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Endotoxin inhibits the surge secretion of gonadotropin-releasing hormone via a prostaglandin-independent pathway Inra
Breen, K.M.; Billings, H. J.; Debus, N.; Karsch, F. J..
Immune/inflammatory challenges, such as bacterial endotoxin, disrupt gonadotropin secretion and ovarian cyclicity. We previously determined that endotoxin can block the estradiol-induced LH surge in the ewe. Here, we investigated mechanisms underlying this suppression. First, we tested the hypothesis that endotoxin blocks the estradiol-induced LH surge centrally, by preventing the GnRH surge. Artificial follicular phases were created in ovariectomized ewes, and either endotoxin or vehicle was administered together with a surge-inducing estradiol stimulus. In each ewe in which endotoxin blocked the LH surge, the GnRH surge was also blocked. Given this evidence that endotoxin blocks the estradiol-induced LH surge at the hypothalamic level, we began to assess...
Tipo: Journal Article Palavras-chave: ENDOTOXINE; HORMONE GONADOTROPE; GONADOTROPINE; PROSTAGLANDINE; SECRETION DE LH; PULSE DE GNRH; CYCLE OVARIEN; HYPOTHALAMUS ENDOTOXIN; HORMONE; GONADOTROPIN; GNRH; LH.
Ano: 2004 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2007a6a7a3a2&uri=/notices/prodinra1/2008/09/
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Quantity, motility and fertility of tench Tinca tinca (L.) sperm in relation to LHRH analogue and carp pituitary treatments Inra
Caille, N.; Rodina, M.; Kocour, M.; Gela, D.; Flajšhans, M.; Linhart, O..
The spermiation of tench males was stimulated with Supergestran containing mammalian LHRHa lecireline at the following doses: 5, 10, 20 and 40 μg kg−1 b.w.; then with carp pituitary suspension (CPS) at a dose of 2 mg kg−1 b.w. and with a control of saline physiological solution. The following days, meaning 24, 48 and 72 h after injection, sperm was collected to evaluate volume and the number of sperm per male per kg body weight (B.W.) The percentage of motile sperm and velocity of spermatozoa were measured 48 h after hormonal injection, and 72 h after hormonal injection the sperm was evaluated for fertilization and hatching ability. All 42 males in experimental groups were diploid. Live weight did not differ significantly among experimental groups. The...
Tipo: Conference Paper Palavras-chave: SPERME; SPERMATOZOIDE; SPERMIATION; NEUROHORMONE; LHRH; HYPOPHYSE; HORMONE GONADOTROPE; MOTILITE DU SPERME.
Ano: 2006 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2007d8bd4817&uri=/notices/prodinra1/2010/09/
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