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Antioxidant capacity in relationship to serum lipid peroxides levels in healthy elderly of Mexico City ABCL
Sánchez-Rodríguez,Martha A.; Retana-Ugalde,Raquel; Ruiz-Ramos,Mirna; Mendoza-Núñez,Víctor Manuel.
The aging is one of the factors that cause decrease in the antioxidant capacity. Likewise, it has been proposed that subjects exposed permanently to air pollution develop deficient antioxidant capacity to oxidative stress (OxS). This study aimed to analyze the antioxidant capacity against elevated lipid peroxides in healthy elderly of Mexico City. 105 adults (44 ± 10.8 years) and 126 elderly subjects were studied (68 ± 7.1 years); residents of Mexico City (clinically healthy, non-smokers, non-vitamin supplement takers) who had lived in the city for >10 years. Plasma lipoperoxides (LPO), total antioxidant status (TAS), the activity of red blood cells superoxide dismutase (SOD), and plasma glutathione peroxidase (GPx), were studied in all subjects. LPO...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adaptation to oxidative stress; Total antioxidant status; Elderly people; Pollution; Superoxide dismutase; Glutathione peroxidase.
Ano: 2004 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572004000200007
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Can Triamcinolone acetonide, platelet-rich plasma, and pentosan polysulfate sodium induce oxidative stress in cultured equine chondrocytes? Ciência Rural
Palma,Heloisa Einloft; Gallio,Miguel; Silva,Gabriele Biavaschi da; Cantarelli,Camila; Wolkmer,Patrícia; Salazar,Rodrigo Fernando dos Santos; Wergutz,Julien; Krause,Luciana Maria Fontanari; Krause,Alexandre; Brass,Karin Erica; Corte,Flavio Desessards De La.
ABSTRACT: Progressive deterioration and loss of articular cartilage are the final degenerative events common to osteoarthritis (OA). Reactive oxygen species (ROS) play an important role in this chondrocyte catabolic activity, leading to cell death and matrix components breakdown. Intra-articular corticosteroid injections such as triamcinolone acetonide have been used to control pain and inflammation associated with OA. New treatments for OA, platelet-rich plasma and pentosan polysulphate sodium have also been used and further investigations are necessary to determine their safety in joint cells. In this in vitro study, the use of these three substances (triamcinolone acetonide, platelet-rich plasma, and pentosan polysulphate sodium) in healthy...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant enzymes; Catalase; Glutathione peroxidase; Lipid peroxidation.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000700602
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Changes in the TBARs content and superoxide dismutase, catalase and glutathione peroxidase activities in the lymphoid organs and skeletal muscles of adrenodemedullated rats BJMBR
Pereira,B.; Costa-Rosa,L.F.B.P.; Bechara,E.J.H.; Newsholme,P.; Curi,R..
Thiobarbituric acid reactant substances (TBARs) content, and the activities of glucose-6-phosphate dehydrogenase (G6PDh), citrate synthase (CS), Cu/Zn- and Mn-superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPX) were measured in the lymphoid organs (thymus, spleen, and mesenteric lymph nodes (MLN)) and skeletal muscles (gastrocnemius and soleus) of adrenodemedullated (ADM) rats. The results were compared with those obtained for sham-operated rats. TBARs content was reduced by adrenodemedullation in the lymphoid organs (MLN (28%), thymus (40%) and spleen (42%)) and gastrocnemius muscle (67%). G6PDh activity was enhanced in the MLN (69%) and reduced in the spleen (28%) and soleus muscle (75%). CS activity was reduced in all tissues (MLN...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epinephrine; Lymphoid organs; Superoxide dismutase; Catalase; Glutathione peroxidase; TBARs.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000600016
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Dietary levels and sources of selenium for post weaning piglets Ciência Rural
Oliveira,Tiago Ferreira Birro; Bertechini,Antônio Gilberto; Philomeno,Renato; Silva,Vanessa Avelar.
