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Expression of MuRF1 and MAFbx in Donor and Recipient Muscles after Musculocutaneous Nerve Transection and Partial Pectoralis Major Muscle Transfer for Reconstruction of Elbow Flexion in Rats International Journal of Morphology
Yang,Shengbo; Yue,Ning; Zeng,Xueqing.
The expression of MuRF1 and MAFbx in a denervated muscle has previously been studied. However, the expression of MuRF1 and MAFbx in the recipient and donor muscles after muscle transfer for reconstruction of joint function has not been sufficiently investigated. Forty-two adult Sprague-Dawley rats were divided into 7 groups: normal, 1 w post-, 2 w post-, and 4 w post-musculocutaneous nerve transection; and 1 w post-, 2 w post-, and 4 w post-reconstruction of elbow flexion. Muscle wet weights were assessed, and MuRF1 and MAFbx mRNA expressions were detected by polymerase chain reaction. The length of the oblique part of the pectoralis major of an SD rat is sufficient for suture to the insertion of the biceps brachii tendon. The muscle wet weight and the wet...
Tipo: Journal article Palavras-chave: Musculocutaneous nerve injury; MuRF1; MAFbx; Pectoralis major; Biceps Brachii.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300027
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