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Registros recuperados: 35
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A naturally occurring mutation K220T in the pleiotropic activator PrfA of Listeria monocytogenes results in a loss of virulence due to decreasing DNA-binding affinity Inra
Velge, P.; Herler, M.; Johansson, J.; Roche, S.; Témoin, S.; Fedorov, A. A.; Gracieux, P.; Almo, S. C.; Goebel, W.; Cossart, P..
The sequencing of prfA, encoding the transcriptional regulator of virulence genes, in 26 low virulence field Listeria monocytogenes strains showed that eight strains exhibited the same single amino-acid substitution: PrfAK220T. These strains exhibited no expression of PrfA-regulated proteins and thus no virulence. This substitution inactivated PrfA, since expression of the PrfAK220T mutant gene in an EGDΔprfA strain did not restore the haemolytic and phosphatidylcholine phospholipase C activities, in contrast to the wild-type prfA gene. The substitution of the lysine at position 220 occurred in the helix αH. However, the data showed that the PrfAK220T protein is dimerized just as well as its wild-type counterpart, but does not bind to PrfA boxes....
Tipo: Journal Article Palavras-chave: LISTERIA MONOCYTOGENES; PROTEINE; FACTEUR DE VIRULENCE; BACTERIE PATHOGENE; ADN; SEQUENCE NUCLEOTIDIQUE; REGULATION; TRANSCRIPTION; VIRULENCE; EXPRESSION DES GENES; ACIDE AMINE; MUTATION; RT-PCR; ELECTROPHORESE; ENZYME; ARN POLYMERASE.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009c1895b3c&uri=/notices/prodinra1/2009/11/
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Abundance of IFN-alpha and IFN-gamma mRNA in blood of resistant and susceptible chickens infected with Marek's disease virus (MDV) or vaccinated with turkey herpesvirus; and MDV inhibition of subsequent induction of IFN gene transcription Inra
Quéré, P.; Rivas, C.; Ester, K.; Novak, R.; Ragland, W.L..
The effects of the very virulent RB-1B strain of Marek's disease virus (MDV) and turkey herpesvirus (HVT), a vaccinal strain, on abundance of IFN mRNA in the blood were investigated. MDV and HVT infection did not change the circulating level of IFN-γ mRNA 1 and 7 days p.i., but they increased IFN-αmRNA levels slightly in genetically susceptible (to tumour development) B13/B13 chickens. The total number of circulating leukocytes was unchanged and increase in message was accompanied by an increase in circulating CD8α+ and MHC Class II+ cells. On the contrary, both viruses slightly increased IFN-γ transcripts and decreased IFN-α transcripts in genetically resistant B21/B21 chickens. Further, oncogenic MDV was able to block the response to inactivated...
Tipo: Journal Article Palavras-chave: IFN; MALADIE DE MAREK; TRANSCRIPTION; IMMUNODEPRESSION; VACCINATION; HERPESVIRIDAE; HERPES VIRUS.
Ano: 2005 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB0500018087108640&uri=/notices/prodinra1/2010/10/
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Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity IRD
Henegar, C.; Tordjman, J.; Achard, V.; Lacasa, D.; Cremer, I.; Guerre-Millo, M.; Poitou, C.; Basdevant, A.; Stich, V.; Viguerie, N.; Langin, D.; Bedossa, P.; Zucker, Jean-Daniel; Clement, K..
Tipo: Text Palavras-chave: MALADIE NUTRITIONNELLE; OBESITE; BIOLOGIE MOLECULAIRE; METABOLISME; PHENOTYPE; ARN; CYTOLOGIE; EXPRESSION DES GENES; MICROESSAI; TECHNIQUE PCR; FIBROSE; TRANSCRIPTION; TISSU ADIPEUX.
Ano: 2008 URL: http://www.documentation.ird.fr/hor/fdi:010049779
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Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels Inra
Bruhat, A.; Jousse, C.; Wang, X.Z.; Ron, D.; Ferrara, M.; Fafournoux, P..