ABSTRACT: An experiment was conducted to study the effects of two sources and dietary levels of selenium (Se) on performance, Se concentration and glutathione peroxidase activity in plasma and liver of piglets post weaning. A total of 126 weaned pigs male and female Large White × Landrace, at average body weight of 7.2±0.67kg were allotted to seven treatments in a randomized block design, with two Se sources (organic and inorganic), inclusion levels, two levels for the inorganic source (0.30 and 0.60ppm) and four for the organic source (0.15, 0.30, 0.45 and 0.60ppm) and one control diet without Se supplementation containing 0.095ppm, and six replicates of three animals per pen. The experimental period was 35 days post-weaning. The organic source contained...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Enzyme activity; Glutathione peroxidase; Hepatic selenium; Plasmatic selenium.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001200653
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Effect of an aqueous extract of Scoparia dulcis on blood glucose, plasma insulin and some polyol pathway enzymes in experimental rat diabetes BJMBR
Latha,M.; Pari,L..
The effects of an aqueous extract of the plant Scoparia dulcis (200 mg/kg) on the polyol pathway and lipid peroxidation were examined in the liver of streptozotocin adult diabetic male albino Wistar rats. The diabetic control rats (N = 6) presented a significant increase in blood glucose, sorbitol dehydrogenase, glycosylated hemoglobin and lipid peroxidation markers such as thiobarbituric acid reactive substances (TBARS) and hydroperoxides, and a significant decrease in plasma insulin and antioxidant enzymes such as glutathione peroxidase (GPx), glutathione-S-transferase (GST) and reduced glutathione (GSH) compared to normal rats (N = 6). Scoparia dulcis plant extract (SPEt, 200 mg kg-1 day-1) and glibenclamide (600 µg kg-1 day-1), a reference drug, were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Glutathione peroxidase; Glutathione-S-transferase; Insulin; Lipid peroxidation; Scoparia dulcis; Sorbitol dehydrogenase; Diabetes.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000400015
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Lipid peroxidation, detoxification capacity, and genome damage in mice after transplacental exposure to pharmaceutical drugs BJMBR
Markovic,D.; Katic,J.; Stojkovic,R.; Borovic,S.; Zarkovic,N.; Fucic,A..
Data on genome damage, lipid peroxidation, and levels of glutathione peroxidase (GPX) in newborns after transplacental exposure to xenobiotics are rare and insufficient for risk assessment. The aim of the current study was to analyze, in an animal model, transplacental genotoxicity, lipid peroxidation, and detoxification disturbances caused by the following drugs commonly prescribed to pregnant women: paracetamol, fluconazole, 5-nitrofurantoin, and sodium valproate. Genome damage in dams and their newborn pups transplacentally exposed to these drugs was investigated using the in vivo micronucleus (MN) assay. The drugs were administered to dams intraperitoneally in three consecutive daily doses between days 12 and 14 of pregnancy. The results were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Glutathione peroxidase; Malondialdehyde; Genome damage; Transplacental exposure.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001201014
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Myocardial antioxidant and oxidative stress changes due to sex hormones BJMBR
Barp,J.; Araújo,A.S.R.; Fernandes,T.R.G.; Rigatto,K.V.; Llesuy,S.; Belló-Klein,A.; Singal,P..
The purpose of the present study was to examine myocardial antioxidant and oxidative stress changes in male and female rats in the presence of physiological sex hormone concentrations and after castration. Twenty-four 9-week-old Wistar rats were divided into four groups of 6 animals each: 1) sham-operated females, 2) castrated females, 3) sham-operated males, and 4) castrated males. When testosterone and estrogen levels were measured by radioimmunoassay, significant differences were observed between the castrated and control groups (both males and females), demonstrating the success of castration. Progesterone and catalase levels did not change in any group. Control male rats had higher levels of glutathione peroxidase (50%) and lower levels of superoxide...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Catalase; Glutathione peroxidase; Lipid peroxidation; Superoxide dismutase.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000900008
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Oocyte aspiration and in vitro embryo production in Jersey cows with selenium-supplemented diet Arq. Bras. Med. Vet. Zootec.
Moraes,G.V.; Azevedo,J.R.; Carneiro,T.C.; Cavalieri,F.L.B.; Mataveli,M.; Rossi,R.M.; Santos,T.C..
