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Acute inflammatory response in Nile tilapia fed probiotic Lactobacillus plantarum in the diet - doi: 10.4025/actascibiolsci.v33i3.8011 Biological Sciences
Dotta, Geovana; Laboratório AQUOS-Sanidade de Organismos Aquáticos, Depto. de Aqüicultura, CCA, UFSC - Rod. Admar Gozaga 1346 - 88040-900 - Florianópolis, SC - Brasil; Mouriño, José Luis Pedreira; Laboratório de Camarões Marinhos, Depto. de Aqüicultura, CCA, UFSC, Beco dos Coroas, Barra da Lagoa - Florianópolis, SC - Brasil; Jatobá, Adolfo; Laboratório de Camarões Marinhos, Depto. de Aqüicultura, CCA, UFSC, Beco dos Coroas, Barra da Lagoa - Florianópolis, SC - Brasil; Burgos Morán, Ricardo Ernesto; Universidad Politécnica de Catalunya, Campus del Baix Llobregat, Av. del Canal Olímpic, s/n - 08860 - Castelldefels, Catalunya - España; Pilati, Celso; UFSC; Martins, Maurício Laterça; UFSC.
The present study evaluated the acute inflammatory response induced by carrageenin (500 µg) injected in the swim bladder of Nile tilapia, after fed or not probiotic supplemented diet. Fifty four fish were distributed in six treatments and three replicates: Group A: Fish fed unsupplemented diet: 0.5 mL saline-injected fish; fish injected with 500 µg carrageenin diluted in 0.5 mL saline; Non-injected. Group B: Fish fed probiotic supplemented diet: saline-injected fish; carrageenin-injected fish; Non-injected. Fifteen days after feeding the fish were injected with carrageenin or saline. After six hours, inflammatory exudate was collected, as well as the blood for hematocrit, red blood cell (RBC) and white blood cell (WBC) counts,...
Tipo: Composição bioquímica Palavras-chave: 2.00.00.00-6 Ciencias Biologicas Tilapia; Probiotic; Lactobacillus plantarum; Inflammation; Haematology; Phagocytosis 2.00.00.00-6 Ciencias Biologicas Tilapia; Probiotic; Lactobacillus plantarum; Inflammation; Haematology; Phagocytosis.
Ano: 2011 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/8011
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ACUTE-PHASE REACTIONS, INCLUDING CYTOKINES, IN PATIENTS BITTEN BY BOTHROPS AND CROTALUS SNAKES IN BRAZIL J. Venom. Anim. Toxins
BARRAVIERA,B.; LOMONTE,B.; TARKOWSKI,A.; HANSON,L. Å.; MEIRA,D.A..
Thirty-one patients bitten by venomous snakes in Botucatu area (State of São Paulo - Brazil), sixteen by Bothrops spp. and fifteen by Crotalus durissus terrificus, were studied. The group comprised twenty-nine males and two females, ranging from fourteen to sixty-three years of age (mean 33 ± 15). Leukocytosis with neutrophilia and lymphopenia, increase of mucoproteins and C-reactive protein, decrease of total serum protein and albumin, were observed on the first day after the accident. In addition, increased serum levels of the cytokines IL-6 and IL-8, but not of IL-1<FONT FACE="Symbol">b</FONT> and TNF-<FONT FACE="Symbol">a</FONT>, were observed. The alterations were generally more intense in patients bitten by Crotalus durissus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Snake venom; Acute-phase reactions; Cytokines; C-reactive protein; Inflammation.
Ano: 1995 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301995000100003
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Aneurisma na artéria aorta em caprinos. Repositório Alice
SANTA ROSA, J.; BERNE, M. E. A.; JOHNSON, E. H..
