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Registros recuperados: 111
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A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers BJID
Carlesse,Fabianne; Daudt,Liane Esteves; Seber,Adriana; Dutra,Álvaro Pimenta; Melo,Analy Salles de Azevedo; Simões,Belinda; Macedo,Carla Renata Donato; Bonfim,Carmem; Benites,Eliana; Gregianin,Lauro; Batista,Marjorie Vieira; Abramczyk,Marcelo; Tostes,Vivian; Lederman,Henrique Manoel; Lee,Maria Lúcia de Martino; Loggetto,Sandra; Castro Junior,Cláudio Galvão de; Colombo,Arnaldo Lopes.
ABSTRACT In the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in children with hematologic cancer and those who underwent hematopoietic stem-cell transplantation. All major multicenter studies designed to characterize the epidemiology of IFDs in children with cancer, as well as all randomized clinical trials addressing empirical and targeted antifungal therapy were reviewed. In the absence of randomized clinical trials, the best evidence available to support the recommendations were selected. Algorithms for early...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fungal infections; Children; Cancer.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000600395
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A prospective observational cohort study to assess the incidence of acute otitis media among children 0-5 years of age in Southern Brazil BJID
Lanzieri,Tatiana M.; Cunha,Clóvis Arns da; Cunha,Rejane B.; Arguello,D. Fermin; Devadiga,Raghavendra; Sanchez,Nervo; Barria,Eduardo Ortega.
Abstract Objectives: To estimate acute otitis media incidence among young children and impact on quality of life of parents/caregivers in a southern Brazilian city. Methods: Prospective cohort study including children 0-5 years of age registered at a private pediatric practice. Acute otitis media episodes diagnosed by a pediatrician and impact on quality of life of parents/caregivers were assessed during a 12-month follow-up. Results: During September 2008-March 2010, of 1,136 children enrolled in the study, 1074 (95%) were followed: 55.0% were ≤2 years of age, 52.3% males, 94.7% white, and 69.2% had previously received pneumococcal vaccine in private clinics. Acute otitis media incidence per 1000 person-years was 95.7 (95% confidence interval:...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Acute otitis media; Children; Incidence; Quality of life.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000400468
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A Report on Socioeconomic Attributes and Gender Inequality in Kondh-Dominated Villages: A Comparative Analysis of Tribals and Non-Tribals in the Phulbani District, Orissa, India AgEcon
Tisdell, Clement A.; Roy, Kartik C.; Ghose, Ananda.
Reports on results of a survey, completed in 2000, of wives in three villages in the Phulbani district, Orissa, India. These villages are dominated by the Kondh scheduled tribe but some also contain members of the scheduled caste, called Dombs in Orissa. The article reports on the total responses and comparative responses of these groups to a structured questionnaire. The article provides background information for the villages surveyed, and reports information in relation to wives and their families about property rights, assets and incomes, economic conditions and survival strategies, aspects of credit, production and marketing, social dynamics and education. In addition, children’s affairs, including the treatment and entitlements of female and male...
Tipo: Working or Discussion Paper Palavras-chave: Gender Inequality; Children; India; Community/Rural/Urban Development; Institutional and Behavioral Economics.
Ano: 2002 URL: http://purl.umn.edu/100213
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Acceptance of fish hamburgers in school meals in the Southwest Region of Paraná, Brazil Ciênc. Tecnol. Aliment.
BREDA,Leandra Schuastz; BELUSSO,Anne Caroline; NOGUEIRA,Barbara Arruda; CAMARGO,Guilherme Holub; MITTERER-DALTOÉ,Marina Leite.
Abstract The regular consumption of fish provides health gains for people, and its introduction in school meals is an important strategy to insert the habit of consuming this food by a population. Thus the objective of this study was to verify the acceptance of fish, presented in the form of hamburger, by children in municipal primary schools in the town of Pato Branco, Brazil, in which the school cooks had been trained to produce fish hamburgers. Acceptance was evaluated using a hedonic scale with 5 facial classifications (1 = disliked extremely to 5 = liked extremely). Students of both genders from 5 to 10 years of age (n = 142) were served the hamburgers for their midday meal, representing the protein portion of the meal. The results were analyzed by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fish; Hamburger; School meals; Acceptance; Children.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612017000500094
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Acute cor pulmonale due to lymphocytic interstitial pneumonia in a child with AIDS BJID
Moreira-Silva,Sandra Fagundes; Moreno,Linda Marly C.; Dazzi,Mariana; Freire,Consuelo Maria Caiafa; Miranda,Angelica Espinosa.