Tipo: Journal Article Palavras-chave: GENE CHOP; EXPRESSION DES GENES; TRANSCRIPTION; LEUCINE.
Ano: 1997 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB0000031721079774&uri=/notices/prodinra1/2010/09/
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Anaerobic sugar catabolism in Lactococcus lactis: genetic regulation and enzyme control over pathway flux Inra
Cocaign-Bousquet, M.; Even, S.; Lindley, N.D.; Loubière, P..
Lactic acid bacteria and particularly Lactococcus lactis are widely used for the production of lactic acid in fermented foods. Control of the catabolic rate in L. lactis, i.e., the rate of lactic acid production, appears to be determinant for dairy product quality. While the mechanisms involved in control have not been totally elucidated, they seem to depend upon the strain and the growth conditions. Furthermore, it remains unclear whether the catabolic rate is controlled at the level of transcription, translation or enzyme activity. The recent sequencing of the L. lactis genome has brought novel insights to physiologic studies of the bacteria. This review discusses both genetic information and metabolic studies concerning anaerobic sugar...
Tipo: Journal Article Palavras-chave: ANAEROBIE; REGULATION GENETIQUE; CATABOLISME; CROISSANCE BACTERIENNE; FACTEUR DU MILIEU; SEQUENCE NUCLEOTIDIQUE; PYRUVATE; EXPRESSION DES GENES; TRANSCRIPTION.
Ano: 2002 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB0400023343102184&uri=/notices/prodinra1/2010/09/
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Analyse structurale et transcriptionnelle des rétrotransposons du génome de la vigne, Vitis vinifera L. Inra
Moisy, C..
Les variétés de vigne (Vitis vinifera L.) sont composées d’un ensemble de clones, tous issus de la même et unique plante propagée par multiplication végétative sur de longues périodes. Ce processus doit en principe assurer la transmission du patrimoine génétique de la plante mère à la plante fille, cependant des mutations spontanées peuvent apparaître et être, dans certains cas, à l’origine de nouveaux génotypes. Les éléments transposables, par la variabilité génétique que peut générer leur mobilité, sont une source potentielle de mutation. Dans un contexte général de compréhension des mécanismes biologiques qui participent à l’évolution des génomes au cours des cycles de multiplication végétative, l’objectif de la thèse est d’étudier la structure et la...
Tipo: Thesis Palavras-chave: TVV1; VINE-1; GRET1; DIVERSITE INTRA-VARIETALE; RETROTRANSPOSON; ELEMENTS MOBILES; STRESS; TRANSCRIPTION; RT-PCR.
Ano: 2008 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009f41483eb&uri=/notices/prodinra1/2009/02/
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Analysis of CATMA transcriptome data identifies hundreds of novel functional genes and improves gene models in the Arabidopsis genome Inra
Aubourg, S.; Martin-Magniette, M.L.; Brunaud, V.; Taconnat, L.; Bitton, F.; Balzergue, S.; Jullien, P.E.; Ingouff, M.; Thareau, V.; Schiex, T.; Lecharny, A.; Renou, J.P..
Background: Since the finishing of the sequencing of the Arabidopsis thaliana genome, the Arabidopsis community and the annotator centers have been working on the improvement of gene annotation at the structural and functional levels. In this context, we have used the large CATMA resource on the Arabidopsis transcriptome to search for genes missed by different annotation processes. Probes on the CATMA microarrays are specific gene sequence tags (GSTs) based on the CDS models predicted by the Eugene software. Among the 24 576 CATMA v2 GSTs, 677 are in regions considered as intergenic by the TAIR annotation. We analyzed the cognate transcriptome data in the CATMA resource and carried out data-mining to characterize novel genes and improve gene models....
