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Ordenar por: RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 6
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Dynamics of immunosuppression in hamsters with experimental visceral leishmaniasis BJMBR
Fazzani,C.; Guedes,P.A.; Senna,A.; Souza,E.B.; Goto,H.; Lindoso,J.A.L..
Immunosuppression has been reported to occur during active visceral leishmaniasis and some factors such as the cytokine profile may be involved in this process. In the mouse model of cutaneous leishmaniasis using Leishmania (Leishmania) major, the Th1 response is related to protection while the Th2 response is related to disease progression. However, in hamsters, which are considered to be an excellent model for the study of visceral leishmaniasis, this dichotomy is not observed. Using outbred 45- to 60-day-old (140 to 150 g) male hamsters infected intraperitoneally with 2 x 10(7) L. (L.) chagasi amastigotes, we evaluated the immune response of spleen cells and the production of cytokines. We used 3 to 7 hamsters per group evaluated. We detected a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunosuppression; Leishmania(Leishmania) chagasi; Hamster; Cytokine; T-cell proliferation.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000700009
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Endocrine Integration of Fetal Ovaries Grafted under Kidney Capsule of Unilaterally or Bilaterally Orchidectomized Male Hamster International Journal of Morphology
Luna,S. L; Peña,S. I; Cuevas,A. J; Brown,D. I.
Mammalian ovary development undergoes important changes during the perinatal period, moment when follicles are assembled and start to develop in a process not well known, involving endocrine and paracrine factors. In order to investigate the effect of two different hormonal environments on the early development of the ovary, we used an autologous transplant model in which Syrian hamster fetal ovaries were grafted under the kidney capsule of males hosts previously unilaterally or bilaterally orchidectomized. After 35 days of graft, ovaries and kidney parenchyme of the host male did not present signs of rejection. Ovaries contained primordial, primary follicles, secondary follicles and few tertiary follicles with morphological features similar to ovaries of...
Tipo: Journal article Palavras-chave: Ovary; Folliculogenesis; Steroidogenesis; Ovarian graft; Hamster.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000400016
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Experimental chronic entrapment of the sciatic nerve in adult hamsters: an ultrastructural and morphometric study BJMBR
Prinz,R.A.D.; Nakamura-Pereira,M.; De-Ary-Pires,B.; Fernandes,D.S.; Fabião-Gomes,B.D.S.V.; Bunn,P.S.; Martinez,A.M.B.; Pires-Neto,M.A.; Ary-Pires,R..
Entrapment neuropathy is a group of clinical disorders involving compression of a peripheral nerve and interference with nerve function mostly through traction injury. We have investigated the chronic compression of peripheral nerves as an experimental procedure for detecting changes in ultrastructural nerve morphology. Adult hamsters (Mesocricetus auratus, N = 30) were anesthetized with a 25% pentobarbital solution and received a cuff around the right sciatic nerve. Left sciatic nerves were not operated (control group). Animals survived for varying times (up to 15 weeks), after which they were sacrificed and both sciatic nerves were immediately fixed with a paraformaldehyde solution. Experimental nerves were divided into segments based upon their distance...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Nerve entrapment; Ultrastructure; Morphometry; Hamster; Renaut body.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000900015
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Immunity and immunosuppression in experimental visceral leishmaniasis BJMBR
Goto,H.; Lindoso,J.A.L..
Leishmaniasis is a disease caused by protozoa of the genus Leishmania, and visceral leishmaniasis is a form in which the inner organs are affected. Since knowledge about immunity in experimental visceral leishmaniasis is poor, we present here a review on immunity and immunosuppression in experimental visceral leishmaniasis in mouse and hamster models. We show the complexity of the mechanisms involved and differences when compared with the cutaneous form of leishmaniasis. Resistance in visceral leishmaniasis involves both CD4+ and CD8+ T cells, and interleukin (IL)-2, interferon (IFN)- gamma, and IL-12, the latter in a mechanism independent of IFN- gamma and linked to transforming growth factor (TGF)-ß production. Susceptibility involves IL-10 but not IL-4,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Visceral leishmaniasis; Immunosuppression; T cell; Cytokines; Mice; Hamster.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000400020
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Localization of Total Proteins and Lactate Dehydrogenase in Hamster Epididymis International Journal of Morphology
Beu,Celia C. L.; Orsi,Antonio M; Domeniconi,Raquel F; Novelli,Ethel L. B..
The concentration of total protein measured by photocolorimetric methodology and reported as units per 100 mg of tissue decreased from the initial segment to the cauda epididymidis of the Golden hamster, being significant the numeric difference observed between these two regions. This observation was related with an increased synthesis and secretion of proteins to the lumen in proximal segments of the epididymidis duct, mainly in initial segment, as proposed for other rodents. LDH activity was higher in initial segment and distal cauda than in the caput and corpus epididymidis, although no significant differences in mean values had been observed. The high LDH activity observed in initial segment and cauda epididymidis of hamster had been related to an...
Tipo: Journal article Palavras-chave: Total protein; LDH; Tissue localization; Epididymis; Hamster.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200003
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Pathogenesis of rabies virus by ERA and PV strains administered orally in hamsters (M. auratus) Braz. J. Vet. Res. Anim. Sci.
Alves,Luciane Martins; Soares,Rodrigo Martins; Cortez,Adriana; Richtzenhain,Leonardo José; Ito,Fumio Nonma.
Hamsters orally inoculated with ERA and PV strains of rabies virus were sacrificed at 24, 48, 72 hours, 21 and 30 days after inoculation. Brain fragments were examined by Fluorescent Antibody test (FAT) and heminested PCR (hn-PCR). Fragments from stomach, blood, heart, and lung were examined only by hn-PCR. Sera of other hamsters, similarly inoculated, obtained at 30th day after inoculation were submitted to mouse neutralization test. The hamsters were challenged intracerebrally with CVS strain with 10(2.7)mouse LD50/0.03mL, 45 days after inoculation. Brains examined by FAT were negative. The hn-PCR detected the presence of rabies virus RNA in the lung of one animal inoculated with ERA, and in the brain, stomach, blood, and lung of PV-infected animals. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rabies; Oral administration; ERA and PV strains; Hn-PCR; Hamster.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962003000100010
Registros recuperados: 6
Primeira ... 1 ... Última
 

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