BACKGROUND: Acute cor pulmonale is a clinical syndrome with signs of right-sided heart failure resulting from sudden increase of pulmonary vascular resistance. CASE PRESENTATION: A five-year-old male, infected by human immunodeficiency virus (HIV), was admitted at the division of infectious diseases of this hospital with cough, tachydyspnea, fever, and breathing difficulty. Computed tomography scan showed ground-glass opacities, cystic lesions, and bronchiectasis. The patient had nasal flaring, intercostal and subcostal retractions, and keeled chest. Abdomen was depressible; liver was 3 cm from the right-costal border, while spleen was 6 cm from the left-costal border. Echocardiogram examinations showed signs of acute cor pulmonale characterized by...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Acquired immunodeficiency syndrome; Adult; Children; Respiratory tract infections.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300013
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Acute disseminated paracoccidioidomycosis in a 3 year-old child BJID
Grossklaus,Daciene de Arruda; Tadano,Tomoko; Breder,Sandra Assis; Hahn,Rosane Christine.
Clinical cases involving paracoccidioidomycosis in children, diagnosed in Mato Grosso State, in the central western region of Brazil, are rare despite the state being classified with a moderate to high incidence. We describe a clinical case of infant acute disseminated Paracoccidioidomycosis in Mato Grosso State, Brazil, highlighting the importance of early differential diagnosis from other severe pathologies, thus contributing to the survival of compromised patients. A 3 year-old male child, weighing 12.8 Kg, originating from Vila Rica, MT, Brazil. The patient presented intermittent 40ºC fever evolving over 40 days, dry cough and painless bilateral cervical adenomegaly, showing no signs of inflammation. This was associated with diarrhea, distension and...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Acute paracoccidioidomycosis; Children; Antifungal.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000300018
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Acute liver failure complicating viral hepatitis A BJID
Diniz-Santos,Daniel Rui; Melo,Maria Clotildes Nunes de; Melo,Rita Franca; Silva,Luciana Rodrigues.
Hepatitis A is one of the most frequent infectious liver diseases affecting children worldwide. The disease is usually mild and self-limited, and complications are very rare. Nevertheless, hepatitis A can sometimes cause acute liver failure (ALF), a severe, life-threatening condition. Herein is reported a case of a child who presented ALF during a course of hepatitis A. The need for early identification of possible ALF cases among hepatitis A patients, and for effective ways of evaluating such a possibility, are discussed. We also emphasize the importance of prevention measures, especially vaccination.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Hepatitis A; Acute liver failure; Children.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000200009
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Adherence and virulence genes of Escherichia colifrom children diarrhoea in the Brazilian Amazon BJM
Benevides-Matos,Najla; Pieri,Fabio A.; Penatti,Marilene; Orlandi,Patrícia P..
The bacterial pathogen most commonly associated with endemic forms of childhood diarrhoea is Escherichia coli. Studies of epidemiological characteristics of HEp-2 cell-adherent E. coli in diarrhoeal disease are required, particularly in developing countries. The aim of this study was evaluate the presence and significance of adherent Escherichia coli from diarrhoeal disease in children. The prevalence of LA, AA, and DA adherence patterns were determined in HEp-2 cells, the presence of virulence genes and the presence of the O serogroups in samples obtained from 470 children with acute diarrhoea and 407 controls in Porto Velho, Rondônia, Brazil. E. coli isolates were identified by PCR specific for groups of adherent E. coli. Out of 1,156 isolates obtained,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Enteroadherent Escherichia coli; Diarrhoea; Children.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100131
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Adherence to antiretroviral therapy of Brazilian HIV-infected children and their caregivers BJID
Ricci,Gabriela; Netto,Eduardo Martins; Luz,Estela; Rodamilans,Cynthia; Brites,Carlos.