Tipo: Journal Article Palavras-chave: ADNC; EXPRESSION DES GENES; SEQUENCE NUCLEOTIDIQUE; ARABIDOPSIS THALIANA; GENOME; MODELE; METHODE STATISTIQUE; PROTEINE; TRANSCRIPTION; ARN MESSAGER; PCR; RT-PCR CDNA MICROARRAY DATA; EXPRESSION PROFILES; SEQUENCE TAGS; ANNOTATION; THALIANA; NORMALIZATION; REGIONS; TOOLS.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD20116115e9a4&uri=/notices/prodinra1/2011/03/
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Cap-poly(A) synergy in mammalian cell-free extracts. Investigation of the requirements for poly(A)-mediated stimulation of translation initiation Inra
Michel, Y.M.; Poncet, D.; Piron, M.; Kean, K.M.; Borman, A.M..
Tipo: Journal Article Palavras-chave: IMMUNOLOGIE MOLECULAIRE; STIMULATION; POLYADENYLATION; TRANSCRIPTION; INFECTION VIRALE; ADENINE; STRUCTURE.
Ano: 2000 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB0300012841095688&uri=/notices/prodinra1/2010/09/
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Characterization of a novel thyroid hormone receptor alpha variant involved in the regulation of myoblast differentiation Inra
Casas, F.; Busson, M.; Grandemange, S.; Seyer, P.; Carazo, A.; Pessemesse, L.; Wrutniak-Cabello, C.; Cabello, G..
The regulation of gene expression by thyroid hormone (T-3) involves binding of the hormone to nuclear receptors [ thyroid hormone receptor (TR)] acting as T-3-dependent transcription factors encoded by TR alpha (NR1A1) and TR beta (NR1A2) genes. Several TR alpha variants have already been characterized, but only some of them display T-3 binding activity. In this study, we have identified another transcript, TR alpha-Delta E6, produced by alternative splicing with microexon 6b instead of exon 6. This splicing leads to the synthesis of a protein devoid of a hinge domain. The TR alpha-Delta E6 transcript is detected in all mouse tissues tested. Although TR alpha-Delta E6 did not bind DNA, its expression induced a TR alpha 1 sequestration in the cytoplasm....
Tipo: Journal Article Palavras-chave: TR ALPHA; MYOBLAST; TRANSCRIPTION; TRIIODOTHYRONINE.
Ano: 2006 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2007fe0b10ad&uri=/notices/prodinra1/2007/09/
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Cloning of a cDNA encoded by a member of the Arabidopsis thaliana ATP sulfurylase multigene family. Expression studies in yeast and in relation to plant sulfur nutrition Inra
Logan, H.M.; Cathala, N.; Grignon, C.; Davidian, J.C..
Tipo: Journal Article Palavras-chave: ARABIDOPSIS THALIANA; ATP; SULFURYLASE; CLONAGE MOLECULAIRE; ADNC; SEQUENCE NUCLEOTIDIQUE; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGUE; ACTIVITE ENZYMATIQUE; TRANSCRIPTION; SULFATE; BRASSICA NAPUS.
Ano: 1996 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB0200029830090142&uri=/notices/prodinra1/2010/09/
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Crencas e lendas do Uaupes IRD
Brüzzi Alves da Silva, P.A.; Buchillet, Dominique (collab.).
Tipo: Text Palavras-chave: SOCIETE TRADITIONNELLE; COMMUNAUTE AMERINDIENNE; CULTURE POPULAIRE; CONTE; LITTERATURE ORALE; CROYANCE; MYTHE D'ORIGINE; COSMOGONIE; SYSTEME DE REPRESENTATIONS; ANTHROPOLOGIE CULTURELLE; TRANSCRIPTION; ANTHOLOGIE.
Ano: 1994 URL: http://www.documentation.ird.fr/hor/fdi:010020940
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Effect of Retinoids on UDP-Glucuronosyltransferase 2B7 mRNA Expression in Caco-2 Cells Inra
Lu, Y.; Bratton, S.; Heydel, J.M.; Radominska-Panndya, A..