Resumo: De 726 caprinos necropsiados, dois (0,28%) apresentaram aneurisma na arteria aorta, sendo um macho com idade de 48 meses e uma femea com cerca de 30 meses. Os animais eram oriundos de um rebanho mantido em regime semi-extensivo com pastejo em caatinga nativa e pernoite em aprisco. Macroscopicamente observou-se palidez das mucosas externas e das visceras. Nas cavidades toracica e abdominal estavam presentes grandes coagulos resultantes da ruptura das partes afetadas das arterias. As lesoes das arterias aorta toracica e abdominal foram carcterizadas pela dilatacao das paredes formando estruturas saculares com presenca de inumeros coagulos e tecidos necroticos de aproximadamente 10cm a 20cm de comprimento. Histologicamente, observou-se a destruicao do...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Aneurisma; Arteria aorta; Ectasia; Caprino; Doença vascular; Artéria; Inflamação; Arteritis; Aneurysm; Vascular diseases; Goats; Animal diseases; Inflammation.
Ano: 1989 URL: http://www.alice.cnptia.embrapa.br/handle/doc/514186
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Anti-inflammatory Effect of Silymarin on Ovarian Immunohistochemical Localization of TNF- Associated with Systemic Inflammation in Polycystic Ovarian Syndrome International Journal of Morphology
Kayedpoor,Parvin; Mohamadi,Shima; Karimzadeh-Bardei,Latifeh; Nabiuni,Mohammad.
Tumor necrosis factor alpha (TNF-a) and interleukin (IL)-6, are prominent mediators of inflammation and have been confirmed to be elevated in at least a subgroup of women with polycystic ovary syndrome (PCOS). In this study, the effects of Silymarin (SLM) on the expression TNF-a, IL-6, CRP and symptoms of PCOS were studied. In this research, PCOS was induced by injection of Estradiol Valerate. PCOS rats were divided into control and experimental groups received intraperitoneal injection SLM extract daily. After syndrome induction, ovaries were collected for histological and immunohistochemical evaluations. Serum IL-6 was detected by the ELISA kit. The results indicated the significant reduction in inflammatory markers and significant changes follicular...
Tipo: Journal article Palavras-chave: Immunohistochemistry; Inflammation; Silybum Marianum extract.
Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200054
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Anti-inflammatory potential of 2-styrylchromones regarding their interference with arachidonic acid metabolic pathways IPB - Escola Superior Agrária
Gomes, Ana; Fernandes, Eduarda; Silva, Artur; Pinto, Diana; Santos, Clementina M.M.; Cavaleiro, José; Lima, José Costa.
Cyclooxygenases (COXs) are the key enzymes in the biosynthesis of prostanoids. COX-1 is a constitutive enzyme while the expression of COX-2 is highly stimulated in the event of inflammatory processes, leading to the production of large amounts of prostaglandins (PGs), in particular PGE2 and PGI2, which are pro-inflammatory mediators. Lipoxygenases (LOXs) are enzymes that produce hydroxy acids and leukotrienes (LTs). 5-LOX metabolizes arachidonic acid to yield, among other products, LTB4, a potent chemoattractantmediator of inflammation. The aim of the present work was to evaluate the anti-inflammatory potential of 2-styrylchromones (2-SC), a chemical family of oxygen heterocyclic compounds, vinylogues of flavones (2-phenylchromones), by studying their...
Tipo: Article Palavras-chave: 2-Styrylchromones; Cyclooxygenase; 5-Lipoxigenase; Leukotriene B4; Dual inhibitors; Inflammation.
Ano: 2009 URL: http://hdl.handle.net/10198/3919
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ANTITUMOR EFFECT OF SNAKE VENOMS J. Venom. Anim. Toxins
SILVA,R. J. DA; FECCHIO,D.; BARRAVIERA,B..
The search for biological antitumor agents has been pursued for over half a century. Snake venom has been shown to possess a wide spectrum of biological activities. The objectives of the present review are to evaluate the existing controversies on this subject published in a number of papers and to propose probable explanations for the phenomena observed. We reported our results obtained in a study, in which we evaluated the action of the venoms of Crotalus durissus terrificus and Bothrops jararaca on Ehrlich ascites tumor cells. We noticed an important antitumor effect, mainly with Bothrops jararaca venom, as well as an increase in the functional activity of macrophages. We also observed an increase in the number of mononuclear and polymorphonuclear cells...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cancer; Inflammation; Venom; Snakes; Crotalus durissus terrificus; Bothrops jararaca.