Abstract Background Successful treatment of HIV-positive children requires a high level of adherence (at least 95%) to highly active antiretroviral therapy. Adherence is influenced by factors related to the child and caregivers. Objectives To evaluate children and caregivers characteristics associated to children's adherence. Methods Cross-sectional study, from September 2013 to June 2015, comprising a sample of caregivers of perinatally HIV-infected children, in the age group of 1–12 years, under antiretroviral therapy for at least 6 months and on follow-up in two AIDS reference centers in Salvador, Bahia. Caregiver self-reports were the sole source of 4 days adherence and sociodemographic information. Study participants who reported an intake >95%...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adherence; Antiretroviral therapy; Children; Caregivers.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500429
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Agenesis of Palmaris Longus Muscle in Selected Population of School Children in Nigeria International Journal of Morphology
Adejuwon,Sunday Adeyemi; Salawu,Oyetunde Timothy; Ajibola,Bosede.
The aim of this study is to evaluate the prevalence of agenesis of palmaris longus muscle tendon among school children in Ogun state, Southwestern Nigeria and also, to verify the symmetry of the agenesis of the muscle in relation to sex. The presence of the palmaris longus muscle tendon was determined in 564 individuals, 285 male and 279 female, with age varying from 2 to 20 years old. Four different tests were used; Schaeffer's test, Thompson's test, Mishra's test 1 and Pushpakumar's "two-finger sign" method. The data obtained were further analyzed statistically and the agenesis of palmaris muscle was found to be 26.7% (unilateral 13.0%; bilateral 13.7%). Prevalence was higher in female (32.3%) than male (21.4%) (P>0.05). Besides, we observed higher...
Tipo: Journal article Palavras-chave: Agenesis; Children; Palmaris longus muscle; Prevalence.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000400052
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AN ECONOMIC MODEL OF WIC, THE INFANT FORMULA REBATE PROGRAM, AND THE RETAIL PRICE OF INFANT FORMULA AgEcon
Prell, Mark A..
This report develops an economic model that provides the theoretical framework for the econometric analyses presented in the report's companion volume, WIC and the Retail Price of Infant Formula (FANRR-39). The model examines supermarket retail prices for infant formula in a local market area, and identifies the theoretical effects of the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and its infant formula rebate program. Special attention is given to the rebate program's sole-source procurement system by which a single manufacturer becomes a State's "contract brand"-the State's one supplier of formula to WIC infants-in exchange for paying rebates to WIC. When a manufacturer's brand is designated a State's contract brand,...
Tipo: Report Palavras-chave: WIC program; Infant formula; Cost containment; Rebates; Food package costs; Special Supplemental Nutrition Program for Women; Infants; Children; Child nutrition; Food assistance; Food Security and Poverty.
Ano: 2004 URL: http://purl.umn.edu/33879
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An improved HPLC method for the quantitation of 6-mercaptopurine and its metabolites in red blood cells BJMBR
Oliveira,B.M.; Romanha,A.J.; Alves,T.M.A.; Viana,M.B.; Zani,C.L..
A procedure is described for the rapid determination of the intra-erythrocyte concentration of 6-mercaptopurine (6-MP) and its metabolites, 6-thioguanine nucleotides (6-TGN) and 6-methylmercaptopurine (6-MMP). Erythrocytes (8 x 10(8) cells) in 350 µl Hanks solution containing 7.5 mg dithiothreitol were treated with 50 µl 70% perchloric acid. The precipitate was removed by centrifugation (13,000 g) and the supernatant hydrolyzed at 100°C for 45 min. After cooling, 100 µl was analyzed directly by HPLC using a Radialpack Resolve C18 column eluted with methanol-water (7.5:92.5, v/v) containing 100 mM triethylamine. 6-TG, 6-MP and the hydrolysis product of 6-MMP, 4-amino-5-(methylthio)carbonyl imidazole, were monitored at 342, 322 and 303 nm using a Shimadzu...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute lymphoblastic; Ukemia; Chemotherapy; 6-Mercaptopurine; Compliance; Children.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000500004
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Antibiotics for the empirical treatment of acute infectious diarrhea in children BJID
Diniz-Santos,Daniel R.; Silva,Luciana R.; Silva,Nanci.
