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A Rare Variation of the Retro-Aortic Left Renal Vein with Anastomotic Afluent from Inferior Mesenteric Vein International Journal of Morphology
Andrade,F. M.; Rocha,R. P.; Pereira,H. M.; Fernandes,R. M. P.; Babinski,M. A..
We report an uncommon anatomical variations of the left renal vein was found on dissected specimen in an elderly male cadaver: a retroaortic left renal vein. No other vascular anomalies were noted in this specimen. The anomaly result may be related to a particular pattern of left inferior vena cava. The abnormality have to be known for it may be undetected or be misleading in imaging. This anatomical curiosity should be kept in mind by clinicians and academics that may manipulate this anatomical area
Tipo: Journal article Palavras-chave: Anatomy; Anomalies; Kidney; Retroaortic renal vein.
Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000100001
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Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate International Journal of Morphology
Bomfim,Kátia Michelle dos Anjos; Garcia,Carlos Alexandre Borges; Reis,Francisco Prado; Palmeira,José Arnaldo Vasconcelos; Scher,Ricardo; de Lucca Júnior,Waldecy; Aragão,José Adeval; Vasconcelos,Francis Lima; Albuquerque Júnior,Ricardo Luiz Cavalcanti; Feitosa,Vera Lúcia Corrêa.
Lead is one of the heavy metals most used in industry. Poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has been known for many years. Lead is highly toxic and can compromise the structural and functional patterns of organs and systems. The aim of this study was to examine the lungs and kidneys of fetuses from female Wistar rats exposed to lead acetate. In this study, the lungs and kidneys of 20 fetuses from female rats that had previously been treated with lead acetate were dissected, fixed, embedded in paraffin and stained with hematoxylin and eosin. Macroscopic changes to the shape, color and consistency of organs from fetuses treated with this heavy metal were observed, in comparison with organs from...
Tipo: Journal article Palavras-chave: Lead acetate; Fetuses; Lung; Kidney.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100021
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Action of cobra venom on the renal cortical tissues: electron microscopic studies J. Venom. Anim. Toxins
RAHMY,T. R..
The effect of intramuscular (IM) injection of a sub-lethal dose of Naja haje cobra venom (0.015 mug/gm body weight) on the ultrastructure of renal cortical tissues of rabbits was studied at different time intervals after envenomation. Succinic dehydrogenase (SDH) enzyme activity was also detected in the renal cortical tubules. Three hours after venom injection, slight changes were seen in visceral cells and glomerular endothelia. The cortical tubular epithelia revealed an increase of lysosomal structures, cytoplasmic vacuolization, and nuclear irregularity. Severe ultrastructural changes were recorded 6 hours after envenomation, including hypertrophied parietal cells, blebbed visceral epithelial cells, and foot process disorganization. Dilated glomerular...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Snake venom; Nephrotoxicity; Kidney; Ultrastructure.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302001000100007
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Actions of Crotalus durissus terrificus venom and crotoxin on the isolated rat kidney BJMBR
Monteiro,H.S.A.; Silva,I.M.S.C. da; Martins,A.M.C.; Fonteles,M.C..
Many studies have reported the occurrence of lethal acute renal failure after snakebites. The aim of the present investigation was to determine alterations in renal function produced by Crotalus durissus terrificus venom and crotoxin as well as the histological alterations induced by these venoms. Isolated kidneys from Wistar rats weighing 240 to 280 g were perfused with Krebs-Henseleit solution containing 6 g% of previously dialyzed bovine serum albumin. The effects of Crotalus durissus terrificus venom and crotoxin were studied on glomerular filtration rate (GFR), urinary flow (UF), perfusion pressure (PP) and percentage sodium tubular transport (%TNa+). The infusion of Crotalus durissus terrificus venom (10 µg/ml) and crotoxin (10 µg/ml) increased GFR...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Crotalus durissus terrificus venom; Crotoxin; Kidney.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000017
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Alkaline phosphatase activity in plasma and liver of rats submitted to chronic exposure to fluoride BABT
Fernandes,Mileni da Silva; Iano,Flávia Godoy; Rocia,Vivian; Yanai,Marcela Mitsuko; Leite,Aline de Lima; Furlani,Tatiana Almeida; Buzalaf,Marília Afonso Rabelo; Oliveira,Rodrigo Cardoso de.