Ano: 1996 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301996000200002
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EFFECT OF Crotalus durissus terrificus (LAURENTI, 1768) VENOM ON THE EVOLUTION OF EHRLICH ASCITES TUMOR J. Venom. Anim. Toxins
SILVA,R. J. DA; FECCHIO,D.; BARRAVIERA,B..
The effect of Crotalus durissus terrificus (LAURENTI, 1768) venom on the evolution of Ehrlich ascites tumor cells was evaluated. Thus, 30-day-old male mice of the Swiss strain were inoculated intraperitoneally with 1x10<img SRC="http:/img/fbpe/jvat/v3n2/image1947.gif"> tumor cells. Then, 7 groups of animals were formed: 3 control groups (physiological, venom and tumor) and 4 experimental groups that received different doses of venom. The experimental groups received 5 intraperitoneal venom injections on the 1<img SRC="http:/img/fbpe/jvat/v3n2/image1948.gif"> , 4<img SRC="http:/img/fbpe/jvat/v3n2/image1949.gif"> , 7<img SRC="http:/img/fbpe/jvat/v3n2/image1949.gif"> , 10<img SRC="http:/img/fbpe/jvat/v3n2/image1949.gif"> and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Venom; Inflammation; Tumor growth; Crotalus durissus terrificus.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000200008
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Effects of Fetal Programming in the Inflammatory Response in Wistar Rats: A Systematic Review International Journal of Morphology
Assis,Thiago de Oliveira; Araújo Filho,José Candido de; Maia,Maria Bernadete de Sousa.
The aim of this study was to review the literature on the effects of fetal programming in the inflammatory response in Wistar rats. A search was performed in the following databases: PubMed, MEDLINE, PUBMED, SCIENCE DIRECT, SCOPUS, LILACS, SpringerLink. The main search terms were malnutrition and inflammation in Portuguese and in English. Original articles were included involving albino rats and review articles were excluded involving humans or animals other than rats. Articles that were related to malnutrition which was not intrauterine and did not involve the concept of fetal programming were also excluded.Those items found in more than one database were counted only once. Sixteen articles were found in PUBMED, 16 in SCOPUS, 4 in MEDLINE, 341 in SCIENCE...
Tipo: Journal article Palavras-chave: Fetal Programming; Inflammation; Wistar Rats; Systematic review.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400048
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Effects of tea on survival rates and liver pathology of Trypanosoma brucei brucei infected mice OAK
Mbuthia, S.K; Wachira, N.W; Ngure, R.M; Ouma, J; Kagira, J.M.
The current study investigated the effects of different types of Kenyan tea extracts on the pathogenesis of Trypanosoma brucei brucei in a Swiss White mice model. Following infection with trypanosomes, the mice were monitored for survival and liver pathology. Tea significantly (P<0.05) enhanced the survival rate of tea treated mice. Additionally, in tea treated but infected mice, there was reduction in infiltration of inflammatory cells into the periportal and parenchymal regions as well as hepatocyte cell damage compared to the infected untreated animals. Green and white teas were superior in most of the above effects while black tea and oolong teas had the least effects. The tea extracts were more efficacious than dexamethasone in prolonging the life...
Palavras-chave: Inflammation; Liver pathology; Survival rate; Tea; Trypanosomiasis.
Ano: 2011 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3094
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Evaluation of the health benefits of consumption of extruded tannin sorghum with unfermented probiotic milk in individuals with chronic kidney disease. Repositório Alice
LOPES, R. de C. S. O.; LIMA, S. L. L. de; SILVA, B. F. da; TOLEDO, R. C. L.; MOREIRA, M. E de C.; ANUNCIAÇÃO, P. C. de; WALTER, E. H. M.; CARVALHO, C. W. P. de; QUEIROZ, V. A. V.; RIBEIRO, A. Q.; MARTINO, H. S. D..
