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ACT Now or Later: The Economics of Malaria Resistance AgEcon
Laxminarayan, Ramanan.
In the past, malaria control efforts in sub-Saharan Africa have relied on a combination of vector control and effective treatment using chloroquine. With increasing resistance to chloroquine, attention has now turned to alternative treatment strategies to replace this failing drug. Although there are strong theoretical arguments in favor of switching to more expensive artemisinin-based combination treatments (ACTs), the validity of these arguments in the face of financial constraints has not been previously analyzed. In this paper, we use a Bioeconomic model of malaria transmission and evolution of drug resistance to examine questions of optimal treatment strategy and coverage when drug resistance places an additional constraint on choices available to the...
Tipo: Working or Discussion Paper Palavras-chave: Malaria; Mathematical models; Drug resistance; Bioeconomics; Health Economics and Policy; I10; I19; C61.
Ano: 2003 URL: http://purl.umn.edu/10699
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Agricultural efficiency, malaria incidence and health expenses among Ugandan farmers AgEcon
Ulimwengu, John M.; Badiane, Ousmane.
The importance of health in promoting economic development has been forcefully stated by the World Health Organization’s Commission on Macroeconomics and Health. In this paper, we look at the impact of own household health expenses on malaria incidence and ultimately on agricultural efficiency. We use a non-parametric method to estimate agricultural efficiency, therefore avoiding the issue of identification of the proper household agricultural production function. In addition the simar-wilson approach followed in this paper accounts for bias induced by serial correlation among farmers. A Tobit model with endogenous health production function is used to estimate the impact of malaria incidence on agricultural efficiency. Data come from the 2006 National...
Tipo: Conference Paper or Presentation Palavras-chave: Malaria; Efficiency; Tobit; Health; Agriculture; Expenses; Household; Production; Agricultural and Food Policy; Health Economics and Policy; Productivity Analysis.
Ano: 2011 URL: http://purl.umn.edu/103839
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An investigation of the relationship between depth to groundwater and malaria prevalence, Punjab, Pakistan AgEcon
Donnelly, M.J.; Birley, M.H.; Konradsen, Flemming.
Tipo: Working or Discussion Paper Palavras-chave: Groundwater; Malaria; Waterborne diseases; Land use; Public health; Farmers; Institutions; Infrastructure; Maps; Statistics; Rice; Farm Management; Health Economics and Policy.
Ano: 1997 URL: http://purl.umn.edu/113607
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Aspectos atuais da distribuição geográfica de Anopheles (Kerteszia) cruzii Dyar & Knab, 1908 no estado do Espírito Santo, Brasil Entomología
Rezende,Helder Ricas; Cerutti Junior,Crispim; Santos,Claudiney Biral dos.
Anopheles cruzii was registered in Espírito Santo state both in 1957 and 1968. Our study provides additional evidence of its presence, including municipalities that were non mentioned before. Anopheles captures undertaken between 1998 and 2003 pointed out a distribution restricted to the forested outskirts of the mountains in the highland area of the state. Its epidemiological role is suggested by the simultaneous presence of malaria cases in the same municipalities.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Anopheles cruzii; Malaria; Geographical distribution; Espírito Santo; Brazil.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0328-03812005000100011
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Avaliação sazonal da produção de quassina em plantas adultas de quina (Quassia amara L.) nas condições ambientais de Belém, PA. Repositório Alice
TEIXEIRA, S. C. F.; ROCHA NETO, O. G. da..
1998
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Quina; Planta medicinal; Produção de quassina; Crescimento; Antigeno; Malaria; Quassia amara; Drug plants; Growth; Antigens.
Ano: 1998 URL: http://www.alice.cnptia.embrapa.br/handle/doc/395031
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Candidacy of liver stage antigen-1 for Plasmodium falciparum vaccine development OAK
Taylor-Robinson, Andrew W.; Heal, Karen G..
Malaria is the world's most important parasitic disease, imposing a massive health burden on people living in the tropics, often in the poorest countries. The vast majority of deaths in humans from malaria are caused by one species of the hemoprotozoan, Plasmodium falciparum., against which effective control measures are urgently needed. The global situation has deteriorated in recent times due to increased resistance of the anopheline mosquitoes that transmit P. falciparum to insecticides, and of the parasites themselves to drug therapy. An efficacious and cost-effective vaccine against this parasite is considered a public health priority. A vaccine that targets pre-erythrocytic parasites in the liver could potentially prevent clinical disease by blocking...