The aim of this study was to compare the effect of fluoride (F) on alkaline phosphatase activity in the liver and plasma of the rats. Four groups of male Wistar rats (n=6), which received drinking water containing 5, 15 or 50 ppm F or deionized water (control) throughout the experiment were included in the study. The animals were euthanized and had their tissues and blood plasma collected for the analysis of fluoride and alkaline phosphatase. There was an increase in F concentration in most tissues in the animals treated with higher F concentrations, except for the heart. The alkaline phosphatase assay showed an increase in the activity in the liver and blood plasma of the animals treated with fluoride concentrations of 15 and 50 ppm (p<0.05). This...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Alkaline phosphatase; Fluoride; Liver; Kidney.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600014
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Alpinia oxyphylla Miq. extract changes miRNA expression profiles in db-/db- mouse kidney Biol. Res.
Du,Guankui; Xiao,Man; Zhang,Xuezi; Wen,Maoyu; Pang,Chi; Jiang,Shangfei; Sang,Shenggang; Xie,Yiqiang.
Abstract Background A number of dysregulated miRNAs have been identified and are proposed to have significant roles in the pathogenesis of type 2 diabetes mellitus or renal pathology. Alpinia oxyphylla has shown significant anti-inflammatory properties and play an anti-diabetes role. The objective of this study was to detect the alteration of miRNAs underlying the anti-diabetes effects of A. oxyphylla extract (AOE) in a type II diabetic animal model (C57BIKsj db-/db-). Results Treatment with AOE for 8 weeks led to lower concentrations of blood glucose, urine albumin, and urine creatinine. 17 and 13 miRNAs were statistically identified as differentially regulated in the DB/DB and db-/db- AOE mice, respectively, compared to the untreated db-/db- mice. Of...
Tipo: Journal article Palavras-chave: MiRNA; Db-/db- mice; Alpinia oxyphylla Miq; Kidney; Diabetic nephropathy.
Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100206
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Alterações renais funcionais em caprinos submetidos a infusão intravenosa de hemolisado. Repositório Alice
PINHEIRO, R. R.; HAGIWARA, M. K.; KOGIKA, M. M.; BENESI, F. J..
Resumo: 0 presente estudo foi realizado em 32 caprinos, adultos, Sem Raça Definida (SRD), sendo 16 machos e 16 fêmeas, com propósito de constatar a existência de alteraçoes funcionais renais em caprinos submetidos à aplicaçào intravenosa de hemolisado, através de quantificação dos níveis séricos de uréia e creatinina. Constituiram-se 4 grupos, cada um composto de 8 animais, dos quais 5 foram submetidos a infusao de hemolisado e 3 permaneceram como controle. Nos animais os grupos l, II e III retiraram-se volumes sangüíneos respectivamente a 5, 10 e 15 ml/kg de peso corpóreo. Cada animal do grupo hemólise recebeu, por via intravenosa lenta, após ruptura mecânica das hemacias por congelamento, o hemolisado em igual volume ao sangue retirado. Os animais...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Níveis séricos; Biouímica sérica; Kidney; Serum level; Caprino; Rim; Ureia; Creatinina; Goats; Urea; Creatinine; Kidneys.
Ano: 1990 URL: http://www.alice.cnptia.embrapa.br/handle/doc/514137
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Anatomo-pathological and epidemiological analysis of urinary tract lesions in dogs Ciência Rural
Sapin,Carolina da Fonseca; Silva-Mariano,Luisa Cerqueira; Bassi,Jordana Nunes; Grecco,Fabiane Borelli.
ABSTRACT: In dogs, diseases of the urinary tract are common and can be caused by disorders of varied etiology. The objective of this study was to classify qualitatively and quantitatively urinary tract lesions of 363 dogs, which were classified according to its anatomical distribution and etiology. The data was obtained from the revision of 36 years of protocols from the Regional Laboratory of Diagnosis (LRD/UFPel) and it represents 4.0% of diagnoses from a total of 8980 for that period and species. Renal injury accounted for 93.1% of cases, with 309 being primary kidney lesions; from which the main lesions were the tubulointerstitial nephritis (142 cases) often associated with Leptospirosis (47). Injuries of lower urinary tract accounted for 6.9% of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dogs; Urinary tract; Kidney; Nefritis.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000801443
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Antivenom action on renal effects induced by Thalassophryne nattereri venom J. Venom. Anim. Toxins incl. Trop. Dis.