Human UDP-glucuronosyltransferase 2B7 (UGT2B7) is one of the major isoforms involved in the glucuronidation of endogenous compounds and xenobiotics. This isoform is the only human UGT shown to glucuronidate retinoids and their oxidized derivatives. In this study, the effects of all-trans retinoic acid (atRA), 9-cis RA, and the RAR agonist TTNPB, on UGT2B7 and UGT2B15 mRNA expression in Caco-2 cells have been examined. Each of these retinoids significantly suppressed UGT2B7 mRNA expression in a concentration-dependent manner with IC50 values of 3.5, 0.3, and 0.2 mM, respectively. However, no inhibition was observed when two other UGTs, UGT2B15 or -1A6, were exposed to atRA, 9-cis RA, or TTNPB, demonstrating that the inhibitory effect of retinoids...
Tipo: Journal Article Palavras-chave: HUMAN CYTOCHROME-P450 ISOFORMS; RESPONSE ELEMENT; VITAMIN-A; X-RECEPTOR; ACTIVE METABOLITE; BETA-GLUCURONIDE; DOWN-REGULATION; ACID; TRANSCRIPTION; GENE UDP-GLUCURONOSYLTRANSFERASE(UGT); RETINOID; SUPPRESSION; CACO-2 CELLS.
Ano: 2008 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2010354c66ec&uri=/notices/prodinra1/2011/02/
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Fast, reversible interaction of prion protein with RNA aptamers containing specific sequence patterns Inra
Mercey, R.; Lantier, I.; Maurel, M.C.; Grosclaude, J.; Lantier, F.; Marc, D..
One of the unsolved problems in prion diseases relates to the physiological function of cellular prion protein (PrP), of which a misfolded isoform is the major component of the transmissible spongiform encephalopathies agent. Knowledge of the PrP-binding molecules may help in elucidating its role and understanding the pathological events underlying prion diseases. Because nucleic acids are known to bind PrP, we attempted to identify the preferred RNA sequences that bind to the ovine recombinant PrP. An in vitro selection approach (SELEX) was applied to a pool of 80-nucleotide(nt)-long RNAs containing a randomised 40-nt central region. The most frequently isolated aptamer, RM312, was also the best ligand (20 nM KD value), according to both surface plasmon...
Tipo: Journal Article Palavras-chave: SEQUENCE; AMPLIFICATION; TRANSCRIPTION.
Ano: 2006 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2007b7bf6e45&uri=/notices/prodinra1/2010/10/
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Fungi have three tetraspanin families with distinct functions Inra
Lambou, K; Tharreau, D.; Kohler, A.; Sirven, C; Marguerettaz, M; Barbisan, C; Sexton, A; Kellner, E; Martin, F.; Howlett, B; Orbach, M; Lebrun, MH.
Background: Tetraspanins are small membrane proteins that belong to a superfamily encompassing 33 members in human andmouse. These proteins act as organizers of membrane-signalling complexes. So far only two tetraspanin families have beenidentified in fungi. These are Pls1, which is required for pathogenicity of the plant pathogenic ascomycetes, Magnaporthe grisea,Botrytis cinerea and Colletotrichum lindemuthianum, and Tsp2, whose function is unknown. In this report, we describe a third familyof tetraspanins (Tsp3) and a new family of tetraspanin-like proteins (Tpl1) in fungi. We also describe expression of some of thesegenes in M. grisea and a basidiomycete, Laccaria bicolor, and also their functional analysis in M. grisea. Results: The exhaustive search...
Tipo: Journal Article Palavras-chave: BASIDIOMYCETES; ASCOMYCETES; COPRINUS CINEREUS; LACCARIA BICOLOR; MAGNAPORTHE GRISEA; PROTEINE MEMBRANAIRE; TETRASPANINE; PATHOGENIE; POUVOIR PATHOGENE; INFECTION RICE; BARLEY; GENE EXPRESSION; MYCELIUM; PATHOGENICITY; PLANT PATHOGENIC FUNGI; SURFACE PROTEINS; TRANSCRIPTION; DNA TRANSCRIPTION; MEMBRANE PROTEINS.
Ano: 2008 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD20101f8edf6&uri=/notices/prodinra1/2010/11/
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Genome-wide transcriptome profiling of the early cadmium response of Arabidopsis roots and shoots Inra
Herbette, S.; Taconnat, L.; Hugouvieux, V.; Piette, L.; Magniette, M.L.; Cuine, S.; Auroy, P.; Richaud, P.; Forestier, C.; Bourguignon, J.; Renou, J.P.; Vavasseur, A.; Leonhardt, N..