Palavras-chave: Malaria; Plasmodium falciparum; Liver stage; Vaccine; Cellular immunity.
Ano: 2001 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/133
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Characterization of Plasmodium falciparum glutamate dehydrogenase-soluble antigen BJMBR
Rodríguez-Acosta,A.; Domínguez,N.G.; Aguilar,I.; Girón,M.E..
The major aim of this study was to characterize a soluble Plasmodium falciparum antigen from the plasma of malaria-infected humans and Plasmodium falciparum culture supernatants, using immunoabsorbent techniques and Western blotting. An Mr 60-kDa protein was isolated from the plasma of patients with Plasmodium falciparum malaria by affinity chromatography using rabbit anti-Proteus spp GDH(NADP+) serum as ligand. This protein, present in plasma of patients with acute Plasmodium falciparum infection, in Plasmodium falciparum culture supernatants, and in immune complexes, was tested with Plasmodium falciparum malaria hyperimmune serum from patients living in hyperendemic areas and rabbit anti-Proteus spp GDH(NADP+) serum prepared in the laboratory. In this...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Glutamate-dehydrogenase; Plasmodium falciparum; Exoantigens; Soluble antigens; Malaria; Antigenic enzymes.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000900008
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Criação de uma micoteca de fungos endofíticos de frutas regionais e seu potencial antimalárico. Repositório Alice
SOUZA, K. R. de; ALVES, B. G.; GONÇALVES, K. D.; RAPOSO, D. de S.; SOUSA, T. F.; DANTAS, P. H. S.; FELIX, C. G. S.; KRAMER, Y. V.; SILVA, G. F. da; KOOLEN, H. H. F..
Objetivou-se por meio deste estudo, a criação de uma micoteca de fungos endofíticos associados a frutas regionais e sua avaliação antimalárica.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Fungos endofíticos; Frutas amazônicas; 7º CDMicro; Malaria; Plasmodium.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1095771
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Current policy and status of DDT use for malaria control in Ethiopia, Uganda, Kenya and South Africa. AgEcon
Biscoe, Melanie L.; Mutero, Clifford M.; Kramer, Randall A..
Tipo: Working or Discussion Paper Palavras-chave: Malaria; Waterborne diseases; Disease vectors; Public health; Policy; Ddt; Legal aspects; Pesticide residues; Case studies; Health Economics and Policy; Research and Development/Tech Change/Emerging Technologies; Research Methods/ Statistical Methods; Teaching/Communication/Extension/Profession.
Ano: 2005 URL: http://purl.umn.edu/92015
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Does Reducing Malaria Improve Household Living Standards? AgEcon
Laxminarayan, Ramanan.
Living in malaria-endemic regions places an economic burden on households even if they do not actually suffer an episode of malaria. Households living with endemic malaria are less likely to have access to economic opportunities and may have to modify agricultural practices and other household behavior to adapt to their disease environment. Data from Vietnam demonstrate that reductions in malaria incidence through government-financed malaria control programs can contribute to higher household income for all households living in endemic areas. Empirically, a 10% decrease in malaria cases at the national level translates to a roughly US $30 million annual economic benefit in the form of improved living standards.
Tipo: Working or Discussion Paper Palavras-chave: Malaria; Living standards; Disease; Health Economics and Policy; D1; O1; I0.
Ano: 2003 URL: http://purl.umn.edu/10633
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Epitopic Specificity of the Human Immune Response to the Invariant Region of a Polymorphic Plasmodium faciparum Merozoite Surface Antigen OAK
Rzepczyk, C. M.; Anderson, K. L.; Crurshes, P. A.; Baxter, E. P.; Kere, N.; Irving, D.; Dyer, S.; Jones, G. L..