Martins,AMC; Barbosa,PSF; Sousa,DF; Alves,CD; Menezes,DB; Lima,C; Lopes-Ferreira,M; Fonteles,MC; Monteiro,HSA.
Thalassophryne nattereri (niquim) is a venomous fish responsible for numerous accidents involving fishermen in northern and northeastern Brazil. The aim of the present investigation was to evaluate the action of antivenom on renal effects caused by Thalassophryne nattereri venom. Isolated kidneys of Wistar rats were perfused with a previously dialyzed Krebs-Henseleit solution containing 6 g% bovine serum albumin. The antivenom action was studied through perfusion pressure (PP), renal vascular resistance (RVR), urinary flow (UF) and glomerular filtration rate (GFR). The niquim venom (1 µg/mL), the antivenom alone (1 µg/mL) or the venom incubated with antivenom were added to the system 30 minutes after the beginning of each perfusion. Previous works have...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Thalassophryne nattereri; Antivenom; Kidney.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000100011
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Atorvastatin Has no Effects on Kidney Tissues of Wistar Albino Rats in the Long-Term Intake: An Electron Microscopic Study International Journal of Morphology
Aktas,Ayfer; Serhan Tasdemir,M; Cudi Tuncer,M; Nergiz,Yusuf; Akkus,Murat; Bagriyanik,Hüsnü Alper.
In this study, we evaluated the ultrastructural findings of kidney with systemic administration of different doses of atorvastatin in a rat model. Statins may have anti-inflammatory effects that would play a role in preventing the cellular damage. The aim of this study was to investigate how atorvastatin could play a role in kidney tissues. Forty adult male Wistar albino rats (200­250 g) were randomly divided into 4 groups of ten rats each (A1, A2, A3 and Control). Three different doses of atorvastatin were used to determine the effects on kidney tissues during 90 day period. The kidneys of A1 (0.1-mg group), A2 (0.5-mg group) and A3 (1-mg group) group were excised and the tissues were examined after the 90 days by transmission electron microscopy. Despite...
Tipo: Journal article Palavras-chave: Kidney; Wistar-albino rat; Statins; Atorvastatin; Ultrastructural.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100025
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Bilateral Origin of the Testicular Arteries from the Lower Polar Accessory Renal Arteries International Journal of Morphology
Panagouli,Eleni; Lolis,Evangelos; Venieratos,Dionysios.
The gonadal arteries (testicular or ovarian arteries) emerge normally from the lateral aspect of the abdominal aorta, a little inferior to the renal arteries. Several other sites of origin of these arteries have been recorded with the renal and accessory renal arteries being the most common. In the present case report, the testicular arteries originated from the lower polar accessory renal arteries in both sides. The testicular veins followed had the usual origin and course, while an accessory renal vein was observed only in the right side. These anomalies were combined with an abnormal left ureter exiting from the lower pole of the kidney. Only one male cadaver among 77 adult human cadavers of Caucasian origin presented this set of variations (frequency:...
Tipo: Journal article Palavras-chave: Gonadal arteries; Kidney; Ureter; Abdominal aorta.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000400010
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Can Formaldehyde Exposure Induce Histopathologic and Morphometric Changes on Rat Kidney? International Journal of Morphology
Golalipour,Mohammad Jafar; Azarhoush,Ramin; Ghafari,Soraya; Davarian,Ali; Fazeli,Seyyed Amirhossein.
Formaldehyde is used traditionally for fixing the cadaver, and vaporized during dissection and practical studying on cadaver. This study was designed to determine the histopathologic and morphometric changes of rat kidney while all of the experiments were exposed to formaldehyde for 18 weeks. 28 male albino Wistar rats were divided into the following three experimental groups (E1: 2hrs/d, 2d/w; E2: 2hrs/d, 4d/w; E3: 4hrs/d, 4d/w) and one control group (C). when the exposure period was expired the animals were anaesthetized with chloroform. After cervical dislocation, the abdomen was dissected and the kidneys were taken. The kidney specimens were sectioned and stained with Haematoxylin and Eosin technique for histologic and morphometric study. Data were...