Transcriptional regulation in response to cadmium treatment was investigated in both roots and leaves of Arabidopsis, using the whole genome CATMA microarray containing at least 24,576 independent probe sets. Arabidopsis plants were hydroponically treated with low (5 mu M) or high (50 mu M) cadmium concentrations during 2, 6, and 30 hours. At each time point, Cd level was determined using ICP-AES showing that both plant tissues are able to accumulate the heavy metal. RT-PCR of eight randomly selected genes confirmed the reliability of our microarray results. Analyses of response profiles demonstrate the existence of a regulatory network that differentially modulates gene expression in a tissue- and kinetic-specific manner in response to cadmium. One of the...
Tipo: Journal Article Palavras-chave: TRANSCRIPTION; METABOLISME SOUFRE MICROARRAY; SULFUR METABOLISM.
Ano: 2006 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2007c9bee07b&uri=/notices/prodinra1/2008/08/
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Histone modifications induced by a family of bacterial toxins Inra
Hamon, M. A.; Batsché, E.; Régnault, B.; Tham, T. N.; Seveau, S.; Muchardt, C.; Cossart, P..
Upon infection, pathogens reprogram host gene expression. In eukaryotic cells, genetic reprogramming is induced by the concerted activation/repression of transcription factors and various histone modifications that control DNA accessibility in chromatin. We report here that the bacterial pathogen Listeria monocytogenes induces a dramatic dephosphorylation of histone H3 as well as a deacetylation of histone H4 during early phases of infection. This effect is mediated by the major listerial toxin listeriolysin O in a pore-forming-independent manner. Strikingly, a similar effect also is observed with other toxins of the same family, such as Clostridium perfringens perfringolysin and Streptococcus pneumoniae pneumolysin. The decreased levels of...
Tipo: Journal Article Palavras-chave: HISTONE; BACTERIE PATHOGENE; AGENT PATHOGENE; EXPRESSION DES GENES; ADN; SEQUENCE NUCLEOTIDIQUE; INFECTION; TRANSCRIPTION; REGULATION; EUCARYOTE; PHOSPHORE; DEPHOSPHORYLATION EPIGENETIC; LISTERIA MONOCYTOGENES; PATHOGENESIS .
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009b0bc6f33&uri=/notices/prodinra1/2009/11/
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Hydrothermal vent shrimps display low expression of the heat-inducible hsp70 gene in nature Inra
Ravaux, J.; Cottin, D.; Chertemps, T.; Hamel, G.; Shillito, B..
The shrimp Rimicaris exoculata swarms over high-temperature chimneys at Mid-Atlantic Ridge hydrothermal sites, thriving in a mixture of hot vent fluid (350°C) and cold seawater (2°C). It may, therefore, be subjected to a thermal regime that is assumed to be stressful for animals. Evaluating the stress status of species in their natural environment is a key issue for understanding the thermal biology of metazoans. In the case of deep-sea species, attempts to quantify natural levels of stress proteins are obviously impaired by deleterious decompression effects during sampling. Here we quantified the heat shock protein (hsp70) mRNA expression of shrimps sampled at a depth of 2300 m and recovered at their native pressure. These shrimps were not...
Tipo: Journal Article Palavras-chave: ARTHROPODA; CRUSTACEA; MALACOSTRACA; ALVINOCARIDIDAE; PROTEINE; STRESS THERMIQUE; EFFET DE LA TEMPERATURE; EFFET DU FROID; ARN MESSAGER; TRANSCRIPTION; EXPRESSION DES GENES; PCR HYDROTHERMAL VENTS; RIMICARIS EXOCULATA; THERMAL BIOLOGY; THERMAL STRESS; HSP70; HEAT SHOCK PROTEIN.