Merozoite surface antigen 2 (MSA2) is a Plasmodium falciparum vaccine candidate. Antibody responses to MSA2 in Melanesians naturally exposed to P. falciparum were investigated by ELISA using the recombinant MSA2 protein known as Ag 1609 and 65 overlapping synthetic peptides spanning predominantly the conserved N and C terminal regions of MSA2. Significant differences were obtained between control and malaria exposed subjects in the ability of sera to bind to Ag 1609. The median absorbance obtained with control sera was 0.36 whereas that obtained with sera from malaria exposed subjects was 1.8. The sera of ninety-five percent of malaria exposed subjects reacted significantly with Ag 1609. The percentage reactivity of the control sera with Ag 1609 was 39%....
Palavras-chave: Malaria; Merozoite surface antigen 2 (MSA2); Antibody.
Ano: 1992 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/170
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EXPORT AND TRAFFICKING OF Plasmodium PROTEINS WITHIN THE HOST ERYTHROCYTE Acta biol.Colomb.
WISER,MARK F.
The export and trafficking of parasite proteins within the infected erythrocyte is a complex process and not well understood. Export of proteins from the parasite was previously speculated to involve a specialized compartment originally designated as the secondary endoplasmic reticulum of the Apicomplexa, or sERA. The properties of this Plasmodium export compartment are reviewed in regards to more recent observations about the trafficking of Plasmodium proteins within the host erythrocyte. In addition, a calcium ATPase unique to the Apicomplexa and with homology to the sarcoplasmicendoplasmic reticulum calcium ATPase is discussed in the context of this unique export compartment. It is also speculated that the Plasmodium export element, PEXEL, may play a...
Tipo: Journal article Palavras-chave: Secretory pathway; SERCA; Protein trafficking; Malaria.
Ano: 2007 URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-548X2007000200001
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Fishing and poverty levels around Lake Victoria (Kenya) OceanDocs
Abila, R.O.; Omwega, R.N.; Lwenya, C..
Fishing is known to be one of the oldest occupations of mankind and in Lake Victoria (Kenya); it has been largely practiced at artisanal levels. Despite this, poverty amongst the fisher folk remains high. Why the fisher folk remain in perpetual poverty was the key research question for this study. Sampling was conducted on 12 landing beaches between June and August 2004. Data was obtained using survey questionnaires; personal interviews were made using open-ended questions and beach observations. Results from this study indicates that 179 fishers sampled earned an average income of Ksh. 107,063 each in a year with modal income of Ksh. 57,600 while in a day they earned an average income of Ksh. 518 each with modal income of Ksh. 200. Fishers perceived that...
Tipo: Proceedings Paper Palavras-chave: Fishing; Artisanal fishing; Lake fisheries; Socioeconomic aspects; Fishery economics; Public health; Malaria; Fishery management; Pricing.
Ano: 2006 URL: http://hdl.handle.net/1834/1495
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Health impacts of small reservoirs in Burkina Faso. AgEcon
Boelee, Eline; Cecchi, Philippe; Kone, Andre.
In Burkina Faso, at least 1,700 small reservoirs have been constructed, most of them during the last 30 years. Numerous and scattered, these beneficial multipurpose systems combine productive with domestic water uses. However, their environmental and health impacts remain insufficiently documented. This report combines data from different sources into syntheses and national maps, with a focus on water-related diseases. The mitigation of negative impacts requires an integrated approach to specifically identify the enhancing and limiting factors that influence environmental impacts and the transmission of diseases around reservoirs. Public awareness campaigns need to accompany the promotion of preventive and curative measures and the development of...
Tipo: Working or Discussion Paper Palavras-chave: Reservoirs; Health hazards; River basins; Water resources development; Environmental effects; Waterborne diseases; Malaria; Schistosomiasis; Control methods; Water policy; Environmental Economics and Policy; Health Economics and Policy; Land Economics/Use; Resource /Energy Economics and Policy.
Ano: 2009 URL: http://purl.umn.edu/91869
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Hepatic Oxidative Stress and Antioxidant Defenses During Chloroquine-Resistant and Sensitive Plasmodium berghei Infecton in Mice OAK
Srivastava, Pratima; Pandey, Vikaash C..
Palavras-chave: Malaria; Plasmodium berghei; Chloroquine-resistant; Chloroquine-sensitive; Oxidative damage; Superoxide scavenging system.