Tipo: Journal article Palavras-chave: Formaldehyde; Exposure; Histology; Kidney; Rat; Morphometry.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400037
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Characterization of renin mRNA expression and enzyme activity in rat and mouse mesangial cells BJMBR
Andrade,A.Q.; Casarini,D.E.; Schor,N.; Boim,M.A..
Renin is an enzyme involved in the stepwise generation of angiotensin II. Juxtaglomerular cells are the main source of plasma renin, but renin activity has been detected in other cell types. In the present study we evaluated the presence of renin mRNA in adult male Wistar rat and mouse (C-57 Black/6) mesangial cells (MC) and their ability to process, store and release both the active and inactive forms of the enzyme. Active renin and total renin content obtained after trypsin treatment were estimated by angiotensinogen consumption analyzed by SDS-PAGE electrophoresis and quantified by angiotensin I generation by HPLC. Renin mRNA, detected by RT-PCR, was present in both rat and mouse MC under basal conditions. Active renin was significantly higher...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Renin; Prorenin; Mesangial cell; Kidney.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000100003
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Cinetica do fosforo em tecidos de caprinos. Repositório Alice
BUENO, M. S.; VITTI, D. M. S. S..
O objetivo do trabalho foi determinar a cinetica do P em algns tecidos de caprinos submetidos a dietas com quantidade de P insuficiente, adequada e elevada. Foram utilizados nove caprinos machos castrados da raca Alpina, alojados em gaiolas individuais e alimentados por 29 dias com dietas compostas de feno e concentrado suplementado com 0,1 ou 2 g de P/dia na forma de fosfato bicalcico. No 22. dia os animais receberam injecao de 7,4 MBq de P na jugular esquerda. No 8. dia apos a aplicacao do tracador, os animais foram abatidos e coleraram-se amostras de figado, rim, coracao e musculo para determinacao da cinetica do P. As variaveis foram submetidas a regressao com o consumo de P. Os teores de P no coracao, musculo e rim mostraram relacao linear positiva e...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Atividade especifica; Plasma; Figado; Rim; Coracao; Musculo; Osso; Specific activity; Liver; Kidney; Heart; Muscle; Bone.
Ano: 1998 URL: http://www.alice.cnptia.embrapa.br/handle/doc/87332
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Dermatan sulfate reduces monocyte chemoattractant protein 1 and TGF-β production, as well as macrophage recruitment and myofibroblast accumulation in mice with unilateral ureteral obstruction BJMBR
Belmiro,C.L.R.; Gonçalves,R.G.; Kozlowski,E.O.; Werneck,A.F.; Takyia,C.M.; Leite-Jr.,M.; Pavão,M.S.G..
Selectins play an essential role in most inflammatory reactions, mediating the initial leukocyte-rolling event on activated endothelium. Heparin and dermatan sulfate (DS) bind and block P- and L-selectin function in vitro. Recently, we reported that subcutaneous administration of DS inhibits colon inflammation in rats by reducing macrophage and T-cell recruitment and macrophage activation. In the present study, we examined the effect of porcine intestinal mucosa DS on renal inflammation and fibrosis in mice after unilateral ureteral obstruction (UUO). Twenty-four adult male Swiss mice weighing 20-25 g were divided into 4 groups: group C (N = 6) was not subjected to any surgical manipulation; group SH (N = 6) was subjected to surgical manipulation but...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Glycosaminoglycans; Dermatan sulfate; Kidney; Inflammation.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000700003
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Detection of cytomegalovirus infections by PCR in renal transplant patients BJMBR
Costa,S.C.B.; Miranda,S.R.P.; Alves,G.; Rossi,C.L.; Figueiredo,L.T.M.; Costa,F.F..
Cytomegalovirus (CMV) is the single most important infectious agent affecting recipients of organ transplants. To evaluate the incidence and the clinical importance of CMV infection in renal transplants in Brazil, 37 patients submitted to renal allograft transplants were tested periodically for the presence of cytomegalovirus DNA in urine using the polymerase chain reaction (PCR), and for the presence of IgM and IgG antibodies against CMV by enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence (IIF). The PCR-amplified products were detected by gel electrophoresis and confirmed by dot-blot hybridization with oligonucleotide probes. Thirty-two of the 37 patients (86.4%) were positive by at least one of the three methods. In six patients,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Transplantation; CMV; PCR; Kidney.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000800004
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Diabetic nephropathy in dogs: literature review MV&Z
Martorelli, Cínthia Ribas; Kogika, Márcia Mery; Caragelasco, Douglas Segalla.
