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A Novel Porous Diamond - Titanium Biomaterial: Structure, Microstructure, Physico-Mechanical Properties and Biocompatibility Anais da ABC (AABC)
GUIMARÃES,ZULMIRA A.S.; DAMATTA,RENATO A.; GUIMARÃES,RENAN S.; FILGUEIRA,MARCELLO.
ABSTRACT With the aim of introducing permanent prostheses with main properties equivalent to cortical human bone, Ti-diamond composites were processed through powder metallurgy. Grade 1 titanium and mixtures of Ti powder with 2%, 5% and 10 wt% diamond were compacted at 100MPa, and then sintered at 1250°C/2hr/10-6mbar. Sintered samples were studied in the point of view of their microstructures, structures, yield strength and elastic modulus. The results showed that the best addition of diamonds was 2 wt%, which led to a uniform porosity, yield strength of 370MPa and elastic modulus of 13.9 GPa. Samples of Ti and Ti-2% diamond were subjected to in vitro cytotoxicity test, using cultures of VERO cells, and it resulted in a biocompatible and nontoxic composite...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biomaterials; Titanium; Diamond; Sintering; Characterization; Biocompatibility..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000603111
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Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study International Journal of Morphology
Issa,Joao Paulo Mardegan; Petenusci,Sergio Olavo; Siéssere,Selma; Regalo,Simone Cecilio Hallak; Lopes,Ruberval Armando; Di Matteo,Miguel Ángel Sala; Iyomasa,Mamie Mizusaki; Defino,Helton Luiz Aparecido.
The aim of this study was to evaluate the calcium dosage of the newly formed bone, in critical bone defects created on the calvarial tissue and filled by different substances, in male Wistar rats. A cylindrical critical bone defect (6x2mm) was created in the posterior portion, left side, on the calvarial bone in nine animals and filled with: animals' coagulum, monoolein gel, poloxamer gel, monoolein gel + 1µg rhBMP-2, monoolein gel + 3µg rhBMP-2, monoolein gel + 7µg rhBMP-2, poloxamer gel + 1µg rhBMP-2, poloxamer gel + 3µg rhBMP-2, poloxamer gel + 7µg rhBMP-2. The results of this study showed a positive correlation between the calcium dosage analysis and the newly formed bone
Tipo: Journal article Palavras-chave: Bone repair; Biomaterials; RhBMP-2; Carriers; Calcium.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300006
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Biocompatibility, osteointegration, osteoconduction, and biodegradation of a hydroxyapatite-polyhydroxybutyrate composite BABT
Reis,Emily Correna Carlo; Borges,Andréa Pacheco Batista; Fonseca,Cláudio César; Martinez,Mastoby Miguel Martinez; Eleotério,Renato Barros; Morato,Gláucia Oliveira; Oliveira,Paulo Miranda.
In this work, biocompatibility, osteointegration, osteoconductivity, and biodegradation of a hydroxyapatite polyhydroxybutyrate new composite were evaluated. The composite was implanted in rabbits' bone defects and clinical, radiographic, histological, and histomorphometric data of these animals were compared with those of unfilled defects on the days 8th, 45th, and 90th after surgery. No significant differences existed between the groups for the evaluated clinical parameters. Radiographs showed bone-composite direct contact. Bone formed within the defect, interface and inside the composite. Significant differences were found between the bone and connective tissues percentage within the defect at all dates and at the interface on the 45th day, bone tissue...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biomaterials; Bone; Biocompatibility; Biodegradation; Hydroxyapatite-polyhydroxybutyrate composite.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000400010
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Biomaterials Applied to the Bone Healing Process International Journal of Morphology
Nascimento,Cássio do; Issa,João Paulo Mardegan; Oliveira,Rafael Ramos de; Iyomasa,Mamie Mizusaki; Siéssere,Selma; Regalo,Simone Cecilio Hallak.
An recent innovation in medicine is the application of the biomaterials in bone healing process. Thus, this work has the objective to present an overview of the uses and insertions of these biomaterials and its components mostly used in the bone repair
Tipo: Journal article Palavras-chave: Bone repair; Biomaterials; Cicatricial process.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400025
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BIOREFINERIES USING AGRICULTURAL RESIDUE FEEDSTOCK IN THE GREAT PLAINS AgEcon
Leistritz, F. Larry; Hodur, Nancy M.; Senechal, Donald M.; Stowers, Mark D.; McCalla, Darold; Saffron, Chris M..