This study investigated the chemical and nutritional composition of breakfast cereal based on whole sorghum, and the effect of its association with unfermented probiotic milk on the inflammation and oxidative stress of individuals with chronic kidney disease. Extruded sorghum breakfast meal presented higher carbohydrate concentration (approximately 71%), followed by protein (approximately 11%) and lipid (approximately 0.4%). When compared to extruded maize breakfast meal, it presented higher percentage of dietary fiber (p < 0.05), and higher content of phenolic compounds and tannin, consequently higher antioxidant activity (p < 0.05). Extruded sorghum breakfast cereal combined with unfermented probiotic milk decreased the C-reactive protein (p <...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Tecnologia de Alimento; Composto Fenólico; Fibra; Dieta; Antioxidante; Doença; Extrusão; Fermentação; Sorgo; Tanino; Leite de Soja; Cereal; Rim; Inflamação; Sorghum Bicolor; Phenolic compounds; Dietary fiber; Antioxidants; Chronic diseases; Probiotics; Food technology; Tannins; Milk analysis; Breakfast cereals; Antioxidant activity; Inflammation; Kidney diseases.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1091120
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Evaluation of the health benefits of consumption of extruded tannin sorghum with unfermented probiotic milk in individuals with chronic kidney disease. Repositório Alice
LOPES, R. de C. S. O.; LIMA, S. L. L. de; SILVA, B. F. da; TOLEDO, R. C. L.; MOREIRA, M. E de C.; ANUNCIAÇÃO, P. C. de; WALTER, E. H. M.; CARVALHO, C. W. P. de; QUEIROZ, V. A. V.; RIBEIRO, A. Q.; MARTINO, H. S. D..
This study investigated the chemical and nutritional composition of breakfast cereal based on whole sorghum, and the effect of its association with unfermented probiotic milk on the inflammation and oxidative stress of individuals with chronic kidney disease. Extruded sorghum breakfast meal presented higher carbohydrate concentration (approximately 71%), followed by protein (approximately 11%) and lipid (approximately 0.4%). When compared to extruded maize breakfast meal, it presented higher percentage of dietary fiber (p < 0.05), and higher content of phenolic compounds and tannin, consequently higher antioxidant activity (p < 0.05). Extruded sorghum breakfast cereal combined with unfermented probiotic milk decreased the C-reactive protein (p <...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Tecnologia de Alimento; Composto Fenólico; Fibra; Dieta; Antioxidante; Doença; Extrusão; Fermentação; Sorgo; Tanino; Leite de Soja; Cereal; Rim; Inflamação; Sorghum Bicolor; Phenolic compounds; Dietary fiber; Antioxidants; Chronic diseases; Probiotics; Food technology; Tannins; Milk analysis; Breakfast cereals; Antioxidant activity; Inflammation; Kidney diseases.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1091257
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FISH IMMUNE SYSTEM Gayana
Olabuenaga,Susana E..
The defence against infections is the essential function of the immune system of all Vertebrates. Fish present an efficient and developed immunologic response and in the case of Teleosts, with some similarities to the higher vertebrates. It can be divided into two types: innate or non specific and adquired or specific, both with a humoral and cellular compartments. Their relative importance can change according to the age of fish and is always under the influence of different factors. The most relevant components are mentioned here. There are two factors in fishes which strongly influence the immune response and antibody production, seasonal changes and temperature. The main lymphoid organs are described here: the thymus, the kidney and the spleen, as well...
Tipo: Journal article Palavras-chave: Antigen; Antibody; Leukocytes; Phagocytosis; Lymphokines; Inflammation; Immunostimulants.
Ano: 2000 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-65382000000200010
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Fractal Analysis of Skeletal Muscle Tissue of Rats Subjected to Stretch Injury International Journal of Morphology
Ozaki,Guilherme; Camargo,Regina Celi Trindade; Koike,Tatiana Emy; Garcia,Thiago Alves; Castoldi,Robson Chacon; Camargo Filho,Jose Carlos Silva.
