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Registros recuperados: 3
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Altered Liver Morphology and Enzymes in Streptozotocin Induced Diabetic Rats International Journal of Morphology
Zafar,Muhammad; Naeem-ul-Hassan Naqvi,Syed; Ahmed,Masood; Kaimkhani,Zahid Ali.
This study was undertaken to evaluate the relationship and effects of diabetes on liver morphology, architecture and function. The hepatic effects of diabetes were evaluated in vivo using streptozotocin (STZ)-induced diabetic rats as an experimental model. The degree of hepatic dysfunction was measured by using biochemical parameters like serum transaminases (ALT and AST), alkaline phosphatase (ALP)and pseudocholinesterase (PChE) while the histopathological studies were carried out to support the enzymic Parameters. The aim of the study was to investigate the association between diabetic hepatic complications and liver enzyme alterations. This study was performed in the Department of Anatomy; Institute of Pharmaceutical Sciences and Institute of...
Tipo: Journal article Palavras-chave: Streptozotocin; Aminotransferases; Alkaline phosphatase; Pseudocholinesterase; STZ-diabetes; Hepatic injury.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300015
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Aminotransferase changes and acute hepatitis in patients with dengue fever: analysis of 1,585 cases BJID
Souza,Luiz José de; Alves,José Galvão; Nogueira,Rita Maria Ribeiro; Gicovate Neto,Carlos; Bastos,Diogo Assed; Siqueira,Edno Wallace da Silva; Souto Filho,João Tadeu Damian; Cezário,Thiago de Abreu; Soares,Carlos Eduardo; Carneiro,Rodrigo da Costa.
INTRODUCTION: Type 3 dengue virus caused an extensive epidemic in the state of Rio de Janeiro in summer 2002. In some of the patients, it was found in an atypical form with increased aminotransferase levels and acute hepatitis. MATERIAL AND METHODS: An analysis was made of 1,585 serologically confirmed dengue cases at the Dengue Reference Center in Campos dos Goytacazes, Rio de Janeiro state. The grade of hepatic aggression was established according to the alterations in the aminotransferase levels: grade A - normal levels of aminotransferase; grade B - elevated aminotransferase, with increased levels of at least one of the enzymes; grade C - elevated aminotransferase, with the levels of at least one of the enzymes increased to more than three times the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dengue fever; Aminotransferase; Hepatic injury.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000200006
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Effects of perinatal exposure to nonylphenol on delivery outcomes of pregnant rats and inflammatory hepatic injury in newborn rats BJMBR
Yu,J.; Luo,Y.; Yang,X.F.; Yang,M.X.; Yang,J.; Yang,X.S.; Zhou,J.; Gao,F.; He,L.T.; Xu,J..
The current study aimed to investigate the effects of perinatal exposure to nonylphenol (NP) on delivery outcome of pregnant rats and subsequent inflammatory hepatic injury in newborn rats. The pregnant rats were divided into 2 groups: control group (corn oil) and NP exposure group. Thirty-four pregnant rats were administered NP or corn oil by gavage from the sixth day of pregnancy to 21 days postpartum, with blood samples collected at 12 and 21 days of pregnancy and 60 days after delivery. The NP concentration was measured by HPLC, with chemiluminescence used for detection of estrogen and progesterone levels. Maternal delivery parameters were also observed. Liver and blood of the newborn rats were collected and subjected to automatic biochemical detection...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nonylphenol; Hepatic injury; Delivery; Newborn rats.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016001200702
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