Rising prices and uncertain supplies of petroleum, together with environmental concerns regarding fossil fuel combustion, has enhanced interest in biobased products and fuels. The work reported here analyzes the feasibility of a multi-product biorefinery using wheat straw as feedstock that produces ethanol, electricity, and cellulose nanofibers. The nanofibers (nanowhiskers) would be used as reinforcements in a biobased nanocomposite material that could substitute for fiberglass in many applications. The analysis indicates that, at 2005 prices and costs, the biorefinery would be marginally profitable. Anticipated advances in bioprocessing technology would enhance profitability. The facility would also make a substantial contribution to the biorefinery site...
Tipo: Working or Discussion Paper Palavras-chave: Biomass; Biomaterials; Ethanol; Wheat straw; Cellulose nanowhiskers (CNW); Economic development; Resource /Energy Economics and Policy.
Ano: 2007 URL: http://purl.umn.edu/7323
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Bone Augmentation With Occlusive Barriers and Cortical Particulate Allograft in Transverse Maxillary Defects: A Pilot Study International Journal of Morphology
Beltrán,Víctor; Engelke,Wilfried; Fuentes,Ramón; Decco,Oscar; Prieto,Ruth; Wilckens,Mario; Borie,Eduardo.
The centripetal resorption of maxilla is a continuous process after tooth loss. For treatment of deficient bone sites, autologous bone grafts may be used, as an alternative, biomaterials can be applied which do not require intra or extraoral donor sites. The present report describes the use of occlusive barriers and cortical particulate allograft in transverse maxillary defects. This surgical approach was performed in five patients (4 females and 1 male, aged 20 to 37 years). Clinical results show that sufficient hard tissue was formed to allow implant born rehabilitation in the former insufficient bone sites. Histological evaluation revealed small amounts of newly formed bone with a predominance of collagen fibrous tissue and mature bone with very little...
Tipo: Journal article Palavras-chave: Bone regeneration; Maxilla; Dental implant; Bone defect; Biomaterials.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000100057
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Bone Healing in Transverse Maxillary Defects with Different Surgical Procedures Using Anorganic Bovine Bone in Humans International Journal of Morphology
Beltrán,Victor; Matthijs,Andries; Borie,Eduardo; Fuentes,Ramón; Valdivia-Gandur,Iván; Engelke,Wilfried.
The centripetal resorption of maxilla is a continuous process after tooth loss. For treatment of deficient bone sites, autologous bone grafts may be used, as an alternative, biomaterials can be applied which do not require intra- or extraoral donor sites. The present report we describe the use of anorganic bovine bone (ABB) based on three case reports under different modes: Membrane, rigid barrier and connective tissue graft. Clinical results show that under all conditions, sufficient hard tissue was formed to allow implant born rehabilitation in the former insufficient bone sites. Histologic evaluation revealed trabecular bone in an almost mature matrix with resting particles of ABB. Depending on the original site situation, two step rigid occlusive...
Tipo: Journal article Palavras-chave: Bone regeneration; Maxilla; Dental implant; Bone defect; Biomaterials.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100011
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Building bone tissue: matrices and scaffolds in physiology and biotechnology BJMBR
Riminucci,M.; Bianco,P..
Deposition of bone in physiology involves timed secretion, deposition and removal of a complex array of extracellular matrix proteins which appear in a defined temporal and spatial sequence. Mineralization itself plays a role in dictating and spatially orienting the deposition of matrix. Many aspects of the physiological process are recapitulated in systems of autologous or xenogeneic transplantation of osteogenic precursor cells developed for tissue engineering or modeling. For example, deposition of bone sialoprotein, a member of the small integrin-binding ligand, N-linked glycoprotein family, represents the first step of bone formation in ectopic transplantation systems in vivo. The use of mineralized scaffolds for guiding bone tissue engineering has...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Extracellular matrix; Bone matrix; Bone formation; Biomaterials; Tissue engineering.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000800008
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Comparison of Bone Graft Healing Between Autogenous Bone, Blood Clot and Anorganic Bovine Bone Matrix: Radiographic and Histological Analyses International Journal of Morphology
Olate,Sergio; Duque Netto,Henrique; Klüppel,Leandro E; Vásquez,Bélgica; Miranda Chaves,Maria das Graças A; del Sol,Mariano.