The aim of this study was to analyze changes in the skeletal muscle tissue of rats after muscle stretch injury using fractal analysis. Nineteen rats were divided into three groups, Control (n= 5) (C), Lesion two days (n= 7) (L2), and Lesion seven days (n= 7) (L7). Histological slides of the gastrocnemius muscle of the animals were prepared and stained with Hematoxylin and eosin for analysis of the inflammatory process, and picrosirius for the demonstration of collagen. The stained slides were subsequently analyzed using Fractal Dimension (FD). The results showed high FD values of the inflammatory process in the experimental groups L2 and L7 in relation to C (p= 0.000). The analysis of collagen in the picrosirius stained slides showed high FD in the L2...
Tipo: Journal article Palavras-chave: Fractal analysis; Skeletal muscle injury; Collagen; Inflammation; Pathology.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300017
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Histological Changes Implicated in Metastasis International Journal of Morphology
Díaz-Peña,Roberto; Castro-Santos,Patricia.
The process of malignancy emergence is associated with the acquisition of the capacity to invade other tissues. Several different biological processes have been described as involved in this process. Specifically, epithelial mesenchymal transition (EMT), a mechanism associated with embryogenesis and wound repair but also with mobility acquisition, is one of the concerned processes. In EMT an epithelial cell loses its epithelial characteristics, its junctions with neighbor cells and with the basal lamina and acquires mobility and mesenchymal characteristics. Also, factors of the tumor microenvironment have been described as involved. Tumor presence triggers a response in the surrounding tissue known as reactive stromal. It shows particular characteristics...
Tipo: Journal article Palavras-chave: EMT; CAF; Metastasis; Cancer; Inflammation.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300031
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Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids BJMBR
Calder,P.C..
1. Fish oils are rich in the long-chain n-3 polyunsaturated fatty acids (PUFAs), eicosapentaenoic (20:5n-3) and docosahexaenoic (22:6n-3) acids. Linseed oil and green plant tissues are rich in the precursor fatty acid, <FONT FACE="Symbol">a</font>-linolenic acid (18:3n-3). Most vegetable oils are rich in the n-6 PUFA linoleic acid (18:2n-6), the precursor of arachidonic acid (20:4n-6). 2. Arachidonic acid-derived eicosanoids such as prostaglandin E2 are pro-inflammatory and regulate the functions of cells of the immune system. Consumption of fish oils leads to replacement of arachidonic acid in cell membranes by eicosapentaenoic acid. This changes the amount and alters the balance of eicosanoids produced. 3. Consumption of fish oils diminishes...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lymphocyte; Macrophage; Immune system; Inflammation; Fish oil; Polyunsaturated fatty acid; Cytokine; Eicosanoid.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000400002
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In vivo and in vitro anti-inflammatory activity of Cryptostegia grandiflora Roxb. ex R. Br. leaves Biol. Res.
Castro,Jenny P; Ocampo,Yanet C; Franco,Luis A.
BACKGROUND: Despite Cryptostegia grandiflora Roxb. ex R. Br. (Apocynaceae) leaves are widely used in folk Caribbean Colombian medicine for their anti-inflammatory effects, there are no studies that support this traditional use. Therefore, this work aimed to evaluate the effect of the total extract and primary fractions obtained from Cryptostegia grandiflora leaves, using in vivo and in vitromodels of inflammation, and further get new insights on the mechanisms involved in this activity. RESULTS: Ethanolic extract of Cryptostegia grandiflora leaves, and its corresponding ether and dichloromethane fractions, significantly reduced inflammation and myeloperoxidase activity (MPO) in ear tissue of mice treated with 12-O-tetradecanoyl-phorbol-13-acetate (TPA)....