The effects of selenium (Se) in Jersey cows' diet on the aspiration of oocytes and production of embryos in vitro were studied. Groups with five Jersey cows received 3.2mg or 9.6mg Se daily, provided in the feed concentrate. Six follicular aspirations were carried out every 15 days, using only the last 5. The oocytes were classified, and standard procedures were carried out for maturation, fertilization and cultivation. The total number of oocytes (35.11±2.65 vs 23.10±2.16) and degree 1 oocytes (11.61±2.65 vs 4.75±0.97) were higher in the group that received 9.6mg Se and the quantity of naked oocytes (3.23±0.87 vs 6.22±1.18) was lower in this group. The aspirated oocytes from the cows treated with 9.6mg Se/day resulted in higher (P<0.05) embryo...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cattle dairy; Antioxidant; Glutathione peroxidase; In vitro fertilization; Oocyte quality.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000400001
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Oxidative stress assessment by glutathione peroxidase activity and glutathione levels in response to selenium supplementation in patients with Mucopolysaccharidosis I, II and VI Genet. Mol. Biol.
Oliveira-Silva,José Araújo de; Yamamoto,Joyce Umbelino Pinto; Oliveira,Renata Bernardes de; Monteiro,Vaneisse Cristina Lima; Frangipani,Beatriz Jurkiewcz; Kyosen,Sandra Obikawa; Martins,Ana Maria; D’Almeida,Vânia.
Abstract We assessed levels of plasma selenium (Se), selenoproteins and their change after Se supplementation in patients with mucopolysaccharidosis (MPS) types I, II and VI. This was done in a retrospective study of the medical records of 30 patients with MPS I (n=13), MPS II (n=9) and MPS VI (n=8) who were being treated with enzyme replacement therapy. As part of routine nutritional monitoring, Se levels were measured, revealing that 28 patients (93.3%) had values below the normal range. Therefore, they received supplementation for 12 months, and Se was measured after 6 and 12 months. Glutathione peroxidase (GPx) activity, total glutathione (GSHt), oxidized glutathione (GSSG) and reduced glutathione (GSH) were measured at baseline and 6 months after Se...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mucopolysaccharidosis; Oxidative stress; Selenium; Glutathione peroxidase.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000100001
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Selenium invoked antioxidant defense system in Azolla caroliniana plant Phyton
Hassan,AMA; Mostafa,EM.
Plants of Azolla caroliniana were treated with different selenium concentrations (0, 1, 2, 5, 7, 10 ppm) for seven days. Selenium (Se) content in Azolla plants increased significantly with increasing Se concentrations in the culture media up to 5 ppm. This indicated that Azolla plants were a good accumulator for Se. Selenium accumulation determined changes in Azolla biomass, doubling time and relative growth rates. Treatment of Azolla plants with low concentrations of Se (1 ppm) resulted in a significant increase in biomass. This was accompanied by a reduction in hydrogen peroxide and malondialdehyde (MDA) contents; the decrease percentages were 78% and 60%, respectively at 1 ppm Se in comparison with the control. At higher Se concentrations (>5 ppm),...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Selenium; Azolla caroliniana; Ascorbate; Glutathione; Antioxidant enzymes; Glutathione peroxidase.
Ano: 2016 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572016000200014
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Suplemento de Selenio en la respuesta fisiológica en corderos Colegio de Postgraduados
López Gutiérrez, Artemisa Guadalupe.
Se llevó a cabo un ensayo para evaluar el efecto de la concentración de Selenio (Se) en la dieta, así como la adición de Se orgánico, los tratamientos fueron: T1) Dieta testigo, la cual contenía 0.33 mg de Se y T2) Testigo + 300 mg de Selplex, con una concentración final de 0.93 mg de Se. El ensayo se llevo a cabo usando 8 corderos con un peso inicial de 30.5 ± 2.09 Kg, donde la concentración de Se en tejidos, la actividad de glutatión peroxidasa y balance de Se fueron analizados. El Se en la dieta no afecto la concentración se esté en tejidos para el grupo testigo así como para los animales que recibieron Se orgánico. La actividad de glutatión peroxidasa no tuvo diferencias entre tratamientos, aunque presento una tendencia (p=0.0011) a disminuir...
Palavras-chave: Selenio orgánico; Tejidos; Glutatión peroxidasa; Balance de selenio organic selenium; Tissues; Glutathione peroxidase; Selenium balance.