Surgical procedures involving the rehabilitation of the maxillofacial region frequently require use of bone grafts. Bone graft follow-up is generally done through clinical analysis and especially through image tests, although few studies specifically correlate both. The object of this research was to establish a relation between radiographic exams and the bone repair process stage in created defect with autogenous bone, blood clot and anorganic bovine bone matrix. Three 8 mm diameter defects were performed in the parietal bone of 6 male adult beagle dogs, choosing the selected graft for each defects; 3 and 6 week period were used for radiographic and histological analyses. The result show that autogenous bone and blood clot were similar between...
Tipo: Journal article Palavras-chave: Autogenous bone; Biomaterials; Bone graft.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400018
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Development of alginate hydrogels active against adhesion of microalgae ArchiMer
Nassif, L. Abi; Rioual, S.; Trepos, Rozenn; Fauchon, M.; Farah, W.; Hellio, C.; Abboud, M.; Lescop, B..
Microorganisms have the ability to settle on nearly all man-made surfaces in contact with seawater and subsequently to form biofilm. Biofilms control and removal is necessary in the sectors of maritime transport, energy... In this work, we present the development of new pure calcium, zinc or copper alginate, but also mixed Ca/Cu and Ca/Zn alginate hydrogels. These materials have been evaluated for their potential inhibition of adhesion of two key biofilm-forming microalgae Halamphora coffeaeformis and Cylindrotheca closterium). All the tested materials have presented high adhesion inhibition about 80%). Copper-base materials present a high toxicity against H. coffeaeformis. Pure zinc alginate is also toxic for this strain. However, the addition of calcium...
Tipo: Text Palavras-chave: Biofilm; Adhesion; Alginate; Zinc; Biomaterials; Microalgae.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00605/71671/70168.pdf
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Development of VEGF-loaded PLGA matrices in association with mesenchymal stem cells for tissue engineering BJMBR
Rosa,A.R.; Steffens,D.; Santi,B.; Quintiliano,K.; Steffen,N.; Pilger,D.A.; Pranke,P..
The association of bioactive molecules, such as vascular endothelial growth factor (VEGF), with nanofibers facilitates their controlled release, which could contribute to cellular migration and differentiation in tissue regeneration. In this research, the influence of their incorporation on a polylactic-co-glycolic acid (PLGA) scaffold produced by electrospinning on cell adhesion and viability and cytotoxicity was carried out in three groups: 1) PLGA/BSA/VEGF; 2) PLGA/BSA, and 3) PLGA. Morphology, fiber diameter, contact angle, loading efficiency and controlled release of VEGF of the biomaterials, among others, were measured. The nanofibers showed smooth surfaces without beads and with interconnected pores. PLGA/BSA/VEGF showed the smallest water contact...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Emulsion electrospinning; VEGF; Stem cells; PLGA; Biomaterials.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000900601
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Fibrin biopolymer as scaffold candidate to treat bone defects in rats J. Venom. Anim. Toxins incl. Trop. Dis.
Cassaro,Claudia Vilalva; Justulin Jr.,Luis Antonio; Lima,Patrícia Rodrigues de; Golim,Marjorie de Assis; Biscola,Natália Perussi; Castro,Mateus Vidigal de; Oliveira,Alexandre Leite Rodrigues de; Doiche,Danuta Pulz; Pereira,Elenize Jamas; Ferreira Jr.,Rui Seabra; Barraviera,Benedito.
