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Identification of new Corynebacterium pseudotuberculosis antigens by immunoscreening of gene expression library. Repositório Alice
GALVÃO, C. E.; FRAGOSO, S. P.; OLIVEIRA, C. E. de; FORNER, O.; PEREIRA, R. R. B.; SOARES, C. O.; ROSINHA, G. M. S..
bitstream/item/166571/1/Identification-of-new-Corynebacterium.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Corynebacterium pseudotuberculosis; Caseous lymphadenitis; Sheep; Gene expression; DNA vaccines.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1079448
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Membrane and envelope virus proteins co-expressed as lysosome associated membrane protein (LAMP) fused antigens: a potential tool to develop DNA vaccines against flaviviruses Anais da ABC (AABC)
Dhalia,Rafael; Maciel Jr.,Milton; Cruz,Fábia S.P.; Viana,Isabelle F.T.; Palma,Mariana L.; August,Thomas; Marques Jr.,Ernesto T.A..
Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even rare fatal reactions. Given this scenario, the developent of alternative vaccination strategies such as DNA-based vaccines encoding specific flavivirus sequences are being considered. Endogenous cytoplasmic antigens, characteristically plasmid DNA-vaccine encoded, are mainly presented to the immune system through Major Histocompatibility Complex class I - MHC I molecules. The MHC I presentation via is mostly associated with a cellular cytotoxic response and often do not elicit a satisfactory humoral...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dengue; West Nile; Yellow fever; Lysosome-Associated Membrane Protein - LAMP; DNA vaccines.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000400005
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New vaccine strategies against enterotoxigenic Escherichia coli: I: DNA vaccines against the CFA/I fimbrial adhesin BJMBR
Alves,A.M.B.; Lásaro,M.O.; Almeida,D.F.; Ferreira,L.C.S..
Stimulation of the mammalian immune system by administration of plasmid DNA has been shown to be an important approach for vaccine development against several pathogens. In the present study we investigated the use of DNA vaccines to induce immune responses against an enteric bacterial pathogen, enterotoxigenic Escherichia coli (ETEC). Three plasmid vectors encoding colonization factor antigen I (CFA/I), an ETEC fimbrial adhesin, were constructed. Eukaryotic cells transfected with each of these plasmids expressed the heterologous antigen in different compartments: bound to the cytoplasmic membrane (pRECFA), accumulated in the cytoplasm (pPolyCFA) or secreted to the outside medium (pBLCFA). BALB/c mice were intramuscularly (im) inoculated with purified...
Tipo: Info:eu-repo/semantics/article Palavras-chave: DNA vaccines; ETEC; Diarrheal disease; CFA/I fimbriae.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000200011
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