Ano: 2012 URL: http://hdl.handle.net/10521/897
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Suplemento de Selenio en la respuesta fisiológica en corderos Colegio de Postgraduados
López Gutiérrez, Artemisa Guadalupe.
Se llevó a cabo un ensayo para evaluar el efecto de la concentración de Selenio (Se) en la dieta, así como la adición de Se orgánico, los tratamientos fueron: T1) Dieta testigo, la cual contenía 0.33 mg de Se y T2) Testigo + 300 mg de Selplex, con una concentración final de 0.93 mg de Se. El ensayo se llevo a cabo usando 8 corderos con un peso inicial de 30.5 ± 2.09 Kg, donde la concentración de Se en tejidos, la actividad de glutatión peroxidasa y balance de Se fueron analizados. El Se en la dieta no afecto la concentración se esté en tejidos para el grupo testigo así como para los animales que recibieron Se orgánico. La actividad de glutatión peroxidasa no tuvo diferencias entre tratamientos, aunque presento una tendencia (p=0.0011) a disminuir...
Tipo: Tesis Palavras-chave: Selenio orgánico; Tejidos; Glutatión peroxidasa; Balance de selenio; Maestría; Ganadería; Organic selenium; Tissues; Glutathione peroxidase; Selenium balance.
Ano: 2009 URL: http://hdl.handle.net/10521/1236
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Suplemento de Selenio en la respuesta fisiológica en corderos Colegio de Postgraduados
López Gutiérrez, Artemisa Guadalupe.
Se llevó a cabo un ensayo para evaluar el efecto de la concentración de Selenio (Se) en la dieta, así como la adición de Se orgánico, los tratamientos fueron: T1) Dieta testigo, la cual contenía 0.33 mg de Se y T2) Testigo + 300 mg de Selplex, con una concentración final de 0.93 mg de Se. El ensayo se llevo a cabo usando 8 corderos con un peso inicial de 30.5 ± 2.09 Kg, donde la concentración de Se en tejidos, la actividad de glutatión peroxidasa y balance de Se fueron analizados. El Se en la dieta no afecto la concentración se esté en tejidos para el grupo testigo así como para los animales que recibieron Se orgánico. La actividad de glutatión peroxidasa no tuvo diferencias entre tratamientos, aunque presento una tendencia (p=0.0011) a disminuir...
Palavras-chave: Selenio orgánico; Tejidos; Glutatión peroxidasa; Balance de selenio organic selenium; Tissues; Glutathione peroxidase; Selenium balance.
Ano: 2012 URL: http://hdl.handle.net/10521/840
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Активность ферментов пероксидного комплекса тканей мидии Mytilus galloprovincialis Lam в норме и в условиях естественного окислительного стресса IBSS Repository
Гостюхина, О. Л.; Солдатов, А. А.; Головина, И. В..
Исследовано содержание продуктов перекисного окисления липидов (ПОЛ) и состояние ферментативного пероксидного комплекса (ПК) (глутатионпероксидазы (ГП), каталазы и пероксидазы) в гепатопанкреасе, жабрах и ноге черноморского моллюска Mytilus galloprovincialis Lam. в условиях физиологического покоя и нереста. Последнее рассматривали как модель естественного окислительного стресса. Изучали особей двух цветовых морф - черной и коричневой. Выявлена тканевая специфика активностей ферментов и распределения продуктов ПОЛ в состоянии нормы, а также особенности ответных реакций тканей моллюсков обеих морф при действии окислительной нагрузки. Наиболее чувствительной к действию перекисных продуктов в условиях естественного окислительного стресса оказались особи черной...
Tipo: Journal Contribution Palavras-chave: Ферменты; Каталаза; Пероксидаза; Глутатионпероксидаза; Перекисное окисление липидов; Окислительный стресс; Мидии; Цветовые морфы; Нерест; Enzymes; Catalase; Peroxidase; Glutathione peroxidase; Lipid peroxidation; Spawning; Oxidative stress; Mussels; Color morphs Spawning Enzymes Lipids Spawning Enzymes Lipids http://aims.fao.org/aos/agrovoc/c_14490 http://aims.fao.org/aos/agrovoc/c_2603 http://aims.fao.org/aos/agrovoc/c_4362.
Ano: 2005 URL: http://repository.ibss.org.ua/dspace/handle/99011/226
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