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Antagonic effect of the inhibition of inducible nitric oxide on the mortality of mice acutely infected with Escherichia coli and Bacteroides fragilis BJMBR
Astolfi,R.S.; Khouri,D.G.; Brandizzi,L.I.V.; Ávila-Campos,M.J.; Andrade Jr.,H.F. de.
Sepsis, the leading cause of death in intensive care units, is associated with overproduction of nitric oxide (NO) due to inducible NO synthase (iNOS), responsible for some of the pathologic changes. Aminoguanidine (AG) is a selective iNOS inhibitor with reported inconsistent actions in sepsis. To investigate the influence of iNOS, we studied models of acute bacterial sepsis using acute challenges with aerobic (Escherichia coli) and anaerobic (Bacteroides fragilis) bacteria in the presence of AG. Six-week-old, 23 g, male and female BALB/c and C57Bl/6j mice, in equal proportions, were inoculated (ip) with bacteria in groups of 4 animals for each dose and each experiment in the absence or presence of AG (50 mg/kg, ip, starting 24 h before challenge and daily...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Nitric oxide; Sepsis; Experimental model; Bacterial infections; Escherichia coli; Bacteroides fragilis.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000300006
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Bacteroides fragilis endocarditis: a case report and review of literature BJID
Rodrigues,Cristhieni; Siciliano,Rinaldo Focaccia; Zeigler,Rogerio; Strabelli,Tania Mara Varejão.
Endocarditis due to Bacteroides fragilis is a rare disorder. This article describes a case of Bacteroides fragilis endocarditis associated with portal and superior mesenteric venous thrombosis in a patient without preexisting valvular heart disease and review the cases of endocarditis due to this anaerobic bacterium in medical literature since 1980.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Endocarditis; Bacteroides fragilis; Gram-negative anaerobic bacteria.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100020
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Clinical aspects of experimental peritonitis in horses Ciência Rural
Mendes,Luiz Cláudio Nogueira; Marques,Luiz Carlos; Iturrino,Ruben Pablo Schocken; Ávila,Fernando Antônio de.
Sixteen adult horses were randomly divided into 4 equal groups (GI, GII, GIII and GIV) of 4 animals and each group was injected intraperitoneally with one of the following suspension: GI (100 x 10(7) colony-forming units (CFU) of Escherichia coli diluted in 500ml of 0.9% saline); GII (100 x 10(7) CFU of Bacteroides fragilis in 500ml of 0.9% saline); GIII (100 x 10(7) CFU of E. coli in combination with 100 x 10(7) CFU of B. fragilis in 500ml of 0.9% saline); GIV (500ml of 0.9% saline). Abdominal wall sensitivity to external pressure and tension, diarrhea, decreased intestinal sounds and increased of heart rate were the clinical signs more frequently observed in inoculated horses. Horses inoculated with pure cultures of either E. coli or B. fragilis...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Peritonitis; Horses; Escherichia coli; Bacteroides fragilis.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84781999000300019
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Enterotoxigenic and non-enterotoxigenic Bacteroides fragilis from fecal microbiota of children BJM
Ignacio,Aline; Fernandes,Miriam Rodriguez; Avila-Campos,Mario Julio; Nakano,Viviane.
Enterotoxigenic Bacteroides fragilis (ETBF) is an important part of the human and animal intestinal microbiota and is commonly associated with diarrhea. ETBF strains produce an enterotoxin encoded by the bft gene located in the B. fragilis pathogenicity island (BfPAI). Non-enterotoxigenic B. fragilis (NTBF) strains lack the BfPAI and usually show two different genetic patterns, II and III, based on the absence or presence of a BfPAI-flanking region, respectively. The incidence of ETBF and NTBF strains in fecal samples isolated from children without acute diarrhea or any other intestinal disorders was determined. All 84 fecal samples evaluated were B. fragilis-positive by PCR, four of them harbored the bft gene, 27 contained the NTBF pattern III DNA...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteroides fragilis; Children; ETBF; NTBF.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401141
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Experimental peritonitis in horses. Hematological and biochemistry aspects Braz. J. Vet. Res. Anim. Sci.
MENDES,Luiz Cláudio Nogueira; MARQUES,Luiz Carlos; SCHOCKEN-ITURRINO,Ruben Pablo; ÁVILA,Fernando Antônio de; MALHEIROS,Euclides Braga.
Sixteen adult horses were randomly divided into 4 equal groups (GI, GII, GIII and GIV) of 4 animals and each group was injected intraperitoneally with one of the following suspension: Group I, 100 x 10(7) colony-forming units (CFU) of E. coli diluted in 500 ml of 0.9% saline; Group II, 100 x 10(7) CFU of Bacteroides fragilis in 500 ml of 0.9% saline; Group III, 100 x 10(7) CFU of E. coli in combination with 100 x 10(7) CFU of B. fragilis in 500 ml of 0.9% saline; Group IV, 500 ml of 0.9% saline. Leukopenia appeared in all animals inoculated with bacteria within the first six hours of the experiment. After this period, leukocytosis was observed in some inoculated horses. Horses inoculated with pure cultures of either E. coli or B. fragilis demonstrated mild...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Peritonitis; Horses; Escherichia coli; Bacteroides fragilis.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962000000200011
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Experimental peritonitis in horses: peritoneal fluid composition Arq. Bras. Med. Vet. Zootec.
Mendes,L.C.N.; Marques,L.C.; Bechara,G.H.; Peiró,J.R..
Sixteen adult horses were randomly divided into four equal groups of four animals and each group was injected intraperitoneally with one of the following suspension: Group I, 100×10(7) colony-forming units (CFU) of E. coli diluted in 500ml of 0.9% saline; Group II, 100×10(7) CFU of Bacteroides fragilis in 500ml of 0.9% saline; Group III, 100×10(7) CFU of E. coli in combination with 100×10(7) CFU of B. fragilis in 500ml of 0.9% saline; Group IV, 500ml of 0.9% saline. A significant increase in leukocyte number was observed in the peritoneal fluid by four hours after the inoculations in animals of Group I and II, and by eight hours in animals of Group III. The highest cell count observed was 516×10³ leukocytes/mm³. Significant increases in peritoneal fluid...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Horses; Peritonitis; Escherichia coli; Bacteroides fragilis.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09351999000300003
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Inactivation of MarR gene homologs increases susceptibility to antimicrobials in Bacteroides fragilis BJM
Silva,Clara Maria Guimarães; Silva,Déborah Nascimento dos Santos; Costa,Scarlathe Bezerra da; Almeida,Juliana Soares de Sá; Boente,Renata Ferreira; Teixeira,Felipe Lopes; Domingues,Regina Maria Cavalcanti Pilotto; Lobo,Leandro Araujo.
ABSTRACT Bacteroides fragilis is the strict anaerobic bacteria most commonly found in human infections, and has a high mortality rate. Among other virulence factors, the remarkable ability to acquire resistance to a variety of antimicrobial agents and to tolerate nanomolar concentrations of oxygen explains in part their success in causing infection and colonizing the mucosa. Much attention has been given to genes related to multiple drug resistance derived from plasmids, integrons or transposon, but such genes are also detected in chromosomal systems, like the mar (multiple antibiotic resistance) locus, that confer resistance to a range of drugs. Regulators like MarR, that control expression of the locus mar, also regulate resistance to organic solvents,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteroides fragilis; Anaerobic bacteria; Multi-drug resistance; Oxidative stress resistance.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000100200
Registros recuperados: 7
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