors in nervous system development. We will argue that the functional architecture of the brain depends on an intimate neuron-glia partnership.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Neuron-glia interaction; Trophic factors; Astrocyte; Neuron; Nervous system.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000500008
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Effect of Scopolamine-based Amnesia on the Number of Astrocytes in the Rat's Hippocampus International Journal of Morphology
Jahanshahi,M; Azami,N. S; Nickmahzar,E.
As neuron­astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms. In this study, the effect of scopolamine based amnesia on the number of astrocytes in rats' hippocampus was studied. Adult male albino Wistar rats were bilaterally cannulated into the CA1 region and animals received saline or different doses of scopolamine (0.5, 1 and 2 mg/ rat, intra - CA1), immediately after training. Then all the rats were sacrificed and coronal sections were taken from the dorsal hippocampal formation of the right cerebral hemispheres and stained with PTAH. The area densities of the astrocytes in dentate gyrus were measured and compared in the all groups (p < 0.05). Data...
Tipo: Journal article Palavras-chave: Scopolamine; Amnesia; Astrocyte; Hippocampus; Rat.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200004
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Glial fibrillary acidic protein (GFAP): modulation by growth factors and its implication in astrocyte differentiation BJMBR
Gomes,F.C.A.; Paulin,D.; Moura Neto,V..
Intermediate filament (IF) proteins constitute an extremely large multigene family of developmentally and tissue-regulated cytoskeleton proteins abundant in most vertebrate cell types. Astrocyte precursors of the CNS usually express vimentin as the major IF. Astrocyte maturation is followed by a switch between vimentin and glial fibrillary acidic protein (GFAP) expression, with the latter being recognized as an astrocyte maturation marker. Levels of GFAP are regulated under developmental and pathological conditions. Upregulation of GFAP expression is one of the main characteristics of the astrocytic reaction commonly observed after CNS lesion. In this way, studies on GFAP regulation have been shown to be useful to understand not only brain physiology but...
Tipo: Info:eu-repo/semantics/article Palavras-chave: CNS; Astrocyte; Growth factors; Intermediate filaments; GFAP; Vimentin; GFAP gene.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500016
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The Preventive and Treatment Effect of Urtica dioica on Astrocyte Density in the CA1 and CA3 Subfields of Hippocampus in STZ Induced Diabetic Rats International Journal of Morphology
Golalipour,Mohammad Jafar; Jahanshahi,Mehrdad; Ghafari,Soraya; Afshar,Mohammad.
Several animal model studies have shown that Diabetes mellitus can affect on the activity of hippocampus astrocytes, but these studies reported controversial findings. This study was done to evaluate the preventive and treatment effect of Urtica dioica (U. dioica) on astrocytes density in the CA1 and CA3 subfields of hippocampus of streptozotocin (STZ) induced diabetic rats. Twenty-eight male albino Wistar rats were randomly allocated equally into control, diabetic, U. dioica treatment and U. dioica preventive groups. Hyperglycemia was induced by STZ (80 mg/kg/BW). One week after injection of the streptozotocin, animals in treatment group were received hydroalcoholic extract of U. dioica (100 mg/kg/BW /day) for 4 weeks by intraperitoneally. In preventive...
Tipo: Journal article Palavras-chave: Diabetes; Astrocyte; Urtica dioica; Hippocampus; CA1; CA3; Rat.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200057
Registros recuperados: 7
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