Ano: 2009 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD20101482b1b3&uri=/notices/prodinra1/2010/11/
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Identification of differentially expressed genes in the hydrothermal vent shrimp Rimicaris exoculata exposed to heat stress Inra
Cottin, D.; Shillito, B.; Chertemps, T.; Tanguy, A.; Léger, N.; Ravaux, J..
The deep-sea vent shrimp Rimicaris exoculata dominates the vagile megafauna at most vent sites along the Mid-Atlantic Ridge. This shrimp swarms around the hot end of the hydrothermal biotope where temperature can exceed its critical maximal temperature (33–38.5 ± 2 °C). It may therefore be subjected to a thermal regime that is assumed to be stressful for animals. In this study, we used a global transcriptomic approach by constructing suppression subtractive hybridization cDNA libraries in order to identify specific up- and down-regulated genes in R. exoculata exposed to a severe heat stress (1 h at 30 °C). A total of 218 sequences representing potentially highly expressed genes in thermally stressed shrimp were obtained. Expression of 11 genes involved in...
Tipo: Journal Article Palavras-chave: ARTHROPODA; CRUSTACEA; MALACOSTRACA; ALVINOCARIDIDAE; EXPRESSION DES GENES; STRESS THERMIQUE; EFFET DE LA TEMPERATURE; CLONAGE MOLECULAIRE; ADNC; HYBRIDATION; REGULATION; TRANSCRIPTION; PROTEINE RIMICARIS EXOCULATA; HYDROTHERMAL VENT; HEAT STRESS; SUPPRESSION SUBTRACTIVE HYBRIDIZATION; REAL-TIME PCR.
Ano: 2010 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2010af1480fe&uri=/notices/prodinra1/2010/11/
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Identification of new noncoding RNAs in Listeria monocytogenes and prediction of mRNA targets Inra
Mandin, P.; Repoila, F.; Vergassola, M.; Geissmann, T.; Cossart, P..
To identify noncoding RNAs (ncRNAs) in the pathogenic bacterium Listeria monocytogenes, we analyzed the intergenic regions (IGRs) of strain EGD-e by in silico-based approaches. Among the twelve ncRNAs found, nine are novel and specific to the Listeria genus, and two of these ncRNAs are expressed in a growth-dependent manner. Three of the ncRNAs are transcribed in opposite direction to overlapping open reading frames (ORFs), suggesting that they act as antisense on the corresponding mRNAs. The other ncRNA genes appear as single transcription units. One of them displays five repeats of 29 nucleotides. Five of these new ncRNAs are absent from the non-pathogenic species L. innocua, raising the possibility that they might be involved in...
Tipo: Journal Article Palavras-chave: BACTERIE PATHOGENE; PROTEINE BACTERIENNE; LISTERIA MONOCYTOGENES; VIRULENCE; ARN; ARN MESSAGER; TRANSCRIPTION; TECHNIQUE ANALYTIQUE; SEQUENCE NUCLEOTIDIQUE; GENE ANTISENS; VIRULENCE.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009f388695&uri=/notices/prodinra1/2009/11/
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Inhibition of in vitro reconstitution of rotavirus transcriptionally active particles by anti-VP6 monoclonal antibodies Inra
Kohli, E.; Pothier, P.; Tosser, G.; Cohen, J.; Sandino, A.M.; Spencer, E..
Six monoclonal antibodies specific for the major capsid protein of rotavirus, VP6, previously characterized, were tested in a biological assay for their capacity to block the transcriptase activity associated with the single-shelled particles. The results showed that two MAbs (RV-50 and RV-133), specific for distinct antigenic sites, were able to block the transcription when they were incubated with a purified baculovirus-expressed group A VP6, prior to the reconstitution of the single-shelled particles from the cores, suggesting that at least two domains are involved in active single-shelled particle reconstitution. The results obtained previously from immunochemistry of synthetic peptides did not allow us to attribute this biological activity to a...
Tipo: Journal Article Palavras-chave: ANTICORPS MONOCLONAL; TRANSCRIPTION.
Ano: 1994 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB9500004507051834&uri=/notices/prodinra1/2010/11/
Registros recuperados: 35
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