ABSTRACT Background: Bone tissue repair remains a challenge in tissue engineering. Currently, new materials are being applied and often integrated with live cells and biological scaffolds. The fibrin biopolymer (FBP) proposed in this study has hemostatic, sealant, adhesive, scaffolding and drug-delivery properties. The regenerative potential of an association of FBP, biphasic calcium phosphate (BCP) and mesenchymal stem cells (MSCs) was evaluated in defects of rat femurs. Methods: Adult male Wistar rats were submitted to a 5-mm defect in the femur. This was filled with the following materials and/or associations: BPC; FBP and BCP; FBP and MSCs; and BCP, FBP and MSCs. Bone defect without filling was defined as the control group. Thirty and sixty days...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bone regeneration; Biomaterials; Fibrin sealant; Fibrin biopolymer; Biphasic calcium phosphate; Mesenchymal stem cells.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100320
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Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets International Journal of Morphology
Fuentes,Ramón; Oporto Venegas,Gonzalo; Olate,Sergio; Rojas Rauco,Mariana; Borie,Eduardo.
Within oral rehabilitation alveolar ridge preservation following extraction is important. This research study shows a histological, histochemical and histomorphometrical evaluation in two cases of post extraction ridge-socket preservation performed with FDBA. In two patients dental extraction procedures were performed and sockets were immediately filled with FDBA. Six months later a biopsy of grafted area was obtained and rehabilitated through dental implant. Grafted bone samples were treated for histological and histochemical analysis. Bone tissue area was measured. Laboratory analysis of three samples showed inactive bone surfaces, neither osteoblasts nor osteoclasts were found, only osteocyte and osteogenous cells were observed. These findings do not...
Tipo: Journal article Palavras-chave: Bone regeneration; Biomaterials; FDBA; Socket.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100047
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In vitro cultivation of canine multipotent mesenchymal stromal cells on collagen membranes treated with hyaluronic acid for cell therapy and tissue regeneration BJMBR
Wodewotzky,T.I.; Lima-Neto,J.F.; Pereira-Júnior,O.C.M.; Sudano,M.J.; Lima,S.A.F.; Bersano,P.R.O.; Yoshioka,S.A.; Landim-Alvarenga,F.C..
Support structures for dermal regeneration are composed of biodegradable and bioresorbable polymers, animal skin or tendons, or are bacteria products. The use of such materials is controversial due to their low efficiency. An important area within tissue engineering is the application of multipotent mesenchymal stromal cells (MSCs) to reparative surgery. The combined use of biodegradable membranes with stem cell therapy may lead to promising results for patients undergoing unsuccessful conventional treatments. Thus, the aim of this study was to test the efficacy of using membranes composed of anionic collagen with or without the addition of hyaluronic acid (HA) as a substrate for adhesion and in vitro differentiation of bone marrow-derived canine MSCs. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Collagen scaffolds; Biomaterials; Hyaluronic acid; Mesenchymal stromal cells; Tissue engineering; Cell culture.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200008
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In vivo biocompatibility of nanostructured Chitosan/Peo membranes Arq. Bras. Med. Vet. Zootec.
Vulcani,V.A.S.; Franzo,V.S.; Rabelo,R.E.; Rabbers,A.S.; Assis,B.M.; D'Ávila,M.A.; Antoni,S.M.B..
Electrospinning is a technique that allows the preparation of nanofibers from various materials. Chitosan is a natural and abundant easily obtained polymer, which, in addition to those features, proved to be biocompatible. This work used nanostructured chitosan and polyoxyethylene membranes as subcutaneous implants in Wistar rats to evaluate the biocompatibility of the material. Samples of the material and tissues adjacent to the implant were collected 7, 15, 30, 45 and 60 days post-implantation. Macroscopic integration of the material to the tissues was observed in the samples and slides for histopathological examination that were prepared. It was noticed that the material does not stimulate the formation of adherences to the surrounding tissues and that...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nanotechnology; Biomaterials; Electrospinning.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000401039
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In vivo biocompatibility of silicon dioxide nanofilm used as antimicrobial agent on acrylic surface Anais da ABC (AABC)
LACERDA-SANTOS,ROGÉRIO; LIMA,ANTONIA BÁRBARA L.; PENHA,ELIZANDRA S. DA; SANTOS,ANTONIELSON DOS; CARVALHO,FABÍOLA G.; PITHON,MATHEUS M.; DANTAS,ANTÔNIO FLÁVIO M..