Diabetes mellitus caused by insulin deficiency and chronic hyperglycemia usually presents complications including cataract, retinopathy, recurrent infections and ketoacidosis. Chronic hyperglycemia can cause long-term complications such as diabetic nephropathy. In humans, diabetic nephropathy is characterized mainly by glomerular injury and usually it is associated with systemic hypertension. The mechanisms proposed for the pathogenesis of diabetic nephropathy could be glomerular injury, as well as renal tubular damage. However, there are few studies analyzing the relationship between diabetes mellitus and kidney damage in dogs. The objective of this review is to clarify the pathophysiological mechanisms of diabetic nephropathy and to analyze the available...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Canine; Kidney; Hyperglycemia; Diabetes mellitus canino; Rim; Hiperglicemia; Diabetes mellitus.
Ano: 2018 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/37712
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Echobiometrics kidney and renal artery triplex doppler of canine fetuses Arq. Bras. Med. Vet. Zootec.
Feliciano,M.A.R.; Cardilli,D.J.; Nepomuceno,A.C.; Crivalero,R.M.; Silva,M.A.M.; Coutinho,L.N.; Oliveira,M.E.F.; Vicente,W.R.R..
The aim of this study was to assess the sogographic parameters and biometry of canine fetal kidneys using the B mode, and to determinate the vascular index of the fetal renal arteries using the Doppler Triplex. Twenty four Shi-tzu and Pug, weighting between 4 and 10kg, aging between 4 and 6 years old were evaluated. The B mode, the fetal renal echobiometry and regularity of the renal surface, echotexture and cortex:medular ratio were evaluated during the 5th, 6th, 7th and 8th weeks of pregnancy. At the same time point of the B mode evaluation, the Doppler Triplex was carried out to assess the sistolic peak velocity (SPV), end diastolic velocity (EDV), vascular resistive (RI) and pulsatility index (PI). B mode revealed no fetal renal abnormalities and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Canine; Kidney; Fetuses; B-mode ultrasound; Vascular index.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000200018
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Effect of antibodies to intercellular adhesion molecule type 1 on the protection of distant organs during reperfusion syndrome in rats BJMBR
Souza-Moraes,M.R.; David-Filho,R.; Baptista-Silva,J.C.C.; Ullian,M.; Franco,M.F.; Gabriel Jr.,A.; Smith,B.; Burihan,E..
We investigated kidney and lung alterations caused by intercellular adhesion molecule type 1 (ICAM-1) blockade after ischemia and reperfusion of hind limb skeletal muscles. Rats were submitted to ligature of the infrarenal aorta for 6 h. The animals were randomized into three groups of 6 rats each: group I, sacrificed after ischemia; group II, reperfusion for 24 h, and group III, reperfusion for 24 h after receiving monoclonal anti-ICAM-1 antibodies. At the end of the experiment, blood samples were collected for creatinine, lactate dehydrogenase, creatine phosphokinase, potassium, pH and leukocyte counts. Samples were taken from the muscles of the hind limbs and from the kidneys and lungs for histological analysis and measurement of the neutrophil...
Tipo: Info:eu-repo/semantics/article Palavras-chave: ICAM-1; Neutrophil; Myeloperoxidase; Kidney; Lung; Reperfusion.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000500007
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Effects of Aspartame on Fetal Kidney: A Morphometric and Stereological Study International Journal of Morphology
Martins,Marielza R Ismael; Azoubel,Reinaldo.
The objective of this study was the evaluation of aspartame effects on morphometric alterations of the glomerulus, proximal and distal convoluted tubules and collecting ducts of the rat fetal kidney during organogénesis. Fifteen pregnant rats averaging 24 g body weight, were divided into 3 groups (n=5 each) of controls, rats treated with aspartame exposed to room temperature and rats treated with aspartame heated to 40°C. Animals were given 14mg / kg aspartame by the intragastric route on the 9th, 10th, and 11th days of pregnancy. Karyometric and stereological techniques estimated morphological changes. A significant decrease of fetal body weight was observed in the group given aspartame kept at room temperature, compared to controls. Karyometry permitted...
Tipo: Journal article Palavras-chave: Aspartame; Kidney; Morphometry.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400004
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