Tipo: Journal article Palavras-chave: Ear edema; Free radicals; Inflammation; MPO; PGE2; RAW 264; 7 macrophages.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100032
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Inflammatory and anti-inflammatory effects of soybean agglutinin BJMBR
Soybean agglutinin (SBA) lectin, a protein present in raw soybean meals, can bind to and be extensively endocytosed by intestinal epithelial cells, being nutritionally toxic for most animals. In the present study we show that SBA (5-200 µg/cavity) injected into different cavities of rats induced a typical inflammatory response characterized by dose-dependent exudation and neutrophil migration 4 h after injection. This effect was blocked by pretreatment with glucocorticoid (0.5 mg/kg) or by co-injection of N-acetyl-galactosamine (100 x [M] lectin), but not of other sugars (100 x [M] lectin), suggesting an inflammatory response related to the lectin activity. Neutrophil accumulation was not dependent on a direct effect of SBA on the macrophage population...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Lectin; Soybean agglutinin (SBA); Neutrophil migration; Inflammation.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000700009
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Influence of low environmental temperature on inflammation in bullfrog (Rana catesbeiana): qualitative and quantitative evaluation Braz. J. Vet. Res. Anim. Sci.
CATÃO-DIAS,José Luiz; SINHORINI,Idércio Luiz.
Objectives of this study were to investigate the influence of low environmental temperature on the experimentally induced inflammatory response in post-metamorphic Rana catesbeiana (bullfrogs). To accomplish these goals, 120 specimens of Rana catesbeiana were kept at 6ºC and 24ºC, and treated by transfixion of thigh muscular tissue with a 5-0 suture or IM carrageenan injection. Results obtained through qualitative and quantitative evaluations showed that the lower environmental temperature significantly modulates the inflammatory process development. The animals in both models that were kept at 6ºC showed a significantly lower number of inflammatory cells in the lesion site than the one verified at 24ºC, apart from the evolution time. On the other hand,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Inflammation; Temperature; Amphibia; Rana catesbeiana; Bullfrog.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95961999000200004
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Metabotropic glutamate receptor 5 may be involved in macrophage plasticity Biol. Res.
Shanshiashvili,Lali; Tsitsilashvili,Elene; Dabrundashvili,Nino; Kalandadze,Irine; Mikeladze,David.
Abstract Background Macrophages are a functionally heterogeneous cell population and depending on microenvironments they polarize in two main groups: M1 and M2. Glutamic acid and glutamate receptors may participate in the regulation of macrophage plasticity. To investigate the role of glutamatergic systems in macrophages physiology, we performed the transfection of mGluR5 cDNAs into RAW-264.7 cells. Results Comparative analysis of modified (RAW-mGluR5 macrophages) and non-modified macrophages (RAW-macrophages) has shown that the RAW-mGluR5 macrophages absorbed more glutamate than control cells and the amount of intracellular glutamate correlated with the expression of excitatory amino acid transporters -2 (EAAT-2). Besides, our results have shown that...
Tipo: Journal article Palavras-chave: Macrophages; Metabotropic glutamate receptors; Inflammation; HMGB1; IL-10.
Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100203
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Preventive effect of Ligularia fischeri on inhibition of nitric oxide in lipopolysaccharide-stimulated RAW 264.7 macrophages depending on cooking method Biol. Res.
Park,Hee-Sook; Choi,Hye-Young; Kim,Gun-Hee.
BACKGROUND: Ligularia fischeri (common name Gomchwi) is known for its pharmaceutical properties and used in the treatment of jaundice, scarlet-fever, rheumatoidal arthritis, and hepatic diseases; however, little is known about its anti-inflammatory effect. In this study the influence of blanching and pan-frying on the anti-inflammatory activity of Ligularia fischeri (LF) was evaluated. RESULTS: Fresh LF and cooked LF showed no significant effect on the viability of macrophages after 24 h incubation. Fresh LF was found to be the most potent inhibitor of nitric oxide (NO) production at 100 &#956;g/ml, while pan-fried LF showed little inhibitory effect on lipoloysaccharide (LPS) stimulated murine machrophage RAW264.7 cells. In contrast with its effect on...
Tipo: Journal article Palavras-chave: Chlorogenic acid; Inflammation; Ligularia fischeri; Macrophage.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100063
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