While the routine use of antibiotics for infectious diarrhea in children must be avoided, because it brings little benefit in most cases and is associated with the risk of increasing antimicrobial resistance, selected cases may require antimicrobial therapy, and the choice of the antimicrobial agent often has to be made empirically. Physicians prescribing antimicrobials in such a setting have not only to be aware of the most likely pathogens, but also of their characteristic antimicrobial susceptibility pattern and the safety profile of the various drugs. We reviewed the literature on the use of ampicillin, beta-lactamase inhibitors, trimethoprim-sulfamethoxazole, chloramphenicol, tetracyclines, nalidixic acid, fluoroquinolones, third-generation...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diarrhea; Antibiotics; Children; Treatment.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000300011
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Antimicrobial susceptibility and fluctuations in clonal complexes of serogroup 6 Streptococcus pneumoniae isolates collected from children in Beijing, China, between 1997 and 2016 BJM
Shi,Wei; Liu,Ying; Meng,Qinghong; Yuan,Lin; Gao,Wei; Yao,Kaihu.
ABSTRACT This study examined the antimicrobial susceptibility patterns and clonal complex (CC) characteristics of serogroup 6 Streptococcus pneumoniae isolates collected from children in Beijing, China, between 1997 and 2016. Serotypes were determined using the Quellung reaction, and the antimicrobial susceptibility profiles of the isolates were determined using the disc-diffusion method or by E-test. Sequence types (STs) were assigned based on multilocus sequence typing. A total of 250 isolates were examined, with 55.2%, 30.0%, 12.8%, and 2.0% of isolates identified as serotypes 6A, 6B, 6C, and 6D, respectively. All of the isolates were susceptible to levofloxacin and vancomycin, and the non-suceptibitility rate to penicillin was 41.6%. Eighty-two...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptococcus pneumoniae; Children; Antimicrobial susceptibility; Clonal complex (CC); Sequence type (ST).
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000400891
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APOA1/C3/A4 gene cluster variability and lipid levels in Brazilian children BJMBR
França,E. de; Alves,J.G.B.; Hutz,M.H..
Genetic studies have suggested that polymorphisms of genes coding for apolipoproteins are significant determinants of serum lipoprotein and lipid levels in adults. However, only a few studies have investigated the association of these polymorphisms in children. Therefore, in the present investigation we studied the distribution of APOA1 -75 G>A, +83 C>T, APOC3 -482 C>T, -455 T>C and 3238 C>G, and APOA4 Q360H and T347S polymorphisms and their influence on plasma lipoprotein levels in children from a Brazilian northeastern admixed population. The seven polymorphic sites were genotyped in 414 children aged 5 to 15 years (mean 8.9 ± 2.9). The genotypes of the seven polymorphic sites were assessed by PCR-RFLP methods. The frequencies of the less...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Apolipoproteins; Gene variants; Lipid levels; Children.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400006
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ApoE polymorphisms and diarrheal outcomes in Brazilian shanty town children BJMBR
Oriá,R.B.; Patrick,P.D.; Oriá,M.O.B.; Lorntz,B.; Thompson,M.R.; Azevedo,O.G.R.; Lobo,R.N.B.; Pinkerton,R.F.; Guerrant,R.L.; Lima,A.A.M..
A series of studies have shown that the heavy burdens of diarrheal diseases in the first 2 formative years of life in children living in urban shanty towns have negative effects on physical and cognitive development lasting into later childhood. We have shown that APOE4 is relatively common in shanty town children living in Brazil (13.4%) and suggest that APOE4 has a protective role in cognitive development as well as weight-for-height in children with heavy burdens of diarrhea in early childhood (64/123; 52%), despite being a marker for cognitive decline with Alzheimer’s and cardiovascular diseases later in life. APOE2 frequency was higher among children with heaviest diarrhea burdens during the first 2 years of life, as detected by PCR using the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Apolipoprotein E; Malnutrition; Diarrhea; Children.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300005
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Aspergillus niger – a possible new etiopathogenic agent in Tinea capitis? Presentation of two cases BJID
Chokoeva,Anastasiya Atanasova; Zisova,Liliya; Chorleva,Kristina; Tchernev,Georgi.