Ano: 1996 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/245
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Impact of irrigation on poverty and environment in Ethiopia. Draft Proceeding of the Symposium and Exhibition held at Ghion Hotel, Addis Ababa, Ethiopia 27th -29th November, 2007 AgEcon
Awulachew, Seleshi Bekele; Loulseged, Makonnen; Yilma, Aster Denekew.
Tipo: Presentation Palavras-chave: Poverty; Crop management; Irrigated farming; Rainfed farming; Irrigation systems; Food security; Water harvesting; Institutions; Environmental effects; Public health; Malaria; GIS; Remote sensing; Crop Production/Industries; Environmental Economics and Policy; Farm Management; Food Consumption/Nutrition/Food Safety; Food Security and Poverty; Health Economics and Policy; Institutional and Behavioral Economics; Resource /Energy Economics and Policy.
Ano: 2008 URL: http://purl.umn.edu/118410
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In vivo antimalarial activity of semi-synthetic derivates of 4-nerolidylcatechol (4-NC). Repositório Alice
NOGUEIRA, K. L.; SILVA, L. F. R.; PINTO, A. C. S.; TADEI, W. P.; CHAVES, F. C. M.; POHLIT, A. M..
2014
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Malaria; Tropical disease; Piper peltata; Caapeba.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/998068
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Independent Associations of Maternal Education and Household Wealth with Malaria Risk in Children Ecology and Society
Despite evidence that they play similar but independent roles, maternal education and household wealth are usually conflated in studies of the effects of socioeconomic status (SES) on malaria risk. Demographic and Health Survey and Malaria Indicator Survey data from nine countries in sub-Saharan Africa were used to explore the relationship of malaria parasitemia in children with SES factors at individual and cluster scales, controlling for urban/rural residence and other important covariates. In multilevel logistic regression modeling, completion of six years of maternal schooling was associated with significantly lower odds of infection in children (OR = 0.73), as was a household wealth index at the 40th percentile compared to the lowest percentile (OR =...
Tipo: Peer-Reviewed Reports Palavras-chave: Demographic and Health Survey; DHS; Malaria; Malaria Indicator Survey; Maternal education; MIS; Multilevel modeling; Socioeconomic factors.
Ano: 2014
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Learning, Misallocation, and Technology Adoption: Evidence from New Malaria Therapy in Tanzania AgEcon
Adhvaryu, Achyuta.
I show that malaria misdiagnosis, common in resource-poor settings, decreases the expected effectiveness of an important new therapy–since only a fraction of treated individuals have malaria–and reduces the rate of learning via increased noise. Using pilot program data from Tanzania, I exploit variation in the location and timing of survey enumeration to construct reference groups composed of randomly chosen, geographically and temporally proximate acutely ill individuals. I show that learning is stronger and adoption rates are higher in villages with more misdiagnosis. Subsidizing diagnostic tools or improving initial targeting of new technologies may thus accelerate uptake through learning.
Tipo: Working or Discussion Paper Palavras-chave: Technology adoption; Learning; Malaria; Tanzania; Health Economics and Policy; International Development; Research and Development/Tech Change/Emerging Technologies; I15; O12; O33.
Ano: 2011 URL: http://purl.umn.edu/115712
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Malaria and National Income: Examining a Two Way Causal Relationship AgEcon
Datta, Saurabh; Reimer, Jeffrey J..
Simple plots of data show that malaria has a negative correlation with national income per capita, whether looking across countries at a point in time, or looking at a single country over time. Some countries have been able to move from an equilibrium characterized by low income and high malaria, to a new equilibrium with higher income and lower rates of malaria. This study develops and estimates a simultaneous equations model to explain these changes. We distinguish three potential causal chains: (a) the ability for decreases in malaria to increase income, (b) the ability for increases in income to reduce malaria (reverse causality), and (c) external factors that may lead to both higher income and lower malaria (incidental association). We find that...
Tipo: Conference Paper or Presentation Palavras-chave: Antipoverty; GDP; Health; Economic growth; Malaria; Simultaneous equations; Health Economics and Policy; International Development; Labor and Human Capital; I1; I3; O1; O2.
Ano: 2010 URL: http://purl.umn.edu/61179
Registros recuperados: 32
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