Abstract the focus ofthis study was to testthe hypothesisthatthere would be no difference betweenthe biocompatibility of silicon dioxide nanofilms used as antimicrobial agents. Sixty male Wistar rats were divided into 4 groups (n=15): Group C (Control,Polyethylene), Group AR (Acrylic Resin), Group NP (Acrylic Resin coated with NP-Liquid), Group BG (Acrylic Resin coated with Bacterlon).the animals were sacrificed with 7,15 and 30 days and tissues analyzed as regardsthe events of inflammatory infiltrate, edema, necrosis, granulation tissue, mutinucleated giant cells, fibroblasts and collagen. Kruskal-Wallis and Dunn tests was used (P<0.05). Intense inflammatory infiltrate was shown mainly in Groups BG and AR, with significant difference from Control Group...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biomaterials; Biocompatibility; Dentistry; Inflammation.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100910
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Main biological and synthetic materials applied in abdominal wall reconstructive surgeries in Veterinary Medicine: literature review MV&Z
Azevedo, Rafael Augusto de; Stopiglia, Angelo João.
Researches for the ideal material for abdominal wall reconstructive procedures in Veterinary Medicine remains constant. Synthetic and biological materials are routinely studied, regarding the ability of abdominal support and reactivity of the host, both of them present advantages and disadvantages. This review analyzes the main characteristics of synthetic and biological materials currently in use, in order to compare the two of them. It was observed that biological materials have less reactivity by the host, but the strength of the synthetic materials is higher, even though, more expensive. The effort and research for the ideal material should remain active because the ideal one has not been found yet.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Abdomen; Biomaterials; Muscle abdômen; Biomateriais; Músculo.
Ano: 2018 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/37780
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Medical applications of shape memory alloys BJMBR
Machado,L.G.; Savi,M.A..
Shape memory alloys (SMA) are materials that have the ability to return to a former shape when subjected to an appropriate thermomechanical procedure. Pseudoelastic and shape memory effects are some of the behaviors presented by these alloys. The unique properties concerning these alloys have encouraged many investigators to look for applications of SMA in different fields of human knowledge. The purpose of this review article is to present a brief discussion of the thermomechanical behavior of SMA and to describe their most promising applications in the biomedical area. These include cardiovascular and orthopedic uses, and surgical instruments.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Shape memory alloys; Biomaterials.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000600001
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PRELIMINARY FEASIBILITY ANALYSIS FOR AN INTEGRATED BIOMATERIALS AND ETHANOL BIOREFINERY USING WHEAT STRAW FEEDSTOCK AgEcon
Leistritz, F. Larry; Senechal, Donald M.; Stowers, Mark D.; McDonald, William F.; Saffron, Chris M.; Hodur, Nancy M..
Biobased products and fuels appear to have a very bright future. A consortium led by NDSU is currently engaged in a project that would use cellulose nanofibers derived from wheat straw to make a product that could substitute for fiberglass and plastics in many applications, including automotive parts. The work described here analyzes the economic value of producing cellulose nanowhiskers (CNW) as a co-product in an ethanol biorefinery. An ASPEN Plus-based process model was developed to evaluate ethanol production from wheat straw. The base case model generated 54.418 million gallons per year (MGPY) of denatured ethanol, using approximately 900,000 tons per year of wheat straw feedstock. The capital cost was estimated at $185 million. Total operating...
Tipo: Working or Discussion Paper Palavras-chave: Biomass; Biomaterials; Ethanol; Wheat straw; Cellulose nanowhiskers (CNW); Resource /Energy Economics and Policy.
Ano: 2006 URL: http://purl.umn.edu/23500
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Properties of films obtained from biopolymers of different origins for skin lesions therapy BABT
Bellini,Márcia Zilioli; Oliva-Neto,Pedro de; Moraes,Ângela Maria.
In this study, the effects of the origin of xanthan used, in combination with chitosan, to prepare films for the treatment of skin lesions were evaluated. The characteristics of the films obtained with xanthan commercially available for the food industry sector and xanthan originated from a fermentation process conducted in a pilot plant were compared. Results showed that the source did not strongly interfere in many of the properties of the films, such as the mechanical properties, cytotoxicity to L929 cells, absorption of simulated body fluid and culture medium, stability in water and saline solution. Hence, even though the properties of biopolymers of different sources might vary, the films prepared with two distinct types of xanthan gum could be...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biomaterials; Biopolymers; Films; Membranes; Properties and characterization; Biomedical applications.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000200289
Registros recuperados: 26
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