Abstract Tinea capitis is generally considered as the most frequent fungal infection in childhood, as it accounts for approximately 92% of all mycosis in children. The epidemiology of this disease varies widely ranging from antropophillic, zoophilic, and geophillic dermatophytes, as the main causative agent in different geographic areas, depending on several additional factors. Nowadays, the etiology is considered to vary with age, as well with gender, and general health condition. The former reported extraordinary Tinea capitis case reports have been replaced by original articles and researches dealing with progressively changing patterns in etiology and clinical manifestation of the disease. This fact is indicative that under the umbrella of the...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Tinea capitis; Children; Etiology; Molds.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000300015
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Assessing subtypes and drug resistance mutations among HIV-1 infected children who failed antiretroviral therapy in Kelantan, Malaysia BJID
Mohamad,Suharni; Deris,Zakuan Zainy; Yusoff,Nik Khairulddin; Ariffin,Tg Ahmad Akram Tg Mohd; Shueb,Rafidah Hanim.
Antiretroviral (ARV) therapy has dramatically reduced morbidity and mortality in human immunodeficiency virus 1 (HIV-1) infected children. However, development of ARV resistance in these children is a major public health problem due to lack of availability of and access to new drugs. This study was conducted in order to identify circulating HIV subtypes and recombinant forms and evaluate the drug resistance mutation patterns in 18 HIV-1 infected children failing ARV treatment in Kelantan, Malaysia. Genotyping for codon 1-99 of protease (PR) and 1-250 of reverse transcriptase (RT) were performed by polymerase chain reaction (PCR) amplification and DNA sequencing. Subsequently, these were phylogenetically analyzed to determine the subtypes. CRF33_01B (44.4%)...
Tipo: Info:eu-repo/semantics/other Palavras-chave: HIV-1 subtype; Resistance mutation; Children.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300012
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Association between serotonin 2C receptor gene (HTR2C) polymorphisms and psychopathological symptoms in children and adolescents BJMBR
Paes,L.A.; Torre,O.H. Della; Henriques,T.B.; de Mello,M.P.; Celeri,E.H.R.V.; Dalgalarrondo,P.; Guerra Júnior,G.; dos Santos Júnior,A..
Serotonin 2C receptors (5HT2C) are involved in serotonin-driven dynamic equilibrium adjustments responsible for homeostatic stability in brain structures that modulate behavior and emotions. Single nucleotide polymorphisms (SNPs) from the serotonin 2C receptor gene (HTR2C) have been associated with several neurological and mental disorders, including abnormalities in cognitive and emotional processes. The aim of this study was to evaluate the association between the rs6318 SNP of the HTR2C gene and behavioral characteristics exhibited by children and adolescents based on the Child Behavior Checklist (CBCL/6-18) inventory. Eighty-five psychiatric outpatients between 8 and 18 years of age underwent genotyping of the rs6318 SNP. The CBCL/6-18 scale was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Genetic polymorphism; Serotonin; CBCL/6-18; Children; Adolescents; HTR2C.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800611
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Association of X4 tropism with disease progression in antiretroviral-treated children and adolescents living with HIV/AIDS in São Paulo, Brazil BJID
Almeida,Flávia Jacqueline; Zaparoli,Mayra Simioni; Moreira,Denise Helena; Cavalcanti,Jaqueline de Souza; Rodrigues,Rosangela; Berezin,Eitan Naaman; Ferreira,João Leandro de Paula; Sáfadi,Marco Aurélio Palazzi; Brígido,Luis Fernando de Macedo.
Management of children with HIV/AIDS is specially challenging. Age-related issues do not allow for direct transposition of adult observations to this population. CXCR4 tropism has been associated with disease progression in adults. The geno2pheno web-base is a friendly tool to predict viral tropism on envelope V3 sequences, generating a false positive rate for a CXCR4 prediction. We evaluated the association of HIV-1 tropism prediction with clinical and laboratory outcome of 73 children with HIV/AIDS in São Paulo, Brazil. The CXCR4 tropism was strongly associated with a lower (nadir) CD4 documented during follow-up (p < 0.0001) and with disease severity (clinical event and/or CD4 below 200 cells/mm3) at the last observation, using commonly applied...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV-1; Children; Viral tropism; Disease progression.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000300300
Registros